Serum levels of homocysteine at admission are associated with post-stroke depression in acute ischemic stroke

2017 ◽  
Vol 38 (5) ◽  
pp. 811-817 ◽  
Author(s):  
Yan Li ◽  
Li-Li Cao ◽  
Lin Liu ◽  
Qin-De Qi
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Serum Levels ◽  
Post Stroke ◽  
Post Stroke Depression

scholarly journals Serum lipid profiles and post-stroke depression in acute ischemic stroke patients

2019 ◽  
Vol Volume 15 ◽  
pp. 1573-1583 ◽  
Author(s):  
Huiping Shen ◽  
Xinjie Tu ◽  
Xiaoqian Luan ◽  
Yaying Zeng ◽  
Jincai He ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Serum Lipid ◽  
Lipid Profiles ◽  
Stroke Patients ◽  
Post Stroke ◽  
Post Stroke Depression

scholarly journals Factors Affecting Post-Stroke Depression in Acute Ischemic Stroke Patients after 3 Months

2021 ◽  
Vol 11 (11) ◽  
pp. 1178
Author(s):  
Chan-Hyuk Lee ◽  
Su Hong Jeon ◽  
Min Ju Kim ◽  
Gyu Dam Ra ◽  
Yong-Hyun Lee ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Prognostic Factors ◽  
Environmental Factors ◽  
Acute Ischemic Stroke ◽  
Study Design ◽  
Rating Scale ◽  
Stroke Patients ◽  
Post Stroke ◽  
Hospitalization Period ◽  
Post Stroke Depression

Post-stroke depression (PSD) affects approximately one-third of stroke patients. PSD not only impairs recovery and lowers quality of life, but has also serious neurological consequences, high mortality, and stroke recurrence risks. Studies on PSD-related prognostic factors are still lacking, especially environmental factors. Moreover, relieving factors after PSD in stroke patients has not been reported. This study aimed to investigate (study design 1) risk factors for PSD diagnosis after three months, and (study design 2) related factors for the relieving of early PSD after three months. This retrospective study included 227 patients hospitalized for acute ischemic stroke within three days at Jeonbuk National University Hospital from January to December 2019. The depressive status was assessed using the Hamilton Depression Rating Scale (HDRS) at admission and after three months. Clinical and laboratory data were analyzed for relevant prognostic factors. (Study design 1) HDRS score at admission (adjusted odds ratio (aOR) 1.22, 95% confidence interval (CI) 1.14–1.31; p < 0.001) and hospitalization period (aOR 1.11, 95% CI 1.02–1.20; p = 0.013) were confirmed as prognostic factors of PSD after three months. (Study design 2) The National Institute of Health Stroke Scale (NIHSS) score at discharge (aOR 0.80, 95% CI 0.68–0.94; p = 0.006) and HDRS score at admission (aOR 0.80, 95% CI 0.71–0.89; p < 0.001) were confirmed as prognostic factors of depression improvement after three months. In conclusion, environmental factors such as hospitalization period could be important in managing PSD. Factors related to PSD improvement are expected to be helpful in establishing a strategy for PSD recovery.

scholarly journals Higher fasting C-peptide is associated with post-stroke depression: a multicenter prospective cohort study

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yanyan Wang ◽  
Wenzhe Sun ◽  
Jinfeng Miao ◽  
Xiuli Qiu ◽  
Yan Lan ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Rating Scale ◽  
Independent Predictor ◽  
Univariate Analysis ◽  
Stroke Onset ◽  
Stroke Patients ◽  
C Peptide ◽  
Post Stroke ◽  
Post Stroke Depression

Abstract Background Fasting C-peptide (FCP) has been shown to play an important role in the pathophysiology of mood disorders including depression and schizophrenia, but it is unknown whether it also predicts post-stroke depression (PSD). This study examined the association between FCP and PSD at 6 months after acute ischemic-stroke onset among Chinese subjects. Methods A total of 656 stroke patients were consecutively recruited from three hospitals of Wuhan city, Hubei province. Clinical and laboratory data were collected on admission. PSD status was evaluated by DSM-V criteria and 17-item Hamilton Rating Scale for Depression (HAMD-17) at 6 months after acute ischemic stroke. The χ2-test, Mann-Whitney U-test, and t-test were used to check for statistical significance. Multivariate logistic regression model was used to explore independent predictor of PSD. Results In the univariate analysis, significant differences were found between the PSD and non-PSD groups in terms of FCP level (p = 0.009). After multivariate adjustments, FCP remained a significant independent predictor of PSD, with an adjusted odds ratio of 1.179 (95%CI: 1.040–1.337, p = 0.010). Conclusions Higher FCP levels on admission were found to be associated with PSD at 6 months after acute ischemic-stroke onset. For stroke patients, doctors should pay attention to the baseline FCP for screening high-risk PSD in clinical practice.

scholarly journals Antiphospholipid antibodies predict post-stroke depression after acute ischemic stroke

2019 ◽  
Vol 257 ◽  
pp. 160-165 ◽  
Author(s):  
Guangli Wang ◽  
Yiting Zhou ◽  
Xiaoqing Bu ◽  
Hao Peng ◽  
Tan Xu ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Antiphospholipid Antibodies ◽  
Post Stroke ◽  
Post Stroke Depression

Post-stroke depression as a predictor of caregivers burden of acute ischemic stroke patients in China

2017 ◽  
Vol 23 (5) ◽  
pp. 541-547 ◽  
Author(s):  
Dong-Mei Dou ◽  
Ling-Ling Huang ◽  
Jin Dou ◽  
Xiao-Xiao Wang ◽  
Pei-Xi Wang
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Stroke Patients ◽  
Post Stroke ◽  
Post Stroke Depression

scholarly journals Development and Validation of 3-Month Major Post-Stroke Depression Prediction Nomogram After Acute Ischemic Stroke Onset

2021 ◽  
Vol Volume 16 ◽  
pp. 1439-1447
Author(s):  
Guo Li ◽  
Ping Jing ◽  
Guohua Chen ◽  
Junhua Mei ◽  
Jinfeng Miao ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Stroke Onset ◽  
Post Stroke ◽  
Post Stroke Depression ◽  
Development And Validation

scholarly journals The Combination of Insulin Resistance and Serum Interleukin-1β Correlates with Post-Stroke Depression in Patients with Acute Ischemic Stroke

2021 ◽  
Vol Volume 17 ◽  
pp. 735-746
Author(s):  
Xiaoyi Yi ◽  
Xiangyang Zhu ◽  
Yong Zhou ◽  
Dongmei Zhang ◽  
Mengmeng Li ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Interleukin 1Β ◽  
Post Stroke ◽  
Post Stroke Depression
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