Inter-rater reliability in performance status assessment among healthcare professionals: an updated systematic review and meta-analysis

2020 ◽  
Vol 28 (5) ◽  
pp. 2071-2078 ◽  
Author(s):  
Ronald Chow ◽  
Eduardo Bruera ◽  
Jennifer S. Temel ◽  
Monica Krishnan ◽  
James Im ◽  
...  
Keyword(s):  
Systematic Review ◽  
Healthcare Professionals ◽  
Meta Analysis ◽  
Performance Status ◽  
Rater Reliability ◽  
Status Assessment

Inter-rater reliability in performance status assessment among health care professionals: a systematic review

2016 ◽  
Vol 5 (2) ◽  
pp. 83-92 ◽  
Author(s):  
Ronald Chow ◽  
Nicholas Chiu ◽  
Eduardo Bruera ◽  
Monica Krishnan ◽  
Leonard Chiu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Health Care ◽  
Health Care Professionals ◽  
Performance Status ◽  
Rater Reliability ◽  
Status Assessment

scholarly journals Diagnostic Test Accuracy of the 4AT for Delirium Detection: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 17 (20) ◽  
pp. 7515 ◽  
Author(s):  
Eunhye Jeong ◽  
Jinkyung Park ◽  
Juneyoung Lee
Keyword(s):  
Systematic Review ◽  
Diagnostic Test ◽  
Healthcare Professionals ◽  
Meta Analysis ◽  
Diagnostic Test Accuracy ◽  
Test Accuracy ◽  
Summary Receiver Operating Characteristic ◽  
Bivariate Model ◽  
Data Synthesis

Under-recognition of delirium is an international problem. For the early detection of delirium, a feasible and valid screening tool for healthcare professionals is needed. This study aimed to present a scientific reason for using the 4 ‘A’s Test (4AT) through a systematic review and meta-analysis of studies on the diagnostic test accuracy. We systematically searched articles in the EMBASE, MEDLINE, CINAHL, and PsycINFO databases and selected relevant articles on the basis of the predefined inclusion criteria. The quality of the included articles was evaluated using the Quality Assessment of the Diagnostic Accuracy Studies-2 tool. We estimated the pooled values of diagnostic test accuracy by employing the bivariate model and the hierarchical summary receiver operating characteristic (HSROC) model in data synthesis. A total of 3729 patients of 13 studies were included in the analysis. The pooled estimates of sensitivity and specificity of the 4AT were 81.5% (95% confidence interval: 70.7%, 89.0%) and 87.5% (79.5%, 92.7%), respectively. Given the 4AT’s evidence of accuracy and practicality, we suggest healthcare professionals to utilize this tool for routine screening of delirium. However, for detecting delirium in the dementia population, further work is required to evaluate the 4AT with other cut-off points or scoring methods in order for it to be more sensitive and specific.

scholarly journals Efficacy and Safety of Brucea javanica Oil Emulsion Injection in the Treatment of Gastric Cancer: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 8 ◽  
Author(s):  
Xinmiao Wang ◽  
Heping Wang ◽  
Luchang Cao ◽  
Jingyuan Wu ◽  
Taicheng Lu ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Systematic Review ◽  
Conventional Therapy ◽  
Meta Analysis ◽  
Performance Status ◽  
Biomedical Literature ◽  
Therapeutic Effects ◽  
Efficacy And Safety ◽  
Oil Emulsion ◽  
Brucea Javanica

Background: Gastric cancer (GC) is one of the most common digestive tract cancers and ranks fifth in the incidence of malignant tumors worldwide. Brucea javanica oil emulsion injection (BJOEI), a Chinese patent medicine extracted from Brucea javanica (Yadanzi in Chinese Pinyin), is widely used as an adjuvant treatment for GC in China. This systematic review and meta-analysis aimed to evaluate the available data on the efficacy and safety of BJOEI in the treatment of GC and assess the quality of the synthesized evidence.Methods: A comprehensive search was performed on PubMed, EMBASE, CENTRAL, Web of Science, Chinese Biomedical Literature Database (CBM), China National Knowledge Infrastructure (CNKI), Wanfang database and Chinese Scientific Journals Database (VIP database), and other potential resources, such as the Chinese Clinical Trial Registry (ChiCTR) and ClinicalTrials.gov from their inception to July 31, 2021. Randomized controlled trials (RCTs) comparing the therapeutic effects of BJOEI combined with conventional therapy to those of conventional therapy alone were included. We used RevMan 5.3 for data analysis and quality evaluation of the included studies and assessed the evidence quality based on the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) criteria.Results: Eighteen RCTs involving 1,210 patients were included, and the meta-analysis results demonstrated that compared with the control group (conventional therapy), the experimental group (BJOEI combined with conventional therapy) showed a significantly improved overall response rate (ORR) (risk ratio [RR] = 1.52, 95% CI: 1.36–1.69, P < 0.00001), clinical benefit rate (CBR) (RR = 1.17, 95% CI: 1.11–1.23, P < 0.00001), performance status (RR = 1.72, 95% CI: 1.46–2.01, P < 0.00001), and reduced incidence of the following adverse drug reactions (ADRs): neutropenia, leukopenia, nausea and vomiting, diarrhea, liver damage, hand-foot syndrome, and peripheral sensory nerve toxicity. Subgroup analysis showed that the BJOEI intervention could significantly improve the ORR and CBR in patients with GC when combined with FOLFOX4, XELOX, and other chemotherapeutics.Conclusion: The evidence presented in this study supports the fact that BJOEI combined with conventional chemotherapy provides a statistically significant and clinically important effect in the improvement of ORR, CBR, performance status, and ADR reduction in patients with GC. To further support this conclusion, more rigorously designed, large-scale, and multicenter RCTs are needed in the future.

scholarly journals Risk Factors for Delirium in the Palliative Care Population: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 12 ◽  
Author(s):  
Duan Guo ◽  
Taiping Lin ◽  
Chuanyao Deng ◽  
Yuxia Zheng ◽  
Langli Gao ◽  
...  
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Palliative Care ◽  
Group Performance ◽  
Meta Analysis ◽  
Performance Status ◽  
Eastern Cooperative Oncology Group ◽  
Individual Risk ◽  
Case Control Studies

Objective: Delirium is common and highly distressing for the palliative care population. Until now, no study has systematically reviewed the risk factors of delirium in the palliative care population. Therefore, we performed a systematic review and meta-analysis to evaluate delirium risk factors among individuals receiving palliative care.Methods: We systematically searched PubMed, Medline, Embase, and Cochrane database to identify relevant observational studies from database inception to June 2021. The methodological quality of the eligible studies was assessed by the Newcastle Ottawa Scale. We estimated the pooled adjusted odds ratio (aOR) for individual risk factors using the inverse variance method.Results: Nine studies were included in the review (five prospective cohort studies, three retrospective case-control studies and one retrospective cross-section study). In pooled analyses, older age (aOR: 1.02, 95% CI: 1.01–1.04, I2 = 37%), male sex (aOR:1.80, 95% CI: 1.37–2.36, I2 = 7%), hypoxia (aOR: 0.87, 95% CI: 0.77–0.99, I2 = 0%), dehydration (aOR: 3.22, 95%CI: 1.75–5.94, I2 = 18%), cachexia (aOR:3.40, 95% CI: 1.69–6.85, I2 = 0%), opioid use (aOR: 2.49, 95%CI: 1.39–4.44, I2 = 0%), anticholinergic burden (aOR: 1.18, 95% CI: 1.07–1.30, I2 = 9%) and Eastern Cooperative Oncology Group Performance Status (aOR: 2.54, 95% CI: 1.56–4.14, I2 = 21%) were statistically significantly associated with delirium.Conclusion: The risk factors identified in our review can help to highlight the palliative care population at high risk of delirium. Appropriate strategies should be implemented to prevent delirium and improve the quality of palliative care services.

Prevalence of sleep disturbances in Chinese healthcare professionals: a systematic review and meta-analysis

2020 ◽  
Vol 67 ◽  
pp. 258-266 ◽  
Author(s):  
Dan Qiu ◽  
Yu Yu ◽  
Rui-Qi Li ◽  
Yi-Lu Li ◽  
Shui-Yuan Xiao
Keyword(s):  
Systematic Review ◽  
Sleep Disturbances ◽  
Healthcare Professionals ◽  
Meta Analysis

Healthcare professionals’ experiences and perspectives on using telehealth for home-based palliative care: a scoping review protocol (Preprint)

2021 ◽  
Author(s):  
Elias David Lundereng ◽  
Andrea Aparecida Goncalves Nes ◽  
Heidi Holmen ◽  
Anette Winger ◽  
Hilde Thygesen ◽  
...  
Keyword(s):  
Systematic Review ◽  
Palliative Care ◽  
Scoping Review ◽  
Healthcare Professionals ◽  
Meta Analysis ◽  
Eligibility Criteria ◽  
Hand Search ◽  
Home Based ◽  
Review Protocol ◽  
Analysis Protocol

BACKGROUND Telehealth seems feasible for use in home-based palliative care. However, acceptance among healthcare professionals is essential for the successful delivery of telehealth in practice. No scoping review has mapped the experiences and perspectives of healthcare professionals on the use of telehealth for home-based palliative care. OBJECTIVE To systematically map published studies on healthcare professionals’ experiences and perspectives on the use of telehealth in home-based palliative care. METHODS The proposed scoping review will employ the methodology of Arksey and O’Malley. This protocol is guided by the Preferred Reporting Items for Systematic review and Meta-Analysis Protocol (PRISMA-P). A systematic search was performed in Medical Literature Analysis and Retrieval System Online (MEDLINE), PsycINFO, Excerpta Medica Database (EMBASE), Cumulative Index to Nursing and Allied Health (CINAHL), Allied and Complementary Medicine (AMED) and Web of Science (WoS) for studies published between January 2000 to July 5, 2021. We will also hand search the reference lists of included papers to identify additional studies of relevance. The search will be updated in 2022. Pairs of authors will independently assess eligibility of studies and extract data. The two first stages of thematic synthesis will be used to thematically organize the data material. Since the scoping review methodology consists of reviewing and collecting data from publicly available materials, this study does not require ethics approval. RESULTS The database searches were performed on July 5, 2021 and the eligibility criteria were tested in July-August 2021. After removal of 2364 duplicates, the search yielded 2420 citations.We will screen titles, abstracts and full-text papers by fall 2021. Results are anticipated by September 2022. CONCLUSIONS A mapping of studies could identify research gaps regarding healthcare professionals’ experiences and perspectives on the use of telehealth in home-based palliative care and may determine the value and feasibility of conducting a full systematic review.

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