IGBT-Based Pulsed Electric Fields Generator for Disinfection: Design and In Vitro Studies on Pseudomonas aeruginosa

2019 ◽  
Vol 47 (5) ◽  
pp. 1314-1325 ◽  
Author(s):  
Andrey Ethan Rubin ◽  
Klimenty Levkov ◽  
Osman Berk Usta ◽  
Martin Yarmush ◽  
Alexander Golberg
2017 ◽  
Vol 231 ◽  
pp. 165-174 ◽  
Author(s):  
Ya-Fei Liu ◽  
Indrawati Oey ◽  
Phil Bremer ◽  
Patrick Silcock ◽  
Alan Carne

2010 ◽  
Vol 54 (8) ◽  
pp. 3212-3218 ◽  
Author(s):  
Moshe Giladi ◽  
Yaara Porat ◽  
Alexandra Blatt ◽  
Esther Shmueli ◽  
Yoram Wasserman ◽  
...  

ABSTRACT High-frequency, low-intensity electric fields generated by insulated electrodes have previously been shown to inhibit bacterial growth in vitro. In the present study, we tested the effect of these antimicrobial fields (AMFields) on the development of lung infection caused by Pseudomonas aeruginosa in mice. We demonstrate that AMFields (10 MHz) significantly inhibit bacterial growth in vivo, both as a stand-alone treatment and in combination with ceftazidime. In addition, we show that peripheral (skin) heating of about 2°C can contribute to bacterial growth inhibition in the lungs of mice. We suggest that the combination of alternating electric fields, together with the heat produced during their application, may serve as a novel antibacterial treatment modality.


PLoS ONE ◽  
2018 ◽  
Vol 13 (5) ◽  
pp. e0196688 ◽  
Author(s):  
Yuchen Zhang ◽  
Feihong Dong ◽  
Zhengxin Liu ◽  
Jinsong Guo ◽  
Jue Zhang ◽  
...  

1993 ◽  
Vol 14 (S2) ◽  
pp. 1-73 ◽  
Author(s):  
Martin Misakian ◽  
Asher R. Sheppard ◽  
David Krause ◽  
Marvin E. Frazier ◽  
Douglas L. Miller

Marine Drugs ◽  
2021 ◽  
Vol 19 (12) ◽  
pp. 662
Author(s):  
Natalia Castejón ◽  
Kristin Anna Thorarinsdottir ◽  
Ragnhildur Einarsdóttir ◽  
Kristberg Kristbergsson ◽  
Gudrún Marteinsdóttir

A growing concern for overall health is driving a global market of natural ingredients not only in the food industry but also in the cosmetic field. In this study, a screening on potential cosmetic applications of aqueous extracts from three Icelandic seaweeds produced by pulsed electric fields (PEF) was performed. Produced extracts by PEF from Ulva lactuca, Alaria esculenta and Palmaria palmata were compared with the traditional hot water extraction in terms of polyphenol, flavonoid and carbohydrate content. Moreover, antioxidant properties and enzymatic inhibitory activities were evaluated by using in vitro assays. PEF exhibited similar results to the traditional method, showing several advantages such as its non-thermal nature and shorter extraction time. Amongst the three Icelandic species, Alaria esculenta showed the highest content of phenolic (mean value 8869.7 µg GAE/g dw) and flavonoid (mean value 12,098.7 µg QE/g dw) compounds, also exhibiting the highest antioxidant capacities. Moreover, Alaria esculenta extracts exhibited excellent anti-enzymatic activities (76.9, 72.8, 93.0 and 100% for collagenase, elastase, tyrosinase and hyaluronidase, respectively) for their use in skin whitening and anti-aging products. Thus, our preliminary study suggests that Icelandic Alaria esculenta-based extracts produced by PEF could be used as potential ingredients for natural cosmetic and cosmeceutical formulations.


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