scholarly journals Surgical management of symptomatic cavum septum pellucidum cysts: systematic review of the literature

2020 ◽  
Author(s):  
Alexandre Simonin ◽  
Christopher R. P. Lind
Keyword(s):  
Systematic Review ◽  
Surgical Procedure ◽  
Psychiatric Symptoms ◽  
Obstructive Hydrocephalus ◽  
Treatment Options ◽  
Postoperative Outcome ◽  
Septum Pellucidum ◽  
Cavum Septum Pellucidum ◽  
Female Ratio ◽  
Pubmed Database

AbstractCavum septum pellucidum (CSP) and cavum vergae (CV) cysts are commonly found incidentally. They are usually asymptomatic but may present with symptoms related to obstructive hydrocephalus. There is no consensus about the management of symptomatic CSP and CV cysts. We present, to the best of our knowledge, the first systematic review of the different treatment options for symptomatic CSP and CV cysts. We conducted a literature review using PubMed database, searching for cases of symptomatic CSP and CV cysts managed surgically, and published until April 2019. Preoperative characteristics, surgical procedure, and postoperative outcome were analyzed using SPSS® software (Statistical Package for Social Sciences, IBM®). We found 54 cases of symptomatic CSP and CV cysts managed surgically (34 males, 20 females, 1.7/1 male to female ratio). Mean age was 24.3 ± 20.1 years. The most common presentation was headaches (34 patients, 62%), followed by psychiatric symptoms (27 patients, 49.1%). Preoperative radiological hydrocephalus was present in 30 patients (54.5%). The most common surgical procedure was endoscopic fenestration (39 patients, 70.9%), followed by shunting (10 patients, 18.2%), open surgery (3 patients, 5.5%), and stereotactic fenestration (1 patient, 1.8%). Complete resolution of symptoms was achieved in 36 patients (65.5%) and partial resolution in 7 patients (12.7%), and symptoms were unchanged in 2 patients. The present review suggests that surgical treatment could provide resolution of the symptoms in most of the cases, regardless of the procedure performed. Although mean follow-up was short among the studies, recurrence rate was low.

scholarly journals Characteristics and treatment effectiveness of the nummular headache: a systematic review and analysis of 110 cases

2020 ◽  
Vol 2 (1) ◽  
pp. e000049
Author(s):  
Urvish K Patel ◽  
Sidra Saleem ◽  
Arsalan Anwar ◽  
Preeti Malik ◽  
Bindi Chauhan ◽  
...  
Keyword(s):  
Systematic Review ◽  
Complete Resolution ◽  
Rating Scale ◽  
Botulinum Toxin Type A ◽  
Treatment Options ◽  
Correct Diagnosis ◽  
Primary Headache ◽  
Tricyclic Antidepressant ◽  
Nummular Headache ◽  
Pubmed Database

Background/objectiveNummular headache (NH) is a primary headache disorder characterised by intermittent or continuous scalp pain, affecting a small circumscribed area of the scalp. As there are limited data in the literature on NH, we conducted this review to evaluate demographic characteristics and factors associated with complete resolution of the headache, and effectiveness of treatment options.MethodsWe performed a systematic review of cases reported through PubMed database, using Preferred Reporting Items for Systematic Reviews and Meta-Analyses protocol and ‘nummular headache’, ‘coin-shaped headache’ and ‘coin-shaped cephalalgia’ keywords. Analysis was performed by using χ2 test and Wilcoxon rank-sum test. For individual interventions, the response rate (RR%) of the treatment was calculated.ResultsWe analysed a total of 110 NH cases, with median age 47 years and age of pain onset 42 years. Median duration to make correct diagnosis was 18 months after first attack. The median intensity of each attack was 5/10 on verbal rating scale over 4 cm diameter with duration of attack <30 min. Patients with NH had median three attacks per day with frequency of 9.5 days per month. 40 (57.97%) patients had complete resolution of the headache after treatment. Patients with complete resolution were younger, more likely to be female, and were more likely to have diagnosis within year. Patients with complete resolution more likely to have received treatment with onabotulinum toxin A (botulinum toxin type A (BoNT-A)), and gabapentin compared with patients without complete resolution. Most effective interventions were gabapentin (n=34; RR=67.7%), non-steroidal anti-inflammatory drugs (NSAIDs) (n=32; RR=65.6%), BoNT-A (n=12; RR=100%) and tricyclic antidepressant (n=9; RR=44.4%).ConclusionYounger patients, female sex and early diagnosis were associated with complete resolution. NSAIDs, gabapentin and BoNT-A were most commonly used medications, with significant RRs.

Endoscopic Fenestration of Cavum Septum Pellucidum Cysts to the Third Ventricle: Technical Note

2020 ◽  
Vol 19 (4) ◽  
pp. E434-E439
Author(s):  
Alexandre Simonin ◽  
Omar Bangash ◽  
Arjun S Chandran ◽  
Erik Uvelius ◽  
Christopher Lind
Keyword(s):  
Surgical Procedure ◽  
Clinical Presentation ◽  
Third Ventricle ◽  
Technical Note ◽  
Septum Pellucidum ◽  
Imaging Studies ◽  
Foramen Of Monro ◽  
Cavum Septum Pellucidum ◽  
The Third ◽  
Endoscopic Fenestration

Abstract BACKGROUND AND IMPORTANCE Cavum septum pellucidum (CSP) and cavum vergae (CV) cysts are common incidental findings on imaging studies. However, they may rarely present with symptoms related to the obstruction of the foramen of Monro by the cyst leaflets. There is no consensus regarding the management of symptomatic CSP and CV cysts. We present an original transcavum interforniceal endoscopic fenestration technique. The step-by-step surgical procedure and two illustrative cases are presented. CLINICAL PRESENTATION A 31-yr-old male and a 24-yr-old woman presented with symptomatic CSP and CV cysts. For both patients, neuronavigation was used to plan the procedure. An endoscope was introduced into the cyst through a right frontal burr-hole. After an examination of the endoscopic anatomy, a communication between the cyst and the third ventricle was performed using an endoscopic forceps. In both cases, directly after the fenestration, cerebrospinal fluid (CSF) passed through the communication, and the collapse of the cyst was appreciated. Symptoms were relieved in both patients, and neuropsychological assessment improved. Postoperative imaging showed a reduction in the cyst bulge, and patent foramen of Monro. CONCLUSION Endoscopic fenestration of CSP and CV cysts to the third ventricle through an interforniceal navigated approach is a feasible and efficient surgical procedure. Theoretical advantages include a single tract through noneloquent brain, a perpendicular trajectory to the membrane for fenestration, and a large CSF space beyond the fenestration point.

Are cavum septum pellucidum abnormalities more common in schizophrenia spectrum disorders? A systematic review and meta-analysis

2011 ◽  
Vol 125 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Clarissa Trzesniak ◽  
Irismar R. Oliveira ◽  
Matthew J. Kempton ◽  
Amanda Galvão-de Almeida ◽  
Marcos H.N. Chagas ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Septum Pellucidum ◽  
Schizophrenia Spectrum Disorders ◽  
Cavum Septum Pellucidum ◽  
Schizophrenia Spectrum ◽  
Spectrum Disorders

Dorsal Dupuytren’s disease: a systematic review of published cases and treatment options

2019 ◽  
Vol 44 (9) ◽  
pp. 963-971 ◽  
Author(s):  
Raphael Carloni ◽  
Silvia Gandolfi ◽  
Benedicte Elbaz ◽  
Albane Bonmarchand ◽  
Roberto Beccari ◽  
...  
Keyword(s):  
Systematic Review ◽  
Functional Result ◽  
Treatment Options ◽  
Proximal Interphalangeal Joint ◽  
Dupuytren’S Disease ◽  
Level Of Evidence ◽  
Dupuytren's Disease ◽  
Female Ratio ◽  
Knuckle Pads ◽  
Male To Female

Dorsal lesions in Dupuytren’s disease are rare and data concerning their epidemiology and management are sparse. We conducted a systematic review to summarize reported cases of dorsal Dupuytren’s disease. Pubmed, Cochrane, and Embase databases were searched from 1893 to 2018, and 17 articles were selected (525 patients). The male to female ratio was 3.8:1. The dorsal disease was bilateral in 225 patients (50%). The index was the most commonly affected finger (48 patients). The proximal interphalangeal joint was the most commonly affected (484 cases). The most frequently reported lesions were knuckle pads (503 patients), dorsal nodules between interphalangeal joints (14 patients), boutonnière deformities (12 patients), and swan-neck deformities (2 patients). Nearly half of the included patients were treated surgically. Postoperative functional result depended on the treated lesion. Most of the included studies had a low level of evidence. Higher-quality studies are necessary to confirm our findings.

scholarly journals Autologous matrix-induced chondrogenesis for the treatment of osteochondral lesions of the talus: A systematic review

2021 ◽  
Vol 12 (4) ◽  
Author(s):  
Michael-Alexander Malahias ◽  
Lazaros Kostretzis ◽  
Panayiotis D. Megaloikonomos ◽  
Erwin-Brian Cantiller ◽  
Dimitrios Chytas ◽  
...  
Keyword(s):  
Systematic Review ◽  
Systematic Reviews ◽  
Postoperative Outcome ◽  
Osteochondral Lesions ◽  
Mean Values ◽  
Cochrane Database ◽  
Pubmed Database ◽  
Functional Scores ◽  
Significant Clinical Improvement ◽  
Meta Analyses

This study was performed to determine whether Autologous Matrix-Induced Chondrogenesis (AMIC) is an effective and safe treatment option for patients with symptomatic Osteochondral defects of the Talus (OCTs) and to identify factors that influence the clinical outcome. A systematic review of the literature was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Three reviewers independently conducted the literature search using the MEDLINE/PubMed database and the Cochrane Database of Systematic Reviews. The databases were queried using the terms “autologous” AND “matrix” AND “induced” AND “chondrogenesis.” Thirteen studies were eligible for review. All studies that compared the preoperative and postoperative mean values of different clinical/functional scores showed significant clinical improvement. The final postoperative mean Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) score ranged from 50.9 to 74.5. The included studies indicated that age and body mass index may have a detrimental impact on the postoperative outcome. A higher re-intervention rate is expected with the open technique, mainly because of hardware removal after malleolar osteotomy. This data analysis demonstrated that both arthroscopic and open AMIC procedures are effective and safe for the treatment of OCTs. Level IV, systematic review of therapeutic studies.

Treatment-resistant childhood-onset schizophrenia and abnormally enlarged cavum septum pellucidum combined with cavum vergae: case report and literature review

2011 ◽  
Vol 26 (S2) ◽  
pp. 1402-1402
Author(s):  
S.-H. Hu ◽  
Z.-L. Liao ◽  
M.-M. Zhang ◽  
Y. Xu
Keyword(s):  
Psychiatric Symptoms ◽  
Auditory Hallucination ◽  
Diagnostic Errors ◽  
Septum Pellucidum ◽  
Medical Conditions ◽  
Childhood Onset ◽  
Cavum Septum Pellucidum ◽  
Cavum Vergae ◽  
Childhood Onset Schizophrenia ◽  
Worse Prognosis

The treatment of refractory schizophrenia has been a clinical challenge for most psychiatrists. The possible mechanism of the refractory schizophrenia included diagnostic errors, medical conditions and brain dysgensis. Here, we described a patient with childhood-onset schizophrenia who had severe psychiatric symptoms such as auditory hallucination and persecutory delusion and so on. We reexamined all his possible medical conditions and found the patient had an abnormal enlarged Cavus Septum Pellucidum (CSP) combined with Cavum Vergae (CV) (maximum length>30 mm). Some reports suggested that abnormal CSP(length>6 mm) has an significant association with schizophrenia. However, abnormally large CSP or CSP/CV and related prognosis were reported rarely. This case suggested that abnormally enlarged CSP or CSP/CV may lead to schizophrenia and worse prognosis.

scholarly journals Treating chronic diarrhea: A systematic review on Immunoproliferative Small Intestinal Disease (IPSID)

PLoS ONE ◽  
2021 ◽  
Vol 16 (7) ◽  
pp. e0253695
Author(s):  
Daniele Evangelista-Leite ◽  
Breno Affonso Madaloso ◽  
Bruno Shouta Yamashita ◽  
Francesco Enrico Aloise ◽  
Lucas Polito Verdasca ◽  
...  
Keyword(s):  
Systematic Review ◽  
Chronic Diarrhea ◽  
B Cell Lymphoma ◽  
Intestinal Disease ◽  
Disease Stage ◽  
Female Ratio ◽  
Pubmed Database ◽  
Immunoproliferative Small Intestinal Disease ◽  
Small Intestinal ◽  
Small Intestinal Disease

Immunoproliferative Small Intestinal Disease (IPSID) is a disease characterized by extra-nodal marginal zone B-cell lymphoma with villous atrophy in the small intestine, causing chronic intermittent non-bloody diarrhea. Although originally associated with the Mediterranean region, this disease is present in many countries worldwide and may have been underreported due to its complicated diagnosis and scarce scientific literature, especially in regards to treatment. This study aims to review IPSID clinical features, therapeutic options, and treatment outcomes to help physicians identify and treat IPSID. Using PRISMA guidelines, a systematic review of articles was conducted on PubMed database with search terms including IPSID, therapy, treatment, and outcomes. Inclusion and exclusion criteria were used to select 33 English language articles published from the year 2000–2020 that included relevant clinical information about IPSID treatment. Data were extracted independently by at least two authors to reduce the introduction of potential bias. There were 22 case reports, 7 reviews, 1 research article, 1 prospective study, 1 letter to the editor and 1 memoriam in which 76 patients were identified. Epidemiological analysis showed a mean patient age of 32 years old, 2.4:1 mal to female ratio and heterogeneous ethnicities, with 16 Europeans (43.2%) and 12 Asians (32.4%). Chief symptoms included chronic diarrhea (53/76, 69.7%), weight loss (49/76, 64.4%), malabsorption (38/76, 50%), abdominal pain (32/76, 42.1%), and finger clubbing (24/76, 31.6%). Patients stratified into the early disease stage (Galian A) were treated with tetracycline antibiotics, corticosteroids, and non-pharmacological supplements with mostly with complete or partial remission. Late stages (Galian B or C), were treated mostly with anthracycline-based chemotherapy, and occasionally surgery, radiotherapy, or rituximab. This work offers a targeted approach to diagnosing and treating IPSID to aid physicians and serve as a treatment guideline recommendation for future public policies and clinical studies.

scholarly journals Percutaneous cholecystostomy… why, when, what next? A systematic review of past decade

2018 ◽  
Vol 100 (8) ◽  
pp. 618-631
Author(s):  
M Elsharif ◽  
A Forouzanfar ◽  
K Oaikhinan ◽  
Niraj Khetan
Keyword(s):  
Systematic Review ◽  
Technological Development ◽  
Treatment Options ◽  
Vital Role ◽  
Bridge To Surgery ◽  
Percutaneous Cholecystostomy ◽  
Tube Drainage ◽  
Pubmed Database ◽  
Cholecystostomy Tube ◽  
Percutaneous Cholecystostomy Tube

IntroductionPercutaneous cholecystostomy tube drainage has played a vital role in management of cholecystitis in patients where surgery is not appropriate. However, management differs from unit to unit and even between different consultants in the same unit. We conducted this systematic review to understand which of these resulted in the best patient outcomes.MethodsWe conducted a systematic review using the PubMed database for publication between January 2006 to December 2016. Keyword variants of ‘cholecystostomy’ and ‘cholecystitis’ were combined to identify potential relevant papers for inclusion.FindingsWe identified 46 studies comprising a total of 312,085 patients from 20 different countries. These papers were reviewed, critically appraised and summarised in table format. Percutaneous cholecystostomy tube drainage is an important treatment modality with an excellent safety profile. It has been used successfully both as a definitive procedure and as a bridge to surgery. There continues to be great variation, however, when it comes to the indications, timing and management of these drains. As far as we are aware, this is the only systematic review to cover the past 10 years. It provides a much-needed update, considering all the technological development and new treatment options in laparoscopic surgery and interventional radiology.

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