scholarly journals Short- and long-term outcomes of endoscopic submucosal dissection for early gastric cancer in elderly patients aged 75 years and older

2016 ◽  
Vol 20 (3) ◽  
pp. 489-495 ◽  
Author(s):  
Tetsuya Sumiyoshi ◽  
Hitoshi Kondo ◽  
Ryoji Fujii ◽  
Takeyoshi Minagawa ◽  
Shinya Fujie ◽  
...  

Endoscopy ◽  
2013 ◽  
Vol 45 (09) ◽  
pp. 703-707 ◽  
Author(s):  
Seiichiro Abe ◽  
Ichiro Oda ◽  
Haruhisa Suzuki ◽  
Satoru Nonaka ◽  
Shigetaka Yoshinaga ◽  
...  


2017 ◽  
Vol 32 (4) ◽  
pp. 1963-1970 ◽  
Author(s):  
Hye Kyung Jeon ◽  
Seong Jun Lee ◽  
Gwang Ha Kim ◽  
Do Youn Park ◽  
Bong Eun Lee ◽  
...  


2018 ◽  
Vol 54 (6) ◽  
pp. 511-520 ◽  
Author(s):  
Yohei Yabuuchi ◽  
Naomi Kakushima ◽  
Kohei Takizawa ◽  
Masaki Tanaka ◽  
Noboru Kawata ◽  
...  


Cancers ◽  
2021 ◽  
Vol 13 (14) ◽  
pp. 3598
Author(s):  
Ga Hee Kim ◽  
Kee Don Choi ◽  
Yousun Ko ◽  
Taeyong Park ◽  
Kyung Won Kim ◽  
...  

Background/Aim: We investigated the oncologic outcomes in elderly patients who underwent endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) by focusing on the impact of comorbidities, sarcopenia, and nutritional status. Methods: Between 2005 and 2016, 280 patients aged ≥ 80 years with 289 EGCs underwent ESD at a tertiary care center. The short- and long-term survival outcomes were assessed. Cox regression analysis was used to identify factors associated with survival, including clinicopathologic factors and abdominal muscle area measured by computed tomography. Results: The rates of en bloc, R0, and, curative resection were 99.3%, 90.0%, and 69.2%, respectively. The rates of post-ESD bleeding and perforation rates were 2.1% and 3.1%, respectively, and no cases showed significant life-threatening adverse events. Over a median follow-up period of 70.5 months, the 3- and 5-year overall survival (OS) rates were 89.5% and 77.1%, respectively; of the114 patients who died, only four (3.5%) were due to gastric cancer. A total of 173 (61.8%) had sarcopenia, and they had lower rates of 3-year (88.4% vs. 91.4%) and 5-year (73.1% vs. 84.0%; p = 0.046) OS than did those without sarcopenia. In multivariable analyses, prognostic nutritional index (hazard ratio [HR], 0.93; 95% confidence interval [CI]: 0.90–0.98; p = 0.002) and Charlson comorbidity index (HR 1.19; 95% CI: 1.03–1.37; p = 0.018) were significant factors associated with overall survival. Conclusions: ESD was a feasible and safe therapeutic method to use in elderly patients, whose long-term survival was significantly associated with nutritional status and comorbidities. These results suggest the need for a possible extension of the curative criteria for ESD in elderly patients with EGC.



2018 ◽  
Vol 22 (4) ◽  
pp. 838-844 ◽  
Author(s):  
Yosuke Toya ◽  
Masaki Endo ◽  
Shotaro Nakamura ◽  
Risaburo Akasaka ◽  
Shunichi Yanai ◽  
...  


2019 ◽  
Vol 31 (4) ◽  
pp. 418-424 ◽  
Author(s):  
Mohamed M. Abdelfatah ◽  
Mohamed Barakat ◽  
Dina Ahmad ◽  
Mariam Ibrahim ◽  
Yahia Ahmed ◽  
...  


2013 ◽  
Vol 26 (2) ◽  
pp. 214-219 ◽  
Author(s):  
Ichiro Oda ◽  
Tsuneo Oyama ◽  
Seiichiro Abe ◽  
Ken Ohnita ◽  
Takashi Kosaka ◽  
...  


2015 ◽  
Vol 81 (5) ◽  
pp. AB124-AB125
Author(s):  
Satoshi Tanabe ◽  
Kenji Ishido ◽  
Takashi Kosaka ◽  
Haruhisa Suzuki ◽  
Junko Fujisaki ◽  
...  




Sign in / Sign up

Export Citation Format

Share Document