Defective DNA repair genes in a primary culture of human renal cell carcinoma

2000 ◽  
Vol 126 (4) ◽  
pp. 185-190 ◽  
Author(s):  
Huan-Chao Chen ◽  
Nandan Bhattacharyya ◽  
Liming Wang ◽  
Anthony J. Recupero ◽  
Eric A. Klein ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Dna Repair ◽  
Cell Carcinoma ◽  
Primary Culture ◽  
Renal Cell ◽  
Dna Repair Genes ◽  
Human Renal Cell Carcinoma ◽  
Defective Dna Repair ◽  
Repair Genes

scholarly journals The Clinical Significance of DNA Damage Repair Signatures in Clear Cell Renal Cell Carcinoma

2021 ◽  
Vol 11 ◽  
Author(s):  
Ergang Guo ◽  
Cheng Wu ◽  
Jun Ming ◽  
Wei Zhang ◽  
Linli Zhang ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Dna Damage ◽  
Dna Repair ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Clear Cell ◽  
Dna Repair Genes ◽  
Cell Renal Cell Carcinoma ◽  
Damage Repair ◽  
Repair Genes

DNA damage repair plays an important role in cancer’s initiation and progression, and in therapeutic resistance. The prognostic potential of damage repair indicators was studied in the case of clear cell renal cell carcinoma (ccRCC). Gene expression profiles of the disease were downloaded from cancer genome databases and gene ontology was applied to the DNA repair-related genes. Twenty-six differentially expressed DNA repair genes were identified, and regression analysis was used to identify those with prognostic potential and to construct a risk model. The model accurately predicted patient outcomes and distinguished among patients with different expression levels of immune evasion genes. The data indicate that DNA repair genes can be valuable for predicting the progression of clear cell renal cell carcinoma and the clinical benefits of immunotherapy.

Polymorphisms of DNA repair genes are associated with renal cell carcinoma

2006 ◽  
Vol 342 (4) ◽  
pp. 1058-1062 ◽  
Author(s):  
Hiroshi Hirata ◽  
Yuji Hinoda ◽  
Hideyasu Matsuyama ◽  
Yuichiro Tanaka ◽  
Naoko Okayama ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Dna Repair ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Dna Repair Genes ◽  
Repair Genes

1008: Expression of Cyclooxygenase-2 (COX-2) in Human Renal Cell Carcinoma (RCCA)

2004 ◽  
Vol 171 (4S) ◽  
pp. 266-267
Author(s):  
Sean McLaughlin ◽  
Eric Wallen ◽  
William K. Funkhouser ◽  
Raj S. Pruthi
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Cyclooxygenase 2 ◽  
Human Renal Cell Carcinoma ◽  
Cox 2

75 CURCUMIN TARGETS RELA (P65) STABILITY TO INHIBIT CONSTITUTIVE NF-KAPPA B ACTIVATION AND INDUCES APOPTOSIS IN HUMAN RENAL CELL CARCINOMA

2010 ◽  
Vol 183 (4S) ◽  
Author(s):  
Jeong Seok Hwa ◽  
Fernando J. Kim ◽  
Binod Kumar ◽  
Sweaty Koul ◽  
Randall Meacham ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Nf Kappa B ◽  
Human Renal Cell Carcinoma

scholarly journals Progression of Human Renal Cell Carcinoma via Inhibition of RhoA-ROCK Axis by PARG1

2017 ◽  
Vol 10 (2) ◽  
pp. 142-152 ◽  
Author(s):  
Junichiro Miyazaki ◽  
Keiichi Ito ◽  
Tomonobu Fujita ◽  
Yuriko Matsuzaki ◽  
Takako Asano ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Human Renal Cell Carcinoma
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