Impact of intense pulse light irradiation on BALB/c mouse skin—in vivo study on collagens, matrix metalloproteinases and vascular endothelial growth factor

2007 ◽  
Vol 24 (1) ◽  
pp. 101-108 ◽  
Author(s):  
Dan Luo ◽  
Yan Cao ◽  
Di Wu ◽  
Yang Xu ◽  
Bin Chen ◽  
...  
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Matrix Metalloproteinases ◽  
Mouse Skin ◽  
Light Irradiation ◽  
In Vivo Study ◽  
Intense Pulse Light ◽  
Vascular Endothelial ◽  
Endothelial Growth Factor

scholarly journals Role of vascular endothelial growth factor in inducing production of angiopoetin-1 – in vivo study in Fisher rats

2017 ◽  
Vol 68 (4) ◽  
pp. 326-329
Author(s):  
Piotr Barć ◽  
Tomasz Płonek ◽  
Dagmara Baczyńska ◽  
Artur Pupka ◽  
Wojciech Witkiewicz ◽  
...  
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
In Vivo Study ◽  
Vascular Endothelial ◽  
Angiopoetin 1 ◽  
Endothelial Growth Factor

scholarly journals Cross-Talk between Vascular Endothelial Growth Factor and Matrix Metalloproteinases in the Induction of Neovascularization in Vivo

2010 ◽  
Vol 176 (1) ◽  
pp. 496-503 ◽  
Author(s):  
Quteba Ebrahem ◽  
Shyam S. Chaurasia ◽  
Amit Vasanji ◽  
Jian Hua Qi ◽  
Phillip A. Klenotic ◽  
...  
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Matrix Metalloproteinases ◽  
Cross Talk ◽  
Vascular Endothelial ◽  
Endothelial Growth Factor

scholarly journals Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting

2007 ◽  
Vol 204 (6) ◽  
pp. 1431-1440 ◽  
Author(s):  
Maria Wirzenius ◽  
Tuomas Tammela ◽  
Marko Uutela ◽  
Yulong He ◽  
Teresa Odorisio ◽  
...  
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Lymphatic Vessel ◽  
Lymphatic Vessels ◽  
Mouse Skin ◽  
Vegf Receptor ◽  
Vascular Endothelial ◽  
Factor C ◽  
Endothelial Growth Factor

Lymphatic vessel growth, or lymphangiogenesis, is regulated by vascular endothelial growth factor-C (VEGF-C) and -D via VEGF receptor 3 (VEGFR-3). Recent studies suggest that VEGF, which does not bind to VEGFR-3, can also induce lymphangiogenesis through unknown mechanisms. To dissect the receptor pathway that triggers VEGFR-3–independent lymphangiogenesis, we used both transgenic and adenoviral overexpression of placenta growth factor (PlGF) and VEGF-E, which are specific activators of VEGFR-1 and -2, respectively. Unlike PlGF, VEGF-E induced circumferential lymphatic vessel hyperplasia, but essentially no new vessel sprouting, when transduced into mouse skin via adenoviral vectors. This effect was not inhibited by blocking VEGF-C and -D. Postnatal lymphatic hyperplasia, without increased density of lymphatic vessels, was also detected in transgenic mice expressing VEGF-E in the skin, but not in mice expressing PlGF. Surprisingly, VEGF-E induced lymphatic hyperplasia postnatally, and it did not rescue the loss of lymphatic vessels in transgenic embryos where VEGF-C and VEGF-D were blocked. Our data suggests that VEGFR-2 signals promote lymphatic vessel enlargement, but unlike in the blood vessels, are not involved in vessel sprouting to generate new lymphatic vessels in vivo.

scholarly journals In Vivo Detection of Human Vascular Endothelial Growth Factor Promoter Activity in Transgenic Mouse Skin

2000 ◽  
Vol 157 (1) ◽  
pp. 103-110 ◽  
Author(s):  
Jiro Kishimoto ◽  
Ritsuko Ehama ◽  
Yimin Ge ◽  
Takashi Kobayashi ◽  
Toshio Nishiyama ◽  
...  
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Transgenic Mouse ◽  
Promoter Activity ◽  
Mouse Skin ◽  
Vascular Endothelial ◽  
In Vivo Detection ◽  
Endothelial Growth Factor
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