scholarly journals Characteristic imaging features of neurovascular involvement in primary Sneddon’s syndrome: an analysis of 12 cases

2020 ◽  
Author(s):  
Ezgi Yilmaz ◽  
Ethem Murat Arsava ◽  
Rahşan Gocmen ◽  
Kader Karli Oguz ◽  
Anil Arat ◽  
...  
Keyword(s):  
Imaging Features ◽  
Sneddon's Syndrome ◽  
Sneddon’S Syndrome ◽  
Characteristic Imaging

scholarly journals Remarkable Superficial Siderosis and Microbleed Restricted in Cortex might be Responsible for Atrophy and Cognitive Decline in Sneddon’s Syndrome

2020 ◽  
Author(s):  
Ming YAO ◽  
Jiuliang Zhao ◽  
Nan Jiang ◽  
Libo Li ◽  
Jun Ni
Keyword(s):  
Cognitive Decline ◽  
White Matter Hyperintensities ◽  
Hemorrhagic Stroke ◽  
Cerebral Arteries ◽  
Cerebral Atrophy ◽  
Superficial Siderosis ◽  
Imaging Features ◽  
Sneddon's Syndrome ◽  
Sneddon’S Syndrome ◽  
Sneddon Syndrome

Abstract ObjectiveSneddon’s syndrome is a rare non-inflammatory arteriopathy affecting small and medium-sized arteries, characterized by a generalized livedo reticularis and recurrent ischemic stroke. Hemorrhagic stroke was reported in limited cases, but microbleeds and superficial siderosis were rarely issued. We aimed to investigate the hemorrhagic imaging features of Sneddon’s syndrome and explore the possible mechanism and clinical relevance.MethodsClinical data and cerebral MR imaging including T2* sequence of 7 consecutive patients with Sneddon’s syndrome were reviewed.ResultsThe most common neurological manifestations were cognitive impairment and stroke attack(71.4%), followed by seizures and movement disorder(28.6%). Cerebral microbleeds were detected in six patients on T2* sequence，four of whom presented more than 5 microbleeds. The majority of the microbleeds were predominantly cortical restricted and especially located in the cortical watersheds. Multiple superficial siderosis were identified mainly involving cortical watersheds in five cases. Significant cerebral atrophy with prominent secondary white matter hyperintensities in bilateral cortical watersheds were also observed. Abnormal tortuous and multiple focal occlusion of bilateral distal MCA were shown in one patient by DSA. No stenosis of proximal segment of cerebral arteries was detected in all the patients.ConclusionsThis is the first report illustrating abundant cortical microbleeds and superficial siderosis mainly involved the anterior and posterior cortical watersheds in Sneddon’s syndrome. The surprisingly identical topographic distribution of hemorrhagic lesions and the obvious atrophy suggest cerebral atrophy might be secondary to the microangiopathy related hemorrhagic lesions and further contribute to the neurological deficit, especially the early cognitive decline in Sneddon syndrome.

scholarly journals Imaging diagnosis of classical and new pneumoconiosis: predominant reticular HRCT pattern

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Akira Masanori
Keyword(s):  
Computed Tomography ◽  
Interstitial Lung Disease ◽  
Imaging Features ◽  
Imaging Findings ◽  
Imaging Diagnosis ◽  
High Resolution Computed Tomography ◽  
Pleural Fibrosis ◽  
Pathologic Findings ◽  
Characteristic Imaging ◽  
The Individual

AbstractOur understanding of the manifestations of pneumoconioses is evolving in recent years. Associations between novel exposures and diffuse interstitial lung disease have been newly recognized. In advanced asbestosis, two types of fibrosis are seen, probably related to dose of exposure, existence of pleural fibrosis, and the host factor status of the individual. In pneumoconiosis of predominant reticular type, nodular opacities are often seen in the early phase. The nodular pattern is centrilobular, although some in metal lung show perilymphatic distribution, mimicking sarcoidosis. High-resolution computed tomography enables a more comprehensive correlation between the pathologic findings and clinically relevant imaging findings. The clinician must understand the spectrum of characteristic imaging features related to both known dust exposures and to historically recent new dust exposures.

scholarly journals 36. Recurrent strokes in younger patient with rash: a case of Sneddon’s syndrome

2018 ◽  
Vol 2 (suppl_1) ◽  
Author(s):  
Himashi Anver ◽  
Shirish Dubey ◽  
Siwalik Banerjee ◽  
Tanya Potter ◽  
Andrew Short ◽  
...  
Keyword(s):  
Sneddon's Syndrome ◽  
Sneddon’S Syndrome ◽  
Younger Patient ◽  
Recurrent Strokes

Neuropathological findings in Sneddon's syndrome

Neurology ◽  
2003 ◽  
Vol 60 (7) ◽  
pp. 1181-1182 ◽  
Author(s):  
D. A. Hilton ◽  
D. Footitt
Keyword(s):  
Sneddon's Syndrome ◽  
Sneddon’S Syndrome

Characteristic imaging features of desmoplastic small round cell tumour

2012 ◽  
Vol 43 (1) ◽  
pp. 93-102 ◽  
Author(s):  
Vandan Caur Arora ◽  
Anita P. Price ◽  
Stephen Fleming ◽  
Michael J. Sohn ◽  
Heather Magnan ◽  
...  
Keyword(s):  
Cell Tumour ◽  
Imaging Features ◽  
Round Cell ◽  
Small Round Cell ◽  
Characteristic Imaging ◽  
Round Cell Tumour ◽  
Small Round Cell Tumour

Sneddon's Syndrome

1999 ◽  
Vol 11 (1) ◽  
pp. 62
Author(s):  
Kyoung-Ae Jang ◽  
Man-Heui Han ◽  
Jee-Ho Choi ◽  
Kyung-Jeh Sung ◽  
Kee-Chan Moon ◽  
...  
Keyword(s):  
Sneddon's Syndrome ◽  
Sneddon’S Syndrome

Sneddon's syndrome

2009 ◽  
Vol 283 (1-2) ◽  
pp. 252
Author(s):  
J.L. De Reuck
Keyword(s):  
Sneddon's Syndrome ◽  
Sneddon’S Syndrome

A combination of livedo racemosa, occlusion of cerebral blood vessels, and nephropathy: Kidney involvement in sneddon's syndrome

1995 ◽  
Vol 26 (3) ◽  
pp. 511-515 ◽  
Author(s):  
Hiroshi Ohtani ◽  
Hirokazu Imai ◽  
Tadashi Yasuda ◽  
Hideki Wakui ◽  
Atsushi Komatsuda ◽  
...  
Keyword(s):  
Blood Vessels ◽  
Cerebral Blood Vessels ◽  
Livedo Racemosa ◽  
Sneddon's Syndrome ◽  
Sneddon’S Syndrome ◽  
Kidney Involvement

scholarly journals Ultrasound imaging of acute scrotum: Pictorial review with etiological correlation

2020 ◽  
pp. 90-109
Author(s):  
Anitha Mandava ◽  
Veeraiah Koppula ◽  
Rohit Yalamanchili ◽  
Dilip Yadav ◽  
Juluri Rakesh
Keyword(s):  
Color Doppler ◽  
Acute Scrotum ◽  
Imaging Features ◽  
First Line ◽  
Surgical Exploration ◽  
Pictorial Review ◽  
Pictorial Essay ◽  
Characteristic Imaging ◽  
Line Imaging ◽  
Urological Emergencies

High resolution ultrasound with color Doppler is the first-line imaging investigation in the evaluation of acute scrotum. It plays a crucial role in distinguishing urological emergencies necessitating immediate surgical exploration from those that can be managed conservatively. Acute scrotal pathologies can involve the scrotal sac or its contents like testis, epididymis and testicular appendages and could range from benign, self-limiting conditions to emergencies. In this pictorial essay, we briefly review the ultrasonographic technique, scrotal anatomy and characteristic imaging features of various pathologies presented as acute scrotum.

scholarly journals Therapeutic Perspectives in Sneddon’s Syndrome

2021 ◽  
Vol 18 (5) ◽  
pp. 73-80
Author(s):  
Oana-Petronela Oancea ◽  
Alexandru-Dan Costache ◽  
Daniela Olaru ◽  
Răzvan Platon ◽  
Florin Mitu
Keyword(s):  
Chronic Disease ◽  
Disease Progression ◽  
Oral Anticoagulant ◽  
Oral Anticoagulant Therapy ◽  
Protein Z ◽  
Livedo Racemosa ◽  
Sneddon's Syndrome ◽  
Sneddon’S Syndrome ◽  
Cerebrovascular Events ◽  
Therapeutic Perspective

Abstract Sneddon’s syndrome is a rare but severe progressive chronic disease, characterized by multiple discoloration skin patches called Livedo racemosa and recurrent cerebrovascular events. It mainly affects women aged around 40. Considering the two main forms, antiphospholipid (APS) positive and negative, the available treatments are directed at either one of them. The idiopathic form (APS negative) is associated with a more severe prognosis as chronic oral anticoagulant therapy (COA) is more difficult to manage. One therapeutic perspective in controlling disease progression in these patients is by understanding the protein Z deficiency in these patients as a deciding factor in the success of the COA therapy.

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