Predictors of health-related quality of life after completion of chemotherapy among Malaysian early-stage breast cancer survivors

2021 ◽  
Author(s):  
Syarifah Maisarah Syed Alwi ◽  
Vairavan Narayanan ◽  
Nur Aishah Mohd Taib ◽  
Normah Che Din
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Cancer Survivors ◽  
Breast Cancer Survivors ◽  
Early Stage ◽  
Early Stage Breast Cancer ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

scholarly journals Health-related quality of life of early-stage breast cancer patients after different radiotherapy regimens

2021 ◽  
Author(s):  
Daphne H. M. Jacobs ◽  
Ramona K. Charaghvandi ◽  
Nanda Horeweg ◽  
John H. Maduro ◽  
Gabrielle Speijer ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Early Stage ◽  
Early Stage Breast Cancer ◽  
Breast Irradiation ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Over Time

Abstract Purpose To evaluate and compare health-related quality of life (HRQL) of women with early-stage breast cancer (BC) treated with different radiotherapy (RT) regimens. Methods Data were collected from five prospective cohorts of BC patients treated with breast-conserving surgery and different RT regimens: intraoperative RT (IORT, 1 × 23.3 Gy; n = 267), external beam accelerated partial breast irradiation (EB-APBI, 10 × 3.85 Gy; n = 206), hypofractionated whole breast irradiation(hypo-WBI, 16 × 2.67 Gy; n = 375), hypo-WBI + boost(hypo-WBI-B, 21–26 × 2.67 Gy; n = 189), and simultaneous WBI + boost(WBI-B, 28 × 2.3 Gy; n = 475). Women ≥ 60 years with invasive/in situ carcinoma ≤ 30 mm, cN0 and pN0-1a were included. Validated EORTC QLQ-C30/BR23 questionnaires were used to asses HRQL. Multivariable linear regression models adjusted for confounding (age, comorbidity, pT, locoregional treatment, systemic therapy) were used to compare the impact of the RT regimens on HRQL at 12 and 24 months. Differences in HRQL over time (3–24 months) were evaluated using linear mixed models. Results There were no significant differences in HRQL at 12 months between groups except for breast symptoms which were better after IORT and EB-APBI compared to hypo-WBI at 12 months (p < 0.001). Over time, breast symptoms, fatigue, global health status and role functioning were significantly better after IORT and EB-APBI than hypo-WBI. At 24 months, HRQL was comparable in all groups. Conclusion In women with early-stage breast cancer, the radiotherapy regimen did not substantially influence long-term HRQL with the exception of breast symptoms. Breast symptoms are more common after WBI than after IORT or EB-APBI and improve slowly until no significant difference remains at 2 years posttreatment.

Health-Related Quality of Life in a Predictive Model for Mortality in Older Breast Cancer Survivors

2018 ◽  
Vol 66 (6) ◽  
pp. 1115-1122 ◽  
Author(s):  
Clark DuMontier ◽  
Kerri M. Clough-Gorr ◽  
Rebecca A. Silliman ◽  
Andreas E. Stuck ◽  
André Moser
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Cancer Survivors ◽  
Predictive Model ◽  
Breast Cancer Survivors ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Abstract P1-09-24: Oral health-related quality of life in women with early stage breast cancer

2015 ◽  
Author(s):  
Linda S Taichman ◽  
William G Giannobile ◽  
Thomas M Braun ◽  
Marita R Inglehart ◽  
Catherine H Van Poznak
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Oral Health ◽  
Early Stage ◽  
Early Stage Breast Cancer ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

scholarly journals The Relationship Between Health-Related Quality of Life and Saliva C-Reactive Protein and Diurnal Cortisol Rhythm in Latina Breast Cancer Survivors and Their Informal Caregivers: A Pilot Study

2020 ◽  
pp. 104365962092653
Author(s):  
Thaddeus W. W. Pace ◽  
Terry A. Badger ◽  
Chris Segrin ◽  
Alla Sikorskii ◽  
Tracy E. Crane
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Cancer Survivors ◽  
Breast Cancer Survivors ◽  
Health Related Quality ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Related Quality ◽  
Health Related

Introduction: To date, no study has explored associations between objective stress-related biomarkers (i.e., inflammatory markers, diurnal rhythm of cortisol) and health-related quality of life (HRQOL) in Latina breast cancer survivors and their informal caregivers (i.e., family, friends). Method: This cross-sectional feasibility study assessed saliva C-reactive protein, saliva diurnal cortisol rhythm (cortisol slope), and self-reported HRQOL (psychological, physical, and social domains) in 22 Latina survivor–caregiver dyads. Feasibility was defined as ≥85% samples collected over 2 days (on waking, in afternoon, and in evening). Associations between biomarkers and HRQOL were examined with correlational analyses. Results: Collection of saliva was feasible. Strongest associations were observed between survivor evening cortisol (as well as cortisol slope) and fatigue, a component of physical HRQOL. Discussion: Associations presented may help promote investigations of mechanisms linking stress-related biomarkers and HRQOL in Latina breast cancer survivor–caregiver dyads, which will facilitate development of culturally congruent interventions for this underserved group.

scholarly journals Adherence to Guidelines for Cancer Survivors and Health-Related Quality of Life among Korean Breast Cancer Survivors

Nutrients ◽  
2015 ◽  
Vol 7 (12) ◽  
pp. 10307-10319 ◽  
Author(s):  
Sihan Song ◽  
Eunkyung Hwang ◽  
Hyeong-Gon Moon ◽  
Dong-Young Noh ◽  
Jung Lee
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Cancer Survivors ◽  
Breast Cancer Survivors ◽  
Health Related Quality ◽  
Adherence To Guidelines ◽  
Related Quality ◽  
Health Related
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