Epidemiological survey of tick-borne encephalitis virus and Anaplasma phagocytophilum co-infections in patients from regions of the Czech Republic endemic for tick-borne diseases

2007 ◽  
Vol 119 (17-18) ◽  
pp. 538-543 ◽  
Author(s):  
Petr Zeman ◽  
Petr Pazdiora ◽  
Vaclav Chmelik ◽  
Jiri Januska ◽  
Karel Sedivy ◽  
...  
2011 ◽  
Vol 92 (8) ◽  
pp. 1906-1916 ◽  
Author(s):  
M. Weidmann ◽  
D. Růžek ◽  
K. Křivanec ◽  
G. Zöller ◽  
S. Essbauer ◽  
...  

Tick-borne encephalitis virus (TBEV) is the most important arboviral agent causing disease of the central nervous system in central Europe. In this study, 61 TBEV E gene sequences derived from 48 isolates from the Czech Republic, and four isolates and nine TBEV strains detected in ticks from Germany, covering more than half a century from 1954 to 2009, were sequenced and subjected to phylogenetic and Bayesian phylodynamic analysis to determine the phylogeography of TBEV in central Europe. The general Eurasian continental east-to-west pattern of the spread of TBEV was confirmed at the regional level but is interlaced with spreading that arises because of local geography and anthropogenic influence. This spread is reflected by the disease pattern in the Czech Republic that has been observed since 1991. The overall evolutionary rate was estimated to be approximately 8×10−4 substitutions per nucleotide per year. The analysis of the TBEV E genes of 11 strains isolated at one natural focus in Žďár Kaplice proved for the first time that TBEV is indeed subject to local evolution.


2013 ◽  
Vol 94 (9) ◽  
pp. 2129-2139 ◽  
Author(s):  
Manfred Weidmann ◽  
Stefan Frey ◽  
Caio C. M. Freire ◽  
Sandra Essbauer ◽  
Daniel Růžek ◽  
...  

In order to obtain a better understanding of tick-borne encephalitis virus (TBEV) strain movements in central Europe the E gene sequences of 102 TBEV strains collected from 1953 to 2011 at 38 sites in the Czech Republic, Slovakia, Austria and Germany were determined. Bayesian analysis suggests a 350-year history of evolution and spread in central Europe of two main lineages, A and B. In contrast to the east to west spread at the Eurasian continent level, local central European spreading patterns suggest historic west to east spread followed by more recent east to west spread. The phylogenetic and network analyses indicate TBEV ingressions from the Czech Republic and Slovakia into Germany via landscape features (Danube river system), biogenic factors (birds, red deer) and anthropogenic factors. The identification of endemic foci showing local genetic diversity is of paramount importance to the field as these will be a prerequisite for in-depth analysis of focal TBEV maintenance and long-distance TBEV spread.


2006 ◽  
Vol 6 (4) ◽  
pp. 379-381 ◽  
Author(s):  
Manfred Weidmann ◽  
Peter Schmidt ◽  
Frank T. Hufert ◽  
Karel Krivanec ◽  
Hermann Meyer

2014 ◽  
Vol 47 (1) ◽  
pp. 52-56 ◽  
Author(s):  
Reidar Hjetland ◽  
Anna J. Henningsson ◽  
Kirsti Vainio ◽  
Susanne G. Dudman ◽  
Nils Grude ◽  
...  

2019 ◽  
Vol 10 (1) ◽  
pp. 115-123 ◽  
Author(s):  
Nanna Skaarup Andersen ◽  
Sanne Løkkegaard Larsen ◽  
Carsten Riis Olesen ◽  
Karin Stiasny ◽  
Hans Jørn Kolmos ◽  
...  

PLoS ONE ◽  
2019 ◽  
Vol 14 (12) ◽  
pp. e0226836 ◽  
Author(s):  
Katrine M. Paulsen ◽  
Erik G. Granquist ◽  
Wenche Okstad ◽  
Rose Vikse ◽  
Karin Stiasny ◽  
...  

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