scholarly journals Beef cattle body temperature during climatic stress: a genome-wide association study

2013 ◽  
Vol 58 (7) ◽  
pp. 1665-1672 ◽  
Author(s):  
Jeremy T. Howard ◽  
Stephen D. Kachman ◽  
Warren M. Snelling ◽  
E. John Pollak ◽  
Daniel C. Ciobanu ◽  
...  
Keyword(s):  
Body Temperature ◽  
Beef Cattle ◽  
Association Study ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
Climatic Stress ◽  
Genome Wide ◽  
A Genome

scholarly journals Genome-wide association study identifies loci and candidate genes for internal organ weights in Simmental beef cattle

2018 ◽  
Vol 50 (7) ◽  
pp. 523-531 ◽  
Author(s):  
Bingxing An ◽  
Jiangwei Xia ◽  
Tianpeng Chang ◽  
Xiaoqiao Wang ◽  
Jian Miao ◽  
...  
Keyword(s):  
Beef Cattle ◽  
Association Study ◽  
Genome Wide Association Study ◽  
Snp Array ◽  
Genome Wide Association ◽  
Heart Weight ◽  
Spleen Weight ◽  
Internal Organs ◽  
Genome Wide ◽  
A Genome

Cattle internal organs as accessible raw materials have a long history of being widely used in beef processing, feed and pharmaceutical industry. These traits not only are of economic interest to breeders, but they are intrinsically linked to many valuable traits, such as growth, health, and productivity. Using the Illumina Bovine HD 770K SNP array, we performed a genome-wide association study for heart weight, liver weight, spleen weight, lung weight, and kidney weight in 1,217 Simmental cattle. In our research, 38 significant single nucleotide polymorphisms (SNPs) ( P < 1.49 × 10−6) were identified for five internal organ weight traits. These SNPs are within or near 13 genes, and some of them have been reported previously, including NDUFAF4, LCORL, BT.94996, SLIT2, FAM184B, LAP3, BBS12, MECOM, CD300LF, HSD17B3, TLR4, MXI1, and MB21D2. In addition, we detected four haplotype blocks on BTA6 containing 18 significant SNPs associated with spleen weight. Our results offer worthy insights into understanding the genetic mechanisms of internal organs' development, with potential application in breeding programs of Simmental beef cattle.

A genome-wide association study suggests several novel candidate genes for carcass traits in Chinese Simmental beef cattle

2018 ◽  
Vol 49 (4) ◽  
pp. 312-316 ◽  
Author(s):  
T. Chang ◽  
J. Xia ◽  
L. Xu ◽  
X. Wang ◽  
B. Zhu ◽  
...  
Keyword(s):  
Beef Cattle ◽  
Association Study ◽  
Candidate Genes ◽  
Genome Wide Association Study ◽  
Carcass Traits ◽  
Genome Wide Association ◽  
Genome Wide ◽  
A Genome

PSXI-7 Genomic analysis of heterosis in a composite beef cattle breed

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 244-244
Author(s):  
El Hamidi Hay ◽  
Andrew Roberts
Keyword(s):  
Birth Weight ◽  
Beef Cattle ◽  
Association Study ◽  
Genome Wide Association Study ◽  
Growth Traits ◽  
Snp Markers ◽  
Genome Wide Association ◽  
Weaning Weight ◽  
Genome Wide ◽  
A Genome

Abstract Crossbreeding is widely used in the beef cattle industry to exploit benefits of heterosis. This study evaluated the effects of heterozygosity on growth traits in an Angus x Hereford cross population. Moreover, a genome wide association study was conducted to detect regions in the genome with significant dominance effects on growth traits contributing to heterosis. A total of 1,530 animals, comprised of pure Line 1 Hereford, Angus and Angus x Line 1 Hereford crosses, were evaluated. Phenotypes included birth weight, weaning weight and yearling weight. All animals were genotyped with GeneSeek GGP LD 50k. Effects of genomic heterozygosity on growth traits were estimated. These effects were -0.76 kg (P &lt; 0.001), 4.67 kg (P &lt; 0.0001), 42.39 kg (P &lt; 0.02) on birth weight, weaning weight and yearling weight respectively. A genome wide association study revealed several SNP markers with significant heterotic effects associated with birth weight, weaning weight and yearling weight. These SNP markers were located on chromosomes 1, 2, 14, 19, 13 and 12. Genes in these regions were reported to be involved in growth and other important physiological mechanisms. Our study revealed several regions associated with dominance effects and contributing to heterosis. These results could be beneficial in optimizing crossbreeding.

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