scholarly journals Blood pressure and glomerular filtration rate in youth with tuberous sclerosis complex

2022 ◽  
Author(s):  
Efthymia Vargiami ◽  
Stella Stabouli ◽  
Christina Sidira ◽  
Maria Kyriazi ◽  
Athanasia Anastasiou ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Tuberous Sclerosis ◽  
Tuberous Sclerosis Complex ◽  
Filtration Rate

scholarly journals Blood Pressure and Glomerular Filtration Rate in Youth With Tuberous Sclerosis Complex

2021 ◽  
Author(s):  
Efthymia Vargiami ◽  
Stella Stabouli ◽  
Christina Sidira ◽  
Maria Kyriazi ◽  
Athanasia Anastasiou ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Tuberous Sclerosis ◽  
Kidney Function ◽  
Tuberous Sclerosis Complex ◽  
Filtration Rate ◽  
Renal Involvement ◽  
Childhood And Adolescence ◽  
Renal Imaging

Abstract Background Renal involvement is very common in tuberous sclerosis complex (TSC) and is characterised by the development of angiomyolipoma and cysts. The aims of the present study were to assess kidney function and clinical features of renal involvement in TSC, including kidney function, and blood pressure (BP) levels in children, adolescents and young adults. Methods Non-selected patients with a definite diagnosis of TSC attending the paediatric neurology outpatient department of a tertiary hospital were included in a cross-sectional study. All participants had a renal imaging study within 6 months of ambulatory blood pressure (BP) and glomerular filtration rate (GFR) assessment. Data on demographics, history, genotype, kidney function at diagnosis and last imaging were collected. Results The median age of the patients was 15 years (IQR range 9 to18). 23.5% of the participants had ambulatory BP hypertension. Systolic BP levels correlated significantly with GFRDTPA values despite the absence of hyperfiltration. Greater increase in GFR from initial TSC diagnosis till the age of the assessment, resulted in higher GFR levels in childhood and adolescence in those that developed hypertension and possibly in those with angiomyolipoma or cysts. All patients with ambulatory BP hypertension had angiomyolipomas or cysts on renal imaging studies. Conclusions Hypertension may present with increased frequency in young patients with kidney disease associated with TSC. Routine ambulatory BP measurement could be part of the annual clinical assessment in patients with TSC.

scholarly journals The impact of renal angiomyolipoma on estimated glomerular filtration rate in patients with tuberous sclerosis complex

2016 ◽  
Vol 36 (5) ◽  
pp. 356-363
Author(s):  
Raouf Seyam ◽  
Waleed Al Khudair ◽  
Said A. Kattan ◽  
Mohammed Faihan Al Otaibi ◽  
Fawaz Skaff ◽  
...  
Keyword(s):  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Tuberous Sclerosis ◽  
Tuberous Sclerosis Complex ◽  
Filtration Rate ◽  
Estimated Glomerular Filtration Rate ◽  
Renal Angiomyolipoma ◽  
The Impact

scholarly journals Long-term follow-up of blood pressure and glomerular filtration rate in patients with a solitary functioning kidney: a comparison between Wilms tumor survivors and nephrectomy for other reasons

2015 ◽  
Vol 31 (3) ◽  
pp. 435-441 ◽  
Author(s):  
Annelies M. C. Mavinkurve-Groothuis ◽  
Frank van de Kracht ◽  
Rik Westland ◽  
Joanna A. E. van Wijk ◽  
Jacqueline J. Loonen ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Filtration Rate ◽  
Wilms Tumor ◽  
Solitary Functioning Kidney ◽  
Long Term Follow Up ◽  
Functioning Kidney
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