scholarly journals Amyloid PETs are commonly negative in suspected Alzheimer’s disease with an increase in CSF phosphorylated-tau protein concentration but an Aβ42 concentration in the very high range: a prospective study

2019 ◽  
Vol 266 (7) ◽  
pp. 1685-1692 ◽  
Author(s):  
Chloé Manca ◽  
Thérèse Rivasseau Jonveaux ◽  
Véronique Roch ◽  
Pierre-Yves Marie ◽  
Gilles Karcher ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Prospective Study ◽  
Tau Protein ◽  
Protein Concentration ◽  
Phosphorylated Tau ◽  
A Prospective Study ◽  
Very High ◽  
Phosphorylated Tau Protein ◽  
High Range

Assay of Plasma Phosphorylated Tau Protein (Threonine 181) and Total Tau Protein in Early-Stage Alzheimer’s Disease

2018 ◽  
Vol 61 (4) ◽  
pp. 1323-1332 ◽  
Author(s):  
Che-Chuan Yang ◽  
Ming-Jang Chiu ◽  
Ta-Fu Chen ◽  
Hui-Ling Chang ◽  
Bing-Hsien Liu ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Tau Protein ◽  
Early Stage ◽  
Phosphorylated Tau ◽  
Total Tau ◽  
Phosphorylated Tau Protein

Phosphorylated tau protein in cerebrospinal fluid is elevated in Alzheimer's disease and other tauopathies

2000 ◽  
Vol 21 ◽  
pp. 155
Author(s):  
Katsuya Urakami ◽  
Hiroyuki Arai ◽  
Koichi Ishiguro ◽  
Hideto Ohno ◽  
Hideki Kohno ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cerebrospinal Fluid ◽  
Tau Protein ◽  
Phosphorylated Tau ◽  
Phosphorylated Tau Protein

CSF Phosphorylated Tau Protein and Mild Cognitive Impairment: A Prospective Study

2000 ◽  
Vol 166 (1) ◽  
pp. 201-203 ◽  
Author(s):  
Hiroyuki Arai ◽  
Koichi Ishiguro ◽  
Hideto Ohno ◽  
Michiko Moriyama ◽  
Nobuo Itoh ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Prospective Study ◽  
Tau Protein ◽  
Phosphorylated Tau ◽  
A Prospective Study ◽  
Phosphorylated Tau Protein

scholarly journals Association of cellular and subcellular calcification with phosphorylated tau in the brains of Alzheimer’s disease patients

2020 ◽  
Author(s):  
Elena Tsolaki ◽  
Lajos Csincsik ◽  
Jing Xue ◽  
Imre Lengyel ◽  
Sergio Bertazzo
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Tau Protein ◽  
Detection Method ◽  
Phosphorylated Tau ◽  
Cell Nuclei ◽  
Middle Temporal ◽  
Early Marker ◽  
Phosphorylated Tau Protein

ABSTRACTDeposition of tau-tangles is an early marker for the development of Alzheimer’s disease (AD). Here we show that these aggregates of phosphorylated tau protein are associated with the calcification of cell nuclei and cell projections, especially in the middle temporal, superior temporal and parahippocampal gyri. This calcification is related to the aetiology of the disease, shedding new light on the mechanisms involved in AD and potentially providing a new detection method for AD progression.

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