Synthesis and Antiinflammatoryand Anticancer Activity Evaluation of Some Condensed Pyrimidines

2000 ◽  
Vol 131 (5) ◽  
pp. 0501-0509 ◽  
Author(s):  
Sham M. Sondhi ◽  
Nidhi Singhal ◽  
Rajeshwar P. Verma ◽  
Sudershan K. Arora ◽  
Rakesh Shukla ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Activity Evaluation

Synthesis, anti-inflammatory and anticancer activity evaluation of some novel acridine derivatives

2010 ◽  
Vol 45 (2) ◽  
pp. 555-563 ◽  
Author(s):  
Sham M. Sondhi ◽  
Jaiveer Singh ◽  
Reshma Rani ◽  
P.P. Gupta ◽  
S.K. Agrawal ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Acridine Derivatives ◽  
Activity Evaluation ◽  
Anti Inflammatory

scholarly journals Synthesis and anticancer activity evaluation of naphthalene-substituted triazole spirodienones

2020 ◽  
pp. 113039
Author(s):  
Lan Luo ◽  
Jing Jing Jia ◽  
Qiu Zhong ◽  
Xue Zhong ◽  
Shilong Zheng ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Activity Evaluation

scholarly journals Modular Total Synthesis and Cell-Based Anticancer Activity Evaluation of Ouabagenin and Other Cardiotonic Steroids with Varying Degrees of Oxygenation

2019 ◽  
Vol 141 (12) ◽  
pp. 4849-4860 ◽  
Author(s):  
Hem Raj Khatri ◽  
Bijay Bhattarai ◽  
Will Kaplan ◽  
Zhongzheng Li ◽  
Marcus John Curtis Long ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Anticancer Activity ◽  
Activity Evaluation

Synthesis and anticancer activity evaluation of resveratrol–chalcone conjugates

MedChemComm ◽  
2014 ◽  
Vol 5 (4) ◽  
pp. 528 ◽  
Author(s):  
Deepak Kumar ◽  
K. Kranthi Raj ◽  
Sanjay V. Malhotra ◽  
Diwan S. Rawat
Keyword(s):  
Anticancer Activity ◽  
Activity Evaluation

Novel N-(aryl/heteroaryl)-2-chlorobenzenesulfonamide derivatives: Synthesis and anticancer activity evaluation

2020 ◽  
Vol 104 ◽  
pp. 104309
Author(s):  
Anita Bułakowska ◽  
Jarosław Sławiński ◽  
Kamila Siedlecka-Kroplewska ◽  
Grzegorz Stasiłojć ◽  
Marcin Serocki ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Activity Evaluation

scholarly journals Synthesis and Anticancer Activity Evaluation of Azepinobisindoles; the Isomeric Iheyamine A Derivatives

2019 ◽  
Vol 35 (2) ◽  
pp. 723-731
Author(s):  
Weerachai Phutdhawong ◽  
Sopita Rattanopas ◽  
Jitnapa Sirirak ◽  
Thongchai Taechowisan ◽  
Waya S. Phutdhawong
Keyword(s):  
Anticancer Activity ◽  
Cell Line ◽  
Cell Lines ◽  
Human Cancer ◽  
Docking Study ◽  
Inhibitory Effect ◽  
Molecular Docking Study ◽  
Human Cancer Cell Lines ◽  
Activity Evaluation ◽  
Cancer Line

Azepinobisindole derivatives, the isomeric Iheyamine skeleton, was prepared and its anticancer activity evaluation were investigated against two human cancer cell lines, Hepatocellular carcinoma (HepG2) and human cervical cancer line (Hela) as well as the normal cell line (Vero cell line) using MTT assay. The anticancer activity results indicated that 2-methoxy-5-methyl-5H-azepino[2,3-b:4,5-bʹ]diindole was the most active derivative against tested cell lines. Additionally, molecular docking study in silico the possible inhibitory effect of cyclin-dependent kinase 2 (CDK2) by the azepinoindole revealed that all synthesized compounds fit well in the binding cavity of CDK2.

Synthesis and anticancer activity evaluation of some acridine derivatives

2014 ◽  
Vol 24 (5) ◽  
pp. 1942-1951 ◽  
Author(s):  
Surbhi Arya ◽  
Anuj Kumar ◽  
Nikhil Kumar ◽  
Partha Roy ◽  
S. M. Sondhi
Keyword(s):  
Anticancer Activity ◽  
Acridine Derivatives ◽  
Activity Evaluation

Synthesis and anticancer activity evaluation of novel oxacalix[2]arene[2]pyrimidine derivatives

2019 ◽  
Vol 28 (4) ◽  
pp. 580-590 ◽  
Author(s):  
Tonghui Huang ◽  
Xin Wu ◽  
Tianya Liu ◽  
Lin An ◽  
Xiaoxing Yin
Keyword(s):  
Anticancer Activity ◽  
Pyrimidine Derivatives ◽  
Activity Evaluation
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