Diagnostic-driven antifungal approach in neutropenic patients at high risk for chronic disseminated candidiasis: preliminary observations on the role of 1,3-β-D-glucan antigenemia and multiphasic contrast-enhanced computed tomography

Pre-procedural imaging is essential for successful planning and performance of several cardiac interventions. For this purpose, contrast-enhanced computed tomography (CT) imaging—owing to its high and isotropic spatial resolution as well as fast volume coverage—is gaining increasing importance. Cardiac CT offers high-resolution morphological and functional imaging of cardiac structures which is valuable for a variety of structural heart disease interventions, electrophysiology procedures, and coronary interventions. Over the last decade, the widened spectrum of transcatheter cardiac interventions has been associated with widespread acknowledgment that CT is particularly useful for pre-interventional imaging and increasing implementation in clinical routine. In this chapter, the role of cardiac CT for the guidance of coronary as well as non-coronary cardiac interventions is described.

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Computed tomography for cardiac interventions

ESC CardioMed ◽

10.1093/med/9780198784906.003.0118 ◽

2018 ◽

pp. 565-572

Author(s):

Mohamed Marwan ◽

Stephan Achenbach

Keyword(s):

Computed Tomography ◽

Heart Disease ◽

Cardiac Ct ◽

Structural Heart Disease ◽

Interventional Imaging ◽

Contrast Enhanced ◽

And Performance ◽

Enhanced Computed Tomography ◽

Contrast Enhanced Computed Tomography

Pre-procedural imaging is essential for successful planning and performance of several cardiac interventions. For this purpose, contrast-enhanced computed tomography (CT) imaging—owing to its high and isotropic spatial resolution as well as fast volume coverage—is gaining increasing importance. Cardiac CT offers high-resolution morphological and functional imaging of cardiac structures which is valuable for a variety of structural heart disease interventions, electrophysiology procedures, and coronary interventions. Over the last decade, the widened spectrum of transcatheter cardiac interventions has been associated with widespread acknowledgment that CT is particularly useful for pre-interventional imaging and increasing implementation in clinical routine. In this chapter, the role of cardiac CT for the guidance of coronary as well as non-coronary cardiac interventions is described.

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Prognostic Predicting Role of Contrast-Enhanced Computed Tomography for Locally Advanced Pancreatic Adenocarcinoma

BioMed Research International ◽

10.1155/2019/1356264 ◽

2019 ◽

Vol 2019 ◽

pp. 1-9

Author(s):

Chien-shan Cheng ◽

Wei Liu ◽

Liangping Zhou ◽

Wei Tang ◽

Ailing Zhong ◽

...

Keyword(s):

Computed Tomography ◽

Pancreatic Adenocarcinoma ◽

Locally Advanced ◽

Tumour Volume ◽

Contrast Enhanced ◽

Locally Advanced Pancreatic Adenocarcinoma ◽

Enhanced Computed Tomography ◽

Contrast Enhanced Computed Tomography ◽

Advanced Pancreatic Adenocarcinoma

Introduction. Contrast-enhanced computed tomography (CECT) imaging is commonly used to assess pancreatic adenocarcinoma (PAC). However, the value of semiquantitative and quantitative assessments of CECT parameters used to predict survival in PAC remains unknown. This study aims to investigate the prognostic role of pretreatment CECT imaging in patients with locally advanced pancreatic adenocarcinoma (LAPAC). Materials and Methods. From June 2013 to May 2017, eighty-six newly diagnosed patients with pathologically and radiologically confirmed LAPAC were retrospectively recruited. All patients were evaluated by CECT and experienced gemcitabine-based chemotherapy. The relationship between overall survival (OS) and clinical factors including age, sex, serum carbohydrate antigen 19-9 value, and CECT findings (including tumour location, tumour volume, peripancreatic involvement, blood vessel involvement, tumour enhanced rate, and distance liver metastasis) was determined using Cox proportional hazard regression models, and a nomogram was constructed for the prediction of 1- and 1.5-year survival rates of patients with LAPAC. Results. On univariate analysis, patients who had a tumour enhanced rate (TER) less than 80.465% and those who had a TER ≥ 80.465% are with a 3.587-fold increase in OS (p<0.001). After multivariate Cox regression, a nomogram was established based on a new model containing the predictive variables of high Ca19-9 level, higher clinical stages, larger tumour volume, the presence of peripancreatic involvement, and liver metastases. The model displayed good accuracy in predicting OS with a C-index of 0.614. The calibration plots also showed a good discrimination and calibration of the nomogram between the predicted and observed survival probabilities. Conclusion. Our results showed that TER can be used to predict survival in LAPAC, and we developed a nomogram for determining the prognosis of patients with LAPAC. However, the purposed nomogram still requires external data verification in future applications.

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