Solitary fibrous tumor of the central nervous system: a clinicopathologic study of 24 cases

2011 ◽  
Vol 154 (2) ◽  
pp. 237-248 ◽  
Author(s):  
Hong Chen ◽  
Xian-Wei Zeng ◽  
Jin-Song Wu ◽  
Ya-Fang Dou ◽  
Yin Wang ◽  
...  
2018 ◽  
Vol 138 (1) ◽  
pp. 173-182 ◽  
Author(s):  
Connor J. Kinslow ◽  
Samuel S. Bruce ◽  
Ali I. Rae ◽  
Sameer A. Sheth ◽  
Guy M. McKhann ◽  
...  

2021 ◽  
Vol 13 (1) ◽  
pp. 259-266
Author(s):  
Ye-Tao Zhu ◽  
Yang Liu ◽  
Li-Gang Chen ◽  
Da-Ping Song

Solitary fibrous tumor is a very rare mesenchymal tumor that occurs mostly in the pleura, and there are few reported cases of a presence in the central nervous system, particularly in the cerebellum. In 2016, the WHO classified solitary fibrous tumors into grade I. In this article, we present a case of malignant solitary fibrous tumor recurring 8 years after surgery in a 63-year-old male. Magnetic resonance imaging showed low to intermediate mixed signal intensity on T1W1. Immunohistochemical staining positivity for Vimentin, CD99, CD34 and Bcl-2, it is consistent with the immunohistochemical characteristics of solitary fibrous tumor. We resected the patient’s tumor, and the patient was followed up for 3 months with no signs of recurrence. Solitary fibrous tumors are very rare in the central nervous system. Immunohistochemical staining positivity for CD34 and Bcl-2 is strongly expressed in most solitary fibrous tumor. Surgical resection is the preferred treatment. Due to the small number of cases, the biological behavior and prognosis of this tumor need to be further explored.


2019 ◽  
Vol 143 (3) ◽  
pp. 457-464 ◽  
Author(s):  
Deborah Boyett ◽  
Connor J. Kinslow ◽  
Samuel S. Bruce ◽  
Adam M. Sonabend ◽  
Ali I. Rae ◽  
...  

2019 ◽  
Vol 39 (2) ◽  
pp. 141-146
Author(s):  
Lijuan Cao ◽  
Xialing Zhang ◽  
Yin Wang ◽  
Yun Bao ◽  
Feng Tang

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Amer Sebaaly ◽  
Lara Raffoul ◽  
Ronald Moussa

Solitary fibrous tumor (SFT) is a rare neoplasm occurring in the central nervous system. It rarely occurs in the spine. This paper reports the fifth case of SFT in a 34-year-old female and focusses on differential diagnosis and importance of surgical treatment.


2000 ◽  
Vol 92 (2) ◽  
pp. 217-220 ◽  
Author(s):  
Sarel J. Vorster ◽  
Richard A. Prayson ◽  
Joung H. Lee

✓ Solitary fibrous tumor (SFT) is a neoplasm first described as a tumor of mesenchymal origin involving soft tissues. The authors provide a review of the literature with detailed pathological analysis and radiological description of SFTs involving the central nervous system. The authors report a rare case of a SFT of the thoracic spine in an adult man presenting with myelopathy. Magnetic resonance imaging revealed a well-circumscribed, intradural, extramedullary mass at the T2–3 level. Histological examination demonstrated a proliferation of predominantly spindle-shaped cells with a collagen-matrix background. Immunohistochemical staining was positive for vimentin and CD34 and negative for S-100 and epithelial membrane antigen with an MIB-1 labeling index of 2.6%. Review of the literature revealed 10 cases in which this tumor, frequently found in the pleura, was involved in the central nervous system. Although rare and their clinical significance as yet unknown, SFTs may be considered in the differential diagnosis of intradural spinal cord lesions. The natural history is also unknown, but these tumors appear to be biologically benign.


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