Reduced resting-state functional connectivity of the basolateral amygdala to the medial prefrontal cortex in preweaning rats exposed to chronic early-life stress

2018 ◽  
Vol 223 (8) ◽  
pp. 3711-3729 ◽  
Author(s):  
Angela Guadagno ◽  
Min Su Kang ◽  
Gabriel A. Devenyi ◽  
Axel P. Mathieu ◽  
Pedro Rosa-Neto ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Functional Connectivity ◽  
Medial Prefrontal Cortex ◽  
Resting State ◽  
Life Stress ◽  
Early Life ◽  
Basolateral Amygdala ◽  
Early Life Stress ◽  
Resting State Functional Connectivity

scholarly journals Mild early‐life stress exaggerates the impact of acute stress on corticolimbic resting‐state functional connectivity

2021 ◽  
Author(s):  
Huan Wang ◽  
Judith M. C. Leeuwen ◽  
Lycia D. Voogd ◽  
Robbert‐Jan Verkes ◽  
Benno Roozendaal ◽  
...  
Keyword(s):  
Functional Connectivity ◽  
Resting State ◽  
Life Stress ◽  
Early Life ◽  
Acute Stress ◽  
Early Life Stress ◽  
Resting State Functional Connectivity ◽  
The Impact

scholarly journals Regional homogeneity and resting state functional connectivity: Associations with exposure to early life stress

2013 ◽  
Vol 214 (3) ◽  
pp. 247-253 ◽  
Author(s):  
Noah S. Philip ◽  
Yuliya I. Kuras ◽  
Thomas R. Valentine ◽  
Lawrence H. Sweet ◽  
Audrey R. Tyrka ◽  
...  
Keyword(s):  
Functional Connectivity ◽  
Resting State ◽  
Life Stress ◽  
Early Life ◽  
Early Life Stress ◽  
Regional Homogeneity ◽  
Resting State Functional Connectivity

scholarly journals Maternal Depression, Child Temperament, and Early-Life Stress Predict Never-Depressed Preadolescents’ Functional Connectivity During a Negative-Mood Induction

2021 ◽  
pp. 216770262110164
Author(s):  
Pan Liu ◽  
Matthew R. J. Vandermeer ◽  
Ola Mohamed Ali ◽  
Andrew R. Daoust ◽  
Marc F. Joanisse ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Functional Connectivity ◽  
Maternal Depression ◽  
Life Stress ◽  
Early Life ◽  
Negative Emotion ◽  
Negative Mood ◽  
Emotion Processing ◽  
Early Life Stress ◽  
Cingulate Cortex

Understanding the development of depression can inform etiology and prevention/intervention. Maternal depression and maladaptive patterns of temperament (e.g., low positive emotionality [PE] or high negative emotionality, especially sadness) are known to predict depression. Although it is unclear how these risks cause depression, altered functional connectivity (FC) during negative-emotion processing may play an important role. We investigated whether maternal depression and age-3 emotionality predicted FC during negative mood reactivity in never-depressed preadolescents and whether these relationships were augmented by early-life stress. Maternal depression predicted decreased medial prefrontal cortex (mPFC)–amygdala and mPFC–insula FC but increased mPFC–posterior cingulate cortex (PCC) FC. PE predicted increased dorsolateral prefrontal cortex–amygdala FC, whereas sadness predicted increased PCC-based FC in insula, orbitofrontal cortex, and anterior cingulate cortex (ACC). Sadness was more strongly associated with PCC–insula and PCC–ACC FC as early stress increased. Findings indicate that early depression risks may be mediated by FC underlying negative-emotion processing.

Impact of early-life stress on the medial prefrontal cortex functions – a search for the pathomechanisms of anxiety and mood disorders

2013 ◽  
Vol 65 (6) ◽  
pp. 1462-1470 ◽  
Author(s):  
Agnieszka Chocyk ◽  
Iwona Majcher-Maślanka ◽  
Dorota Dudys ◽  
Aleksandra Przyborowska ◽  
Krzysztof Wędzony
Keyword(s):  
Prefrontal Cortex ◽  
Mood Disorders ◽  
Medial Prefrontal Cortex ◽  
Life Stress ◽  
Early Life ◽  
Early Life Stress

The effects of early life stress on the excitatory/inhibitory balance of the medial prefrontal cortex

2020 ◽  
Vol 379 ◽  
pp. 112306 ◽  
Author(s):  
Ken-ichi Ohta ◽  
Shingo Suzuki ◽  
Katsuhiko Warita ◽  
Kazunori Sumitani ◽  
Chiaki Tenkumo ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Medial Prefrontal Cortex ◽  
Life Stress ◽  
Early Life ◽  
Early Life Stress

scholarly journals SSRI administration reduces resting state functional connectivity in dorso-medial prefrontal cortex

2011 ◽  
Vol 16 (6) ◽  
pp. 592-594 ◽  
Author(s):  
C McCabe ◽  
Z Mishor ◽  
N Filippini ◽  
P J Cowen ◽  
M J Taylor ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Functional Connectivity ◽  
Medial Prefrontal Cortex ◽  
Resting State ◽  
Resting State Functional Connectivity
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