A potential lignan botanical insecticide from Phryma leptostachya against Aedes aegypti: laboratory selection, metabolic mechanism, and resistance risk assessment

Author(s):  
Xingtao Qie ◽  
Anqi Sun ◽  
Huanhuan Hao ◽  
Bo Lv ◽  
Wenjun Wu ◽  
...  
2020 ◽  
Vol 49 (1) ◽  
pp. 45-54
Author(s):  
Thiago Andre Santos de Andrade ◽  
Ivanise Maria de Santana ◽  
George Chaves Jimenez ◽  
Eulina Tereza Nery Farias ◽  
Lucia Oliveira de Macedo ◽  
...  

The control of Aedes aegypti has been considered one of the most important public health challenges worldwide. Chemical compounds have long been used for this purpose, but resistance to these molecules has also increased. Therefore, over the last few years several studies have focused on the development of alternative tools, particularly those based on plant metabolites. The purpose of this study was to assess the larvicidal activity of Caesalpinia ferrea and Lippia origanoides against Ae. aegypti. Larvae (L3) of Ae. aegypti Liverpool and Rockefeller strains, as well as of the Recife population were exposed to different concentrations  of C. ferrea (ranging from 13.1 to 105 mg/mL) and L. origanoides (ranging from 16.3 to 130 mg/mL), and the mortality rate was evaluated up to 48 hours after the beginning of the experiment. All tested groups and  ontrol group were quadruplicated. For C. ferrea, mortality ranged from 42.5% to 100% for Ae. aegypti Liverpool strain,from 67% to 100% for Ae. aegypti Rockfeller strain, and 57% to 100% for Ae. aegypti Recife population after 48 hours of larval exposure. For L. origanoides, the larvicidal activity ranged from 75% to 100% for Ae. aegypti Liverpool strain, from 61.5% to 100% for Ae. aegypti Rockfeller strain, and from 60.5% to 100% for Ae.aegypti Recife population. The hydro ethanol extract of C. ferrea and L. origanoides presented larvicidal activity against Ae. aegypti.KEY WORDS: Aedes aegypti; hydro ethanol extracts; Caesalpinia ferrea; Lippia sidoides; botanical insecticide; mosquitoes.


Author(s):  
Antonio Velazquez ◽  
R. Andrew Swartz

The study of efficiency and safety for wind turbine structures under variable operating conditions is increasingly important for wind turbine design. Optimum aerodynamic performance of a wind turbine demands that serviceability effects and ultimate strength loads remain under safety design limits. From the perspective of wind turbine efficiency, variations in wind speed causes bluffing effects and vortex shedding that lead to vibration intensities in the longitudinal and transversal direction that can negatively impact aerodynamic performance of the turbine. From the perspective of wind turbine safety, variations in loading may lead to transient internal loads that threaten the safety of the structure. Inertial effects and asynchronous delays on rotational-force transmission may generate similar hazards. Monitoring and controlling displacement limits and load demands at critical tower locations can improve the efficiency of wind power generation, not to mention the structural performance of the turbine from both a strength and serviceability point of view. In this study, a probabilistic monitoring approach is developed to measure the response of the combined tower/nacelle/blade system to stochastic loading, estimate peak demand, and compare that demand to building code-derived estimates of structural resistance. Risk assessment is performed for the effects of along and across-wind forces in a framework of quantitative risk analysis with the goal of developing a near real-time estimate of structural risk that may be used to monitor safety and serviceability of the structure as well as regulate the aggressiveness of the controller that commands the blade angle of attack. To accomplish this goal, a numerical simulation of the aerodynamic performance of a wind turbine (including blades, the nacelle and the tower) is analyzed to study the interaction between the structural system and incoming flow. A model based on distributed-stationary random wind load profile for the combined along-wind and across-wind responses is implemented in Matlab to simulate full aero-elastic dynamic analysis to simulate tower with nacelle, hub, rotor and tower substructures. Self-weight, rotational, and axial effects of the blades, as well as lateral resistance of substructure elements are incorporated in the finite element model, including vortex-shedding effects on the wake zone. Reliability on the numerical solution is inspected on the tower structure by comparing the numerical solution with established experimental-analytical procedures.


2002 ◽  
Vol 58 (9) ◽  
pp. 935-938 ◽  
Author(s):  
Udo Heimbach ◽  
Gregor Kral ◽  
Peter Niemann

2015 ◽  
Vol 108 (6) ◽  
pp. 2711-2719 ◽  
Author(s):  
Oderlei Bernardi ◽  
Daniel Bernardi ◽  
Douglas Amado ◽  
Renan S. Sousa ◽  
Julio Fatoretto ◽  
...  

2020 ◽  
Vol 77 (1) ◽  
pp. 538-547
Author(s):  
Wenchan Chen ◽  
Lingling Wei ◽  
Weicheng Zhao ◽  
Bingran Wang ◽  
Huanhuan Zheng ◽  
...  

2017 ◽  
Vol 4 (2) ◽  
pp. 23
Author(s):  
Tisa Rizkika Nur Amelia

<p>The aim of the research were to evaluate the efficacy of botanical insecticide of <em>S. mahagoni </em>leaves extracts against larvae of <em>Ae. aegypti,</em> based on concentration of the leaves <em>S. mahagoni </em>extract, and in additional to determine secondary metabolites compounds of <em>S. mahagoni </em>leaves extract. The extraction of <em>S. mahagoni </em>leaves was done by using ethanol solvents and than was analyzed by using Thin Layer Chromatography. The result indicated that ethanolic extract of <em>S. mahagoni </em>leaf contained alkaloid, tannin, saponin, terpenoid, and flavonoid compounds. The value of LC<sub>50 </sub>and LC<sub>90</sub> calculation showed that LC<sub>50</sub> of ethanolic extract over second and third instar larvae respectively were 488 ppm and 644 ppm. However the value of LC<sub>90</sub> of both instar larvae were 732 ppm and 797 ppm. Based on the above result, it can be concluded that ethanolic extract of <em>S. mahagoni </em>leaf was effective against larvae of <em>Ae .aegypti</em>.</p><p>Key words: <em>Ae. aegypti</em>, <em>S. mahagoni</em>, botanical insecticide</p>


2019 ◽  
Vol 156 ◽  
pp. 123-128 ◽  
Author(s):  
Jian Hu ◽  
Yuxin Zhou ◽  
Tao Gao ◽  
Jiamei Geng ◽  
Yuan Dai ◽  
...  

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