DNA double-strand break repair and induction of apoptosis in ex vivo irradiated blood lymphocytes in relation to late normal tissue reactions following breast radiotherapy

Breast Radiotherapy ◽

Blood Lymphocytes ◽

Dna Double Strand Break ◽

Induction Of Apoptosis ◽

Tissue Reactions ◽

Normal Tissue Reactions

DNA Double-strand Break Repair and Induction of Apoptosis in Relation to Late Normal Tissue Responses Following Radiation Therapy for Early Breast Cancer

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2012.07.177 ◽

2012 ◽

Vol 84 (3) ◽

pp. S106

Author(s):

M. Chua ◽

S. Davies ◽

L. Gothard ◽

J. Yarnold ◽

K. Rothkamm

Keyword(s):

Breast Cancer ◽

Radiation Therapy ◽

Early Breast Cancer ◽

Normal Tissue ◽

Strand Break ◽

Double Strand Break ◽

Dna Double Strand Break ◽

Tissue Responses ◽

Induction Of Apoptosis

HDAC inhibition radiosensitizes human normal tissue cells and reduces DNA double-strand break repair capacity

Oncology Reports ◽

10.3892/or_00000632 ◽

2009 ◽

Vol 23 (1) ◽

Author(s):

Mahlknecht

Keyword(s):

Normal Tissue ◽

Strand Break ◽

Double Strand Break ◽

Hdac Inhibition ◽

Repair Capacity ◽

Dna Double Strand Break ◽

Tissue Cells ◽

Break Repair ◽

Human Normal Tissue

Ex-vivo slice cultures of tumor tissues confirm the DNA double-strand break repair defect of HPV-positive OPSCC and suggest a defect in the ATM-mediated DNA damage response

10.1055/s-0040-1710927 ◽

2020 ◽

Author(s):

Henrike Barbara Zech ◽

CS Betz ◽

M Kriegs ◽

S Köcher ◽

W Mansour ◽

...

Keyword(s):

Dna Damage ◽

Dna Damage Response ◽

Ex Vivo ◽

Strand Break ◽

Double Strand Break ◽

Dna Double Strand Break ◽

Tumor Tissues ◽

Damage Response ◽

Repair Defect

DNA Double-Strand Break Repair of Blood Lymphocytes and Normal Tissues Analysed in a Preclinical Mouse Model: Implications for Radiosensitivity Testing

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-07-5147 ◽

2008 ◽

Vol 14 (20) ◽

pp. 6546-6555 ◽

Cited By ~ 112

Author(s):

Claudia E. Rübe ◽

Saskia Grudzenski ◽

Martin Kühne ◽

Xiaorong Dong ◽

Nicole Rief ◽

...

Keyword(s):

Mouse Model ◽

Strand Break ◽

Double Strand Break ◽

Blood Lymphocytes ◽

Normal Tissues ◽

Dna Double Strand Break ◽

Residual DNA and chromosomal damage in ex vivo irradiated blood lymphocytes correlated with late normal tissue response to breast radiotherapy

Radiotherapy and Oncology ◽

10.1016/j.radonc.2011.05.071 ◽

2011 ◽

Vol 99 (3) ◽

pp. 362-366 ◽

Cited By ~ 44

Author(s):

Melvin Lee Kiang Chua ◽

Navita Somaiah ◽

Roger A’Hern ◽

Sue Davies ◽

Lone Gothard ◽

...

Keyword(s):

Normal Tissue ◽

Ex Vivo ◽

Tissue Response ◽

Chromosomal Damage ◽

Breast Radiotherapy ◽

Blood Lymphocytes ◽

Normal Tissue Response

Faculty Opinions recommendation of Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1017512.204275 ◽

2004 ◽

Author(s):

Michael B Yaffe

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Dna Double Strand Break ◽

Faculty Opinions recommendation of The Mre11:Rad50 structure shows an ATP-dependent molecular clamp in DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.10202956.12871066 ◽

2011 ◽

Author(s):

Claire Wyman

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Dna Double Strand Break ◽

Faculty Opinions recommendation of The Mre11:Rad50 structure shows an ATP-dependent molecular clamp in DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.10202956.11019054 ◽

2011 ◽

Author(s):

Hao Wu ◽

Jixi Li

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Dna Double Strand Break ◽

Faculty Opinions recommendation of Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1089242.542442 ◽

2007 ◽

Author(s):

Stephen Jackson

Keyword(s):

Chromatin Structure ◽

Strand Break ◽

Double Strand Break ◽

Dna Double Strand Break ◽

Structure Modulation ◽

Faculty Opinions recommendation of Bcl2 negatively regulates DNA double-strand-break repair through a nonhomologous end-joining pathway.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1104438.560671 ◽

2008 ◽

Author(s):

Carlos Telleria

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Nonhomologous End Joining ◽

End Joining ◽

Dna Double Strand Break ◽