scholarly journals Malignant Solitary Fibrous Tumor of the Right Cerebellum: A Case Report

2021 ◽  
Vol 13 (1) ◽  
pp. 259-266
Author(s):  
Ye-Tao Zhu ◽  
Yang Liu ◽  
Li-Gang Chen ◽  
Da-Ping Song
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Solitary Fibrous Tumor ◽  
Immunohistochemical Staining ◽  
Biological Behavior ◽  
Resonance Imaging ◽  
Solitary Fibrous Tumors ◽  
The Central Nervous System ◽  
Fibrous Tumor ◽  
The Right

Solitary fibrous tumor is a very rare mesenchymal tumor that occurs mostly in the pleura, and there are few reported cases of a presence in the central nervous system, particularly in the cerebellum. In 2016, the WHO classified solitary fibrous tumors into grade I. In this article, we present a case of malignant solitary fibrous tumor recurring 8 years after surgery in a 63-year-old male. Magnetic resonance imaging showed low to intermediate mixed signal intensity on T1W1. Immunohistochemical staining positivity for Vimentin, CD99, CD34 and Bcl-2, it is consistent with the immunohistochemical characteristics of solitary fibrous tumor. We resected the patient’s tumor, and the patient was followed up for 3 months with no signs of recurrence. Solitary fibrous tumors are very rare in the central nervous system. Immunohistochemical staining positivity for CD34 and Bcl-2 is strongly expressed in most solitary fibrous tumor. Surgical resection is the preferred treatment. Due to the small number of cases, the biological behavior and prognosis of this tumor need to be further explored.

Solitary fibrous tumor of the central nervous system: a clinicopathologic study of 24 cases

2011 ◽  
Vol 154 (2) ◽  
pp. 237-248 ◽  
Author(s):  
Hong Chen ◽  
Xian-Wei Zeng ◽  
Jin-Song Wu ◽  
Ya-Fang Dou ◽  
Yin Wang ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Solitary Fibrous Tumor ◽  
Clinicopathologic Study ◽  
System A ◽  
The Central Nervous System ◽  
Fibrous Tumor

Solitary Fibrous Tumors in the Central Nervous System

2003 ◽  
Vol 127 (4) ◽  
pp. 432-439 ◽  
Author(s):  
Tarik Tihan ◽  
Michael Viglione ◽  
Marc K. Rosenblum ◽  
Alessandro Olivi ◽  
Peter C. Burger
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Biological Behavior ◽  
Clinicopathologic Features ◽  
Distinct Entity ◽  
Total Resection ◽  
Solitary Fibrous Tumors ◽  
The Central Nervous System ◽  
Extracranial Metastases

Abstract Context.—Solitary fibrous tumors (SFTs) of the central nervous system are rare neoplasms that usually present as dura-based masses and clinically resemble meningiomas. Histologically, they can be similar to fibrous meningioma or hemangiopericytoma (HPC). In particular, densely cellular regions seen in some SFTs can be indistinguishable from HPC. Little is known about the biological behavior of SFTs, although most seem amenable to total resection. Objectives.—To define the clinicopathologic spectrum of SFTs in the central nervous system and to outline their differences from HPC and meningioma. Design.—We present the clinicopathologic features of 18 patients with SFT and compare them with those of an age- and sex-matched cohort of HPCs. Results.—Eleven SFTs were supratentorial, 3 were infratentorial, and 4 were intraspinal. Four of the 18 tumors were intra-axial (2 in the lateral ventricles and 2 within the spinal cord). Histologically, SFTs were similar to their soft tissue counterparts. Six tumors (6/18) had densely cellular regions, and 1 tumor showed frankly anaplastic features. All but 3 patients underwent gross total resection, and there were no metastases or tumor-related mortalities during the median follow-up of 40 months. In contrast, there were 15 local recurrences (83%), 5 extracranial metastases (27%), and 4 tumor-related deaths (22%) in the HPC cohort. Conclusions.—Our study presents the clinicopathologic features of SFT as a distinct entity from both meningioma and HPC. We also present unusual examples of anaplastic, intraventricular, and intramedullary spinal SFTs that expand the clinicopathologic spectrum of these uncommon and sometimes diagnostically difficult neoplasms.

scholarly journals Spinal location is prognostic of survival for solitary-fibrous tumor/hemangiopericytoma of the central nervous system

2019 ◽  
Vol 143 (3) ◽  
pp. 457-464 ◽  
Author(s):  
Deborah Boyett ◽  
Connor J. Kinslow ◽  
Samuel S. Bruce ◽  
Adam M. Sonabend ◽  
Ali I. Rae ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Solitary Fibrous Tumor ◽  
The Central Nervous System ◽  
Fibrous Tumor

A case of solitary fibrous tumor/hemangiopericytoma in the central nervous system with papillary morphology

2019 ◽  
Vol 39 (2) ◽  
pp. 141-146
Author(s):  
Lijuan Cao ◽  
Xialing Zhang ◽  
Yin Wang ◽  
Yun Bao ◽  
Feng Tang
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Solitary Fibrous Tumor ◽  
The Central Nervous System ◽  
Fibrous Tumor

scholarly journals Solitary Fibrous Tumor of the Lumbar Spine: The Great Mimicker—Report of the Fifth Case

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Amer Sebaaly ◽  
Lara Raffoul ◽  
Ronald Moussa
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Differential Diagnosis ◽  
Surgical Treatment ◽  
Lumbar Spine ◽  
Solitary Fibrous Tumor ◽  
Rare Neoplasm ◽  
The Central Nervous System ◽  
Fibrous Tumor

Solitary fibrous tumor (SFT) is a rare neoplasm occurring in the central nervous system. It rarely occurs in the spine. This paper reports the fifth case of SFT in a 34-year-old female and focusses on differential diagnosis and importance of surgical treatment.

Solitary-fibrous tumor/hemangiopericytoma of the central nervous system: a population-based study

2018 ◽  
Vol 138 (1) ◽  
pp. 173-182 ◽  
Author(s):  
Connor J. Kinslow ◽  
Samuel S. Bruce ◽  
Ali I. Rae ◽  
Sameer A. Sheth ◽  
Guy M. McKhann ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Solitary Fibrous Tumor ◽  
Population Based ◽  
Population Based Study ◽  
System A ◽  
The Central Nervous System ◽  
Fibrous Tumor

Solitary fibrous tumor of the thoracic spine. Case report and review of the literature

2000 ◽  
Vol 92 (2) ◽  
pp. 217-220 ◽  
Author(s):  
Sarel J. Vorster ◽  
Richard A. Prayson ◽  
Joung H. Lee
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Thoracic Spine ◽  
Solitary Fibrous Tumor ◽  
Soft Tissues ◽  
Review Of The Literature ◽  
Content Type ◽  
The Central Nervous System ◽  
Fibrous Tumor ◽  
Fine Print

✓ Solitary fibrous tumor (SFT) is a neoplasm first described as a tumor of mesenchymal origin involving soft tissues. The authors provide a review of the literature with detailed pathological analysis and radiological description of SFTs involving the central nervous system. The authors report a rare case of a SFT of the thoracic spine in an adult man presenting with myelopathy. Magnetic resonance imaging revealed a well-circumscribed, intradural, extramedullary mass at the T2–3 level. Histological examination demonstrated a proliferation of predominantly spindle-shaped cells with a collagen-matrix background. Immunohistochemical staining was positive for vimentin and CD34 and negative for S-100 and epithelial membrane antigen with an MIB-1 labeling index of 2.6%. Review of the literature revealed 10 cases in which this tumor, frequently found in the pleura, was involved in the central nervous system. Although rare and their clinical significance as yet unknown, SFTs may be considered in the differential diagnosis of intradural spinal cord lesions. The natural history is also unknown, but these tumors appear to be biologically benign.

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