Effect of spirulina maxima on the haloperidol induced tardive dyskinesia and oxidative stress in rats

2007 ◽  
Vol 114 (9) ◽  
pp. 1217-1225 ◽  
Author(s):  
S. R. Thaakur ◽  
B. Jyothi
Keyword(s):  
Oxidative Stress ◽  
Tardive Dyskinesia ◽  
Spirulina Maxima ◽  
And Oxidative Stress

Markers of Glutamatergic Neurotransmission and Oxidative Stress Associated With Tardive Dyskinesia

1998 ◽  
Vol 155 (9) ◽  
pp. 1207-1213 ◽  
Author(s):  
Guochuan Tsai ◽  
Donald C. Goff ◽  
Robert W. Chang ◽  
James Flood ◽  
Lee Baer ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Tardive Dyskinesia ◽  
Glutamatergic Neurotransmission ◽  
And Oxidative Stress

scholarly journals Spirulina Maxima Decreases Endothelial Damage and Oxidative Stress Indicators in Patients with Systemic Arterial Hypertension: Results from Exploratory Controlled Clinical Trial

2018 ◽  
Author(s):  
Jesús Martínez-Sámano ◽  
Adriana Torres-Montes de Oca ◽  
Oscar Ivan Luqueño-Bocardo ◽  
Patricia V. Torres-Durán ◽  
Marco Antonio Juárez-Oropeza
Keyword(s):  
Oxidative Stress ◽  
Glutathione Peroxidase ◽  
Arterial Hypertension ◽  
Endothelial Damage ◽  
Oxidized Glutathione ◽  
Spirulina Maxima ◽  
Stress Indicators ◽  
Systemic Arterial Hypertension ◽  
Oxidative Stress Indicators ◽  
And Oxidative Stress

1) Background: Spirulina (Arthrospira) maxima has shown beneficial effects such anti-dyslipidemic, antiviral, antioxidant and antihypertensive. However, there are few and limited clinical studies. 2) Methods: a prospective, randomized, parallel pilot study of 4.5 g administration of Spirulina maxima or placebo for 12 weeks in 16 patients with systemic arterial hypertension undergoing treatment with ACE inhibitors was performed to assess the effects on endothelial damage and oxidative stress indicators. The blood levels of sICAM-1, sVCAM-1, endothelin-1, and sE-selectin were quantified; the activities of catalase, superoxide dismutase, glutathione peroxidase, glutathione reductase and concentrations of reduced glutathione, oxidized glutathione, and thiobarbituric acid reactive susbtances, were also quantified before and after the treatment period. 3) Results: There were statistically significant (p < 0.05) decreases in systolic blood pressure, sVCAM-1, sE-selectin and endothelin-1 levels, and increases in glutathione peroxidase activity and oxidized glutathione levels. 4) Conclusion: The effects found in the present study agree with antihypertensive and antioxidant effects previously reported for Spirulina maxima. However, this is the first report about the effects on indicators of endothelial damage. More research in this field is necessary to gain an insight into the effects of Spirulina on these indicators.   

scholarly journals Estrogen Receptor Activation and Tardive Dyskinesia

2000 ◽  
Vol 45 (3) ◽  
pp. 288-290 ◽  
Author(s):  
Peter Turrone ◽  
Mary V Seeman ◽  
Simone Silvestri
Keyword(s):  
Oxidative Stress ◽  
Tardive Dyskinesia ◽  
Estrogen Replacement Therapy ◽  
Cell Damage ◽  
Receptor Activation ◽  
Estrogen Replacement ◽  
Potential Influence ◽  
The Central Nervous System ◽  
And Oxidative Stress

Objective: To undertake a selective review of the epidemiology, etiology, and treatment of tardive dyskinesia (TD), with emphasis on the potential influence of estrogen in its expression. Method: Both Medline and Psycinfo databases were used to search for articles with the following key words: tardive dyskinesia, humans, animals, dopamine, estrogen, estrogen replacement therapy, antioxidants and oxidative stress. Results: The studies reviewed here suggest that estrogen modulates dopamine-mediated behaviours and that it protects against oxidative stress-induced cell damage caused by long-term exposure to antipsychotic medication. Conclusions: Estrogen's multimodal role in the central nervous system may prove useful for the amelioration or prevention of TD. All the evidence suggests that a placebo-controlled, randomized trial with safer forms of estrogen should be conducted in postmenopausal women with TD.

scholarly journals Protective effects of Spirulina maxima on hyperlipidemia and oxidative-stress induced by lead acetate in the liver and kidney

2010 ◽  
Vol 9 (1) ◽  
pp. 35 ◽  
Author(s):  
Johny C Ponce-Canchihuamán ◽  
Oscar Pérez-Méndez ◽  
Rolando Hernández-Muñoz ◽  
Patricia V Torres-Durán ◽  
Marco A Juárez-Oropeza
Keyword(s):  
Oxidative Stress ◽  
Lead Acetate ◽  
Protective Effects ◽  
Spirulina Maxima ◽  
Liver And Kidney ◽  
And Oxidative Stress

scholarly journals Spirulina maxima Decreases Endothelial Damage and Oxidative Stress Indicators in Patients with Systemic Arterial Hypertension: Results from Exploratory Controlled Clinical Trial

Marine Drugs ◽  
2018 ◽  
Vol 16 (12) ◽  
pp. 496 ◽  
Author(s):  
Jesús Martínez-Sámano ◽  
Adriana Torres-Montes de Oca ◽  
Oscar Luqueño-Bocardo ◽  
Patricia Torres-Durán ◽  
Marco Juárez-Oropeza
Keyword(s):  
Oxidative Stress ◽  
Glutathione Peroxidase ◽  
Arterial Hypertension ◽  
Endothelial Damage ◽  
Oxidized Glutathione ◽  
Spirulina Maxima ◽  
Stress Indicators ◽  
Systemic Arterial Hypertension ◽  
Oxidative Stress Indicators ◽  
And Oxidative Stress

(1) Background: Spirulina (Arthrospira) maxima has shown beneficial effects such as being anti-dyslipidemic, antiviral, antioxidant and antihypertensive. However, there are few and limited clinical studies. (2) Methods: a prospective, randomized, parallel pilot study of 4.5 g administration of Spirulina maxima or placebo for 12 weeks in 16 patients with systemic arterial hypertension (SAH) undergoing treatment with angiotensin-converting enzyme (ACE) inhibitors was performed to assess the effects on endothelial damage and oxidative stress indicators. The blood levels of sICAM-1, sVCAM-1, endothelin-1, and sE-selectin were quantified; the activities of catalase, superoxide dismutase, glutathione peroxidase, glutathione reductase and concentrations of reduced glutathione, oxidized glutathione, and thiobarbituric acid reactive substances, were also quantified before and after the treatment period. (3) Results: There were statistically significant (p < 0.05) decreases in systolic blood pressure, sVCAM-1, sE-selectin and endothelin-1 levels, and increases in glutathione peroxidase activity and oxidized glutathione levels. (4) Conclusion: The effects found in the present study agree with antihypertensive and antioxidant effects previously reported for Spirulina maxima. However, this is the first report about the effects on indicators of endothelial damage. More research in this field is necessary to gain an insight into the effects of Spirulina on these indicators.

Association between calcitriol and paricalcitol with oxidative stress in patients with hemodialysis

2020 ◽  
pp. 1-8
Author(s):  
Hasan Haci Yeter ◽  
Berfu Korucu ◽  
Elif Burcu Bali ◽  
Ulver Derici
Keyword(s):  
Oxidative Stress ◽  
Vitamin D ◽  
Antioxidant Status ◽  
Total Antioxidant Status ◽  
Stress Index ◽  
Total Oxidant Status ◽  
Vitamin D Analog ◽  
Total Antioxidant ◽  
Oxidant Status ◽  
And Oxidative Stress

Abstract. Background: The pathophysiological basis of chronic kidney disease and its complications, including cardiovascular disease, are associated with chronic inflammation and oxidative stress. We investigated the effects of active vitamin D (calcitriol) and synthetic vitamin D analog (paricalcitol) on oxidative stress in hemodialysis patients. Methods: This cross-sectional study was composed of 83 patients with a minimum hemodialysis vintage of one year. Patients with a history of any infection, malignancy, and chronic inflammatory disease were excluded. Oxidative markers (total oxidant and antioxidant status) and inflammation markers (C-reactive protein and interleukin-6) were analyzed. Results: A total of 47% (39/83) patients were using active or analog vitamin D. Total antioxidant status was significantly higher in patients with using active or analog vitamin D than those who did not use (p = 0.006). Whereas, total oxidant status and oxidative stress index were significantly higher in patients with not using vitamin D when compared with the patients who were using vitamin D preparation (p = 0.005 and p = 0.004, respectively). On the other hand, total antioxidant status, total oxidant status, and oxidative stress index were similar between patients who used active vitamin D or vitamin D analog (p = 0.6; p = 0.4 and p = 0.7, respectively). Conclusion: The use of active or selective vitamin D analog in these patients decreases total oxidant status and increases total antioxidant status. Also, paricalcitol is as effective as calcitriol in decreasing total oxidant status and increasing total antioxidant status in patients with chronic kidney disease.

Sign in / Sign up

Export Citation Format

Share Document