Macroscopic hematuria, facing an uncommon disease: Questions

Moyamoya is an uncommon disease that presents with stenoocclusion of the major vasculature at the base of the brain and associated collateral vessel formation. Many pediatric patients with moyamoya present with transient ischemic attacks or complete occlusions. The authors report the case of a 9-year-old girl who presented with posterior fossa hemorrhage and was treated with an emergency suboccipital craniotomy for evacuation. After emergency surgery, an angiogram was performed, and the patient was diagnosed with moyamoya disease. Six months later, the patient was treated for moyamoya using direct and indirect revascularization; after surgery there was excellent vascularization in both regions of the bypass and no further progression of moyamoya changes. This case illustrates a rare example of intracerebral hemorrhage associated with moyamoya changes in the posterior vascularization in a pediatric patient and subsequent use of direct and indirect revascularization to reduce the risk of future hemorrhage and moyamoya progression.

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Macroscopic hematuria in a child with portal hypertension: Questions

Pediatric Nephrology ◽

10.1007/s00467-021-05161-1 ◽

2021 ◽

Author(s):

Emre Leventoğlu ◽

Bahar Büyükkaragöz ◽

Bahriye Uzun Kenan ◽

Sinan Sarı ◽

Sevcan A. Bakkaloglu

Keyword(s):

Portal Hypertension ◽

Macroscopic Hematuria

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HUNTINGTON'S CHOREA IN QUEENSLAND A NOT UNCOMMON DISEASE

The Medical Journal of Australia ◽

10.5694/j.1326-5377.1972.tb46796.x ◽

1972 ◽

Vol 1 (7) ◽

pp. 299-307 ◽

Cited By ~ 17

Author(s):

D. C. Wallace

Keyword(s):

Huntington's Chorea ◽

Uncommon Disease

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The Role of Radiation Therapy in the Management of Primary Non-Hodgkin Lymphomas of the Central Nervous System: Clinical Study of 10 Cases

Tumori Journal ◽

10.1177/030089168607200605 ◽

1986 ◽

Vol 72 (6) ◽

pp. 565-573 ◽

Cited By ~ 9

Author(s):

Adriano Di Marco ◽

Luisa Rosta ◽

Franco Campostrini ◽

Andrea Bonetti ◽

Mario Palazzi ◽

...

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Radiation Therapy ◽

Whole Brain Irradiation ◽

Brain Irradiation ◽

Non Hodgkin Lymphoma ◽

Uncommon Disease ◽

The Central Nervous System ◽

Disseminated Disease ◽

Clinical Conditions

A series of 10 patients with a primary non-Hodgkin lymphoma of the central nervous system were observed and treated by the authors. All were diagnosed after a pathologic examination of the surgical material; the lesions were supratentorial in all cases and unifocal in 9. In every case radiation therapy improved clinical conditions and in most cases even radiologic features of the patients. Four patients were alive and without evidence of disease many months after therapy. Four patients died with a relapse in the central nervous system; 3 of them had disseminated disease at the time of death. Two patients died for an unknown cause. Radiation therapy was performed with 60Co source with 2 opposed portals and the whole brain irradiation technique in all cases but 2. Doses ranged from 35 to 54 Gy. The recent literature on this uncommon disease and the most adequate therapeutic possibilities of radiation therapy and chemotherapy, or both, are discussed.

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Essential role of using virtual pyeloscopy in the diagnosis of small satellite renal pelvic tumour in solitary kidney patient

Canadian Urological Association Journal ◽

10.5489/cuaj.27 ◽

2012 ◽

Vol 6 (5) ◽

Author(s):

Pal Bata ◽

David Laszlo Tarnoki ◽

Adam Domonkos Tarnoki ◽

Zsolt Domjan ◽

Istvan Buzogany ◽

...

Keyword(s):

Multidetector Ct ◽

Cell Cancer ◽

Transitional Cell ◽

Solitary Kidney ◽

Tumour Resection ◽

Small Satellite ◽

Macroscopic Hematuria ◽

Three Phase ◽

Transitional Cell Cancer ◽

Organ Sparing

Virtual pyeloscopy (VP) plays an important role in the organ-sparing nephroscopic tumour resection and traditional pole resection, especially when a fibreoptic ureteroscopic examination cannot be performed. A 67-year-old man developed macroscopic hematuria. Abdominal computed tomography (CT) and cystoscopy revealed a lower calix renal stone and a 20-mm lower pyelon mass suggesting transitional cell cancer. An additional small satellite lesion in the pelvico-ureteral junction was supposedly present. Three-phase MultiDetector CT with VP showed a solitary 3 to 4-mm renal pelvic lesion beyond the known calix stone and lower pole mass. In our case, VP played an important role in the organ-sparing nephroscopic tumour resection and traditional pole resection.

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Flexible Cystoscopy in the Setting of Macroscopic Hematuria: Do the Findings Justify Its Use?

Urologia Internationalis ◽

10.1159/000517374 ◽

2021 ◽

pp. 1-7

Author(s):

Reuben Ben-David ◽

Samuel Morgan ◽

Ziv Savin ◽

Snir Dekalo ◽

Mario Sofer ◽

...

Keyword(s):

Outpatient Setting ◽

Study Cohort ◽

Gross Hematuria ◽

Diagnostic Ability ◽

Complete Evaluation ◽

Macroscopic Hematuria ◽

Flexible Cystoscopy ◽

Univariate Analyses ◽

Prompt Diagnosis

Background: Patients hospitalized due to gross hematuria frequently complete evaluation in the outpatient setting. The use of office flexible cystoscopy during hospitalization may lead to prompt diagnosis and treatment but can be limited due to low visualization and artifacts that can hamper diagnostic ability. Objective: The objective of this study was to assess flexible cystoscopy findings and yield performed in patients hospitalized due to gross hematuria. Methods: Medical records of patients who underwent flexible cystoscopy while hospitalized during September 2018–December 2019 were reviewed. Cystoscopic findings were categorized into (1) suspicious mass in the bladder or prostate, (2) nonsuspicious changes in the bladder, and (3) nondiagnostic exam. Descriptive statistics were used to report the clinical characteristics of the study cohort and the findings of cystoscopy. Univariate logistic regression analyses were used to identify predictors of malignant findings. Results: The study cohort consisted of 69 patients (median age of 76 years). Initial cystoscopy findings were suspicious for malignancy in 26/69 patients (38%), nonsuspicious for malignancy in 34/69 patients (49%), and nondiagnostic in 9/69 patients (13%). The median follow-up time was 9 months (range 4–14 months). Twenty patients (29%) were diagnosed with malignancy (sensitivity of 75% and specificity of 78%). The procedure led to either diagnosis or treatment of 39 patients (57%). However, in 30 patients (43%), the initial cystoscopy did not aid in the diagnosis, led to misdiagnoses, or required a follow-up cystoscopy. On univariate analyses, none of the precystoscopy variables were predictive of bladder malignancy. Conclusion: Flexible cystoscopy in the setting of acute hematuria requiring hospitalization did not lead to diagnosis or treatment in over 40% of cases. In this setting, consideration should be given to performing an upfront cystoscopy under anesthesia.

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The Case | Macroscopic hematuria in a young woman

Kidney International ◽

10.1016/j.kint.2016.05.010 ◽

2016 ◽

Vol 90 (5) ◽

pp. 1135-1136

Author(s):

Alain Meyrier

Keyword(s):

Young Woman ◽

Macroscopic Hematuria

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Azathioprine in Combination with Steroids in the Treatment of Autoimmune Inner-Ear Disease

Journal of International Medical Research ◽

10.1177/030006059302100404 ◽

1993 ◽

Vol 21 (4) ◽

pp. 192-196 ◽

Cited By ~ 35

Author(s):

Aytac Saraçaydin ◽

Sedat Katircioğlu ◽

Sami Katircioğlu ◽

M Can Karatay

Keyword(s):

Hearing Loss ◽

Sensorineural Hearing Loss ◽

Inner Ear ◽

Sensorineural Deafness ◽

Sensorineural Hearing ◽

Once Daily ◽

Uncommon Disease ◽

Inner Ear Disease ◽

Pure Tones ◽

Autoimmune Inner Ear Disease

A total of twelve patients with a relatively uncommon form of progressive sensorineural deafness (autoimmune innerear disease) were treated orally with 1 mg/kg azathioprine, once daily, and with 30 mg prednisolone, every other day, for 4 weeks. Statistically significant increases in the ability to hear pure tones or in discrimination on audiometry took place in 10/12 patients. This condition was initially described as ‘sensorineural hearing loss', but it is now clear that the term ‘autoimmune inner-ear disease’ is more appropriate since the vestibular compartment as well as the cochlear compartment is involved. This relatively uncommon disease is one of the few forms of sensorineural deafness that can be successfully treated.

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Inflammatory Myofibroblastic Tumor of the Bladder: 2 Rare Cases Managed with Laparoscopic Partial Cystectomy

Case Reports in Urology ◽

10.1155/2016/4976150 ◽

2016 ◽

Vol 2016 ◽

pp. 1-3 ◽

Cited By ~ 1

Author(s):

Sofia Santos Lopes ◽

Andrea Furtado ◽

Rita Oliveira ◽

Ana Cebola ◽

Bruno Graça ◽

...

Keyword(s):

Inflammatory Myofibroblastic Tumor ◽

Clinical Presentation ◽

Treatment Approach ◽

Pathological Condition ◽

Partial Cystectomy ◽

Pathological Features ◽

Macroscopic Hematuria ◽

Voiding Symptoms ◽

First Case

Two cases of inflammatory myofibroblastic tumor (IMT) of the bladder are reported here. Both patients were male and presented with macroscopic hematuria; in the first case terminal hematuria was associated with irritative voiding symptoms. The second case was a smoker with hematuria unresponsive to medical treatment and anemia. Clinical presentation, pathological features, treatment, and prognosis are discussed. Due to rarity of this pathological condition, there are no guidelines concerning treatment and follow-up. We present our follow-up scheme and highlight the use of laparoscopic partial cystectomy as a successful treatment approach.

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