Vascular endothelial growth factor receptor 1 signaling facilitates gastric ulcer healing and angiogenesis through the upregulation of epidermal growth factor expression on VEGFR1+CXCR4+ cells recruited from bone marrow

2013 ◽  
Vol 49 (3) ◽  
pp. 455-469 ◽  
Author(s):  
Takehito Sato ◽  
Hideki Amano ◽  
Yoshiya Ito ◽  
Koji Eshima ◽  
Tsutomu Minamino ◽  
...  
2006 ◽  
Vol 168 (1) ◽  
pp. 123-130 ◽  
Author(s):  
Wolfgang Füreder ◽  
Maria-Theresa Krauth ◽  
Wolfgang R. Sperr ◽  
Karoline Sonneck ◽  
Ingrid Simonitsch-Klupp ◽  
...  

2012 ◽  
Vol 03 (02) ◽  
pp. 93-92
Author(s):  
Alexander Kretzschmar

Vandetanib ist ein oraler Hemmer des RET-Kinase-, VEGF (Vascular Endothelial Growth Factor Receptor)- und EGFR (Epidermal Growth Factor Receptor)-Signalwegs. In einer zulassungsrelevanten, randomisierten, doppelblinden, placebokontrollierten Phase- III-Studie verlängerte der Tyrosinkinasehemmer das progressionsfreie Überleben (PFS) signifikant länger als Placebo.


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