Iatrogenic implantation of giant cell tumor at bone graft donor site and clinical recommendations to prevent “A Rare Avoidable Complication”

2012 ◽  
Vol 23 (6) ◽  
pp. 715-718 ◽  
Author(s):  
Ashish Gulia ◽  
Ajay Puri ◽  
Abhijeet Salunke ◽  
Subhash Desai ◽  
N. A. Jambhekar
2018 ◽  
Vol 32 (1) ◽  
pp. 249-253
Author(s):  
Khodamorad Jamshidi ◽  
Mehrdad Bahrabadi ◽  
Abolfazl Bagherifard ◽  
Mehdi Mohamadpour

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Biao Xu ◽  
Rui Ma ◽  
Wen-sheng Zhang ◽  
Qiang Zhang ◽  
Chang-song Zhao ◽  
...  

Abstract Background To evaluate the effect of reconstruction and repair, using a mini-plate and bone graft for HIV -positive patients with giant cell tumor of long bone. Methods We conducted a retrospective analysis of 12 HIV positive patients with giant cell tumor of long bone. A non-HIV-positive cohort of patients, matched for age, sex, and disease type, was selected as the control group. From June 2012 to August 2020, curettage by ultrasonic scalpel was performed in all patients, combined with min- plate and bone graft treatment. All patients were followed- up for 18 to 60 months. Limb function was evaluated, using the MSTS93 scoring system, and any examples of postoperative recurrence, distant metastasis, complications, MSTS93 score, and fracture prognosis were recorded. Results The mean age of HIV group was 43.5 years. The ratio of men to women was 11: 1. In all cases the histopathological diagnosis was clear, except the patients with primary malignant giant cell tumor of bone, including five, three, two, and two cases in the proximal tibia, distal femur, distal tibia, and talus, respectively. Following their surgery, all patients were followed up with an average of 31.24 ± 11.84 months. No local recurrence or pulmonary metastases were observed. Post-surgery, all the 12 patients showed good bone morphologic repair and reconstruction, good bone healing, good joint function, and no pathological fractures around their lesion. In the HIV group, one case of giant cell tumor in the proximal tibia showed mild articular surface collapse and mild valgus deformity of the knee joint but retained good joint function. The MSTS scores of excellent or good in the two groups comprised 83.3%, thus, there was no significant difference between them (P > 0.05). Compared with preoperatively, the MSTS scores in the HIV group were significantly improved, ranging from 7 to 11 points preoperatively to 24 to 27 points postoperatively; this difference was statistically significant (P < 0.05). Conclusion Reconstruction and repair, using a mini-plate and bone graft for HIV -positive patients with giant cell tumor of long bone can achieve satisfactory results. The mini- plate requires little space and is flexible during reconstruction and fixation, significantly reducing complications such as surgical site infection, as well as preserving joint function and avoiding amputation; therefore, it is a safe and effective treatment method.


2009 ◽  
Vol 5 (2) ◽  
pp. 123-128 ◽  
Author(s):  
Mohamed Abdelrahman ◽  
Ayman Abdelaziz Bassiony ◽  
Hisham Shalaby ◽  
Mohamed Kamal Assal

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Thipachart Punyaratabandhu ◽  
Boonrat Lohwongwatana ◽  
Chedtha Puncreobutr ◽  
Arkaphat Kosiyatrakul ◽  
Puwadon Veerapan ◽  
...  

Giant cell tumor of the bones occurring in the first metacarpals frequently requires entire metacarpal resection due to the aggressive nature and high rate of recurrence. Bone reconstruction can be performed with autogenous bone grafts. Here we describe a new technique of reconstruction using a patient-matched three-dimensional printed titanium first metacarpal prosthesis. This prosthesis has a special design for ligament reconstruction in the proximal and distal portions. Good hand function and aesthetic appearance were maintained at a 24-month follow-up visit. This reconstructive technique can avoid donor-site complications and spare the autogenous bone grafts for revision options.


2019 ◽  
Vol 3 (1) ◽  
pp. 6
Author(s):  
Yuliaji Narendra Putra ◽  
Rahadyan Magetsari

Latar belakang: giant cell tumor adalah suatu tumor jinak tulang yang meskipun jarang menyebabkan kematian, tetapi berpotensi untuk menjadi agresif dan mempunyai kemampuan untuk bermetastasis. Kasus: seorang perempuan berusia 20 tahun datang ke rumah sakit dengan keluhan terdapat benjolan di pergelangan tangan sebelah kiri yang telah berlangsung selama 6 bulan. Benjolan tersebut semakin lama dirasakan semakin membesar dan nyeri namun tidak mengganggu pergerakan dari pergelangan tangan. Pada pemeriksaan fisik ditemukan massa solid berukuran 5x3x2 cm dengan kesan terfiksir tulang tanpa tanda peradangan. Range of motion sendi pergelangan tangan masih dalam batas normal. Pada pemeriksaan radiologi ditemukan ekspansil, osteolitik ekstraosseus, serta lesi radiolusen tanpa batas sklerotik, dan reaksi periosteal pada akhir distal radius. Pasien ini didiagnosis dengan giant cell tumor radius distal kiri, kemudian dilakukan penanganan berupa eksisi tumor dan rekonstruksi dengan auto bone graft dari fibula. Evaluasi rutin selama 5 tahun menunjukkan hasil yang baik yang mana tidak tampak tanda-tanda rekurensi, tidak ada reaksi penolakan graft, dan range of motion sendi pergelangan tangan tetap dalam batas normal. Simpulan: tatalaksana giant cell tumor dengan eksisi dan rekonstruksi menggunakan auto bone graft menunjukkan hasil yang baik dan memuaskan.


2019 ◽  
Vol 9 (2) ◽  
pp. e0299-e0299
Author(s):  
Ting-Chien Tsai ◽  
Chien-Chin Chen ◽  
Hui-Kuang Huang ◽  
Jung-Pan Wang

2013 ◽  
Vol 47 (1) ◽  
pp. 107 ◽  
Author(s):  
ZileS Kundu ◽  
Vinay Gupta ◽  
Shobit Goel ◽  
SukhbirS Sangwan ◽  
Parveen Rana

2022 ◽  
Vol 4 (1) ◽  
pp. 1-3
Author(s):  
Pravakar Tripathy ◽  
Mahesh Chand Bansal ◽  
Rahul Upadhyay

Introduction: Giant cell tumor (GCT) is a distinctive lesion characterized by the proliferation of multinucleate giant cells in a stroma of mononuclear cells; it is generally seen in skeletally mature individuals. GCT is usually found in the long bones around the knee or in the distal radius but distal end of tibia, proximal humerus, vertebrae of young adults are unusual location. We report a case of GCT of the  distal end of tibia, with a secondary aneurysmal bone cyst, in a 26-year-old female. Based on our review of the medical literature, it appears that the occurrence of a GCT along with a secondary aneurysmal bone cyst (ABC) in distal end of tibia  is  less typical with challenging task for full tumor resection and restoration of ankle function to normal. Case Summary: 26 year old female presented with pain&swelling over left ankle since last six month. Biopsy was suggestive of GCT with ABC of lower third tibia. We managed this case with intralesional curettage using phenol and burr and bone graft harvested from left iliac crest for reconstruction of defect along with kwire fixation to achieve optimum anatomical restoration. Conclusion:  In cases of GCT, the management depends upon the various factors such as site, age, involvement of the bone, extent of bone involvement and whether there is articular involvement or not. Here Intra-articular GCT is managed with extended intralesional curettage with phenol. Bone graft plays a role of  agent for reconstruction of the defect and kwire for anatomical reduction.


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