An electrochemical sensor based on SiO2@TiO2-embedded molecularly imprinted polymers for selective and sensitive determination of theophylline

2017 ◽  
Vol 21 (12) ◽  
pp. 3683-3691 ◽  
Author(s):  
Tian Gan ◽  
Aixia Zhao ◽  
Zhikai Wang ◽  
Pan Liu ◽  
Junyong Sun ◽  
...  
Keyword(s):  
Electrochemical Sensor ◽  
Molecularly Imprinted Polymers ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Sensitive Determination

scholarly journals CONSTRUCTION OF A NEW ELECTROCHEMICAL SENSOR BASED ON A NEW MOLECULARLY IMPRINTED POLYMERS(MIPS) FOR HIGHLY SELECTIVE AND SENSITIVE DETERMINATION OF CLEBOPRIDE (CBD) IN PHARMACEUTICAL COMMERCIAL SAMPLES

2021 ◽  
Vol 52 (2) ◽  
pp. 367-376
Author(s):  
Y. K. Al-Bayati
Keyword(s):  
Ethylene Glycol ◽  
Molecularly Imprinted Polymers ◽  
Solid Phase ◽  
Pharmaceutical Preparation ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Relative Standard ◽  
Sensitive Determination ◽  
Cross Linker

Clebopride (CBD) selective molecularly imprinted polymers(MIPs) were based on ion-pair by prepared four polymers(MIPs) using CBD as the template a well as (Acryl amide) (AAM), 2-Acrylamido-2-Methyl-1-Propane sulphonic Acid (2-AAMMPSA as monomer, used N,N-ethylenebismethacrylamide (EBMAA) ,ethylene glycol dimethacrylate ethylene glycol(EGDMAC), N, N-methylene bisacrylamide (NNMBAAM)) as cross linker and used benzoyl peroxide as initiator . NIPs prepared by using the same composition of MIPs except the template (CBD). The MIPs were prepared using variation  ratio of monomer and cross linker .These MIPs applicate as solid phase extraction for determination CBD in pharmaceutical preparation used UV as detector .the results gave good response, where the reconstruction percentage (Rec%) value of CBD drug took the range (99- 101% ), and the relative standard deviation (RSD%) value took the range (0.27% - 0.93 %) for standard solution and Rec% took values of (98- 99) %, and RSD% took values of (0.86 – 1.62) % of CBD drug for the Clebopride pharmaceutical.

scholarly journals Molecularly Imprinted Polymers-Coated CdTe Quantum Dots for Highly Sensitive and Selective Fluorescent Determination of Ferulic Acid

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Zhihong Wang ◽  
Ruiqing Long ◽  
Mijun Peng ◽  
Te Li ◽  
Shuyun Shi
Keyword(s):  
Quantum Dots ◽  
Ferulic Acid ◽  
Molecularly Imprinted Polymers ◽  
High Sensitivity ◽  
Complex Matrix ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Cdte Qds ◽  
Sensitive Determination

Ferulic acid (FA), an important phenolic acid, is widely distributed in higher plants and presents many pharmacological effects. Therefore, sensitive determination of FA in complex matrix is necessary. Molecularly imprinted polymers-coated CdTe quantum dots (CdTe-QDs@MIPs) exhibited incomparable advantages because of their combination of excellent selectivity of MIPs and high sensitivity of QDs. Here, a fluorescent probe based on CdTe-QDs@MIPs was successfully fabricated for selective and sensitive determination of FA. MIPs shell was obtained by the reverse microemulsion method using FA, 3-(aminopropyl) triethoxysilane (APTES), and tetraethyl orthosilicate (TEOS), as template, functional monomer, and crosslinker. In optimal conditions, the fluorescence CdTe-QDs@MIPs sensor exhibited fast response (within only 3 min), high sensitivity (limit of detection, LOD at 0.85 μg/l), excellent linear ranges (2–100 μg/l) with a correlation coefficient of 0.9996, and distinguished selectivity for FA. Satisfactory recoveries from 91.8% to 110.3% were achieved with precisions below 6.6% for FA analysis in real pineapple juice and apple juice by developed CdTe-QDs@MIPs. The fluorescence results coincided well with those obtained by high-performance liquid chromatography (HPLC). It could be concluded that the resultant CdTe-QDs@MIPs offered a new way for rapid and sensitive analysis of FA in the complex matrix.

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