Defining the timing and role of acute postoperative imaging in pituitary adenoma surgery: clinical study

2020 ◽  
Vol 162 (10) ◽  
pp. 2353-2360
Author(s):  
Katherine E. Kunigelis ◽  
Gregory Arnone ◽  
Gregoire Chatain ◽  
Jessa Hoffman ◽  
Oscar Chatain ◽  
...  
Keyword(s):  
Clinical Study ◽  
Pituitary Adenoma ◽  
Postoperative Imaging

PTTG has a Dual Role of Promotion-Inhibition in the Development of Pituitary Adenomas

2019 ◽  
Vol 26 (11) ◽  
pp. 800-818
Author(s):  
Zujian Xiong ◽  
Xuejun Li ◽  
Qi Yang
Keyword(s):  
Cell Cycle ◽  
Pituitary Adenoma ◽  
Pituitary Adenomas ◽  
Cell Cycle Progression ◽  
Key Factors ◽  
Cycle Progression ◽  
Sister Chromatids ◽  
Regulation Of Cell Cycle ◽  
Late Stages

Pituitary Tumor Transforming Gene (PTTG) of human is known as a checkpoint gene in the middle and late stages of mitosis, and is also a proto-oncogene that promotes cell cycle progression. In the nucleus, PTTG works as securin in controlling the mid-term segregation of sister chromatids. Overexpression of PTTG, entering the nucleus with the help of PBF in pituitary adenomas, participates in the regulation of cell cycle, interferes with DNA repair, induces genetic instability, transactivates FGF-2 and VEGF and promotes angiogenesis and tumor invasion. Simultaneously, overexpression of PTTG induces tumor cell senescence through the DNA damage pathway, making pituitary adenoma possessing the potential self-limiting ability. To elucidate the mechanism of PTTG in the regulation of pituitary adenomas, we focus on both the positive and negative function of PTTG and find out key factors interacted with PTTG in pituitary adenomas. Furthermore, we discuss other possible mechanisms correlate with PTTG in pituitary adenoma initiation and development and the potential value of PTTG in clinical treatment.

An approach to the clinical manifestation of Rupavriddhi Rupahani Rupantara in Avarana

2018 ◽  
Vol 3 (4) ◽  
Author(s):  
Dr. Sharanamma . ◽  
Dr. A. S. Prashanth ◽  
Dr. S. G. Chavan
Keyword(s):  
Clinical Practice ◽  
Clinical Study ◽  
Present Article ◽  
Clinical Manifestation ◽  
Basic Concept ◽  
Favorable Condition ◽  
Wrong Diagnosis

Ayurveda believes in different pathology which sets in different Srotas to produce different diseases. Whenever a favorable condition and situation arise, diseases will manifest. Nanatmaja Vikara, Anubandha, Gatavata and Avarana are different pathologies explained in Ayurveda. Avarana is one of the most difficult concept to understand teach and incorporate in clinical practice. It is either least observed, diagnosed or goes unidentified due to lack of skill. To understand and analyze the Avarana, Meticulous knowledge of basic concept of Ayurveda is essential. It is assumed that symptoms complex in Avarana leads to misunderstanding, wrong diagnosis and sometimes end with complications. The symptoms produced in Avarana are based on the principles of Rupahani (Karmakshaya), Rupavriddi (Karmavriddhi) and Rupantara (Anya Karma). The present article is an attempt made to have a critical clinical study of role of Avarana in the manifestation of Rupavriddhi, Rupahani, Rupantara.

scholarly journals Role of matrix Metalloproteinases in pituitary adenoma invasion

2018 ◽  
Vol 4 (1) ◽  
Author(s):  
Chengxian Yang ◽  
Xinjie Bao ◽  
Renzhi Wang
Keyword(s):  
Pituitary Adenoma ◽  
Matrix Metalloproteinases

A Clinical Study to Evaluate the Role of Vitamin D3 in Allergic Rhinitis

2022 ◽  
Author(s):  
Gopika Kalsotra ◽  
Aditiya Saraf ◽  
Apurva Raina ◽  
Parmod Kalsotra ◽  
Rupali Sharma ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Clinical Study ◽  
Vitamin D3

Role of patala kshara and gokshuradi choorna in renal calculi – a clinical study

2021 ◽  
Vol 15 (4) ◽  
pp. 255
Author(s):  
Rabinarayan Tripathy ◽  
ShanuK Babu ◽  
PN Rajeshwari ◽  
Shaithya Raj ◽  
SusmitaPriyadarshinee Otta
Keyword(s):  
Clinical Study ◽  
Renal Calculi

The Role of Arthroscopy in the Treatment of Common Wrist Disorders: A Retrospective Clinical Study

2021 ◽  
Vol 28 (6) ◽  
pp. 1
Author(s):  
Muhammed Köroğlu ◽  
Kadir Ertem ◽  
Okan Aslantürk
Keyword(s):  
Clinical Study ◽  
Retrospective Clinical Study
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