CAGE, a cancer/testis antigen, induces c-FLIPL and Snail to enhance cell motility and increase resistance to an anti-cancer drug

2009 ◽  
Vol 31 (7) ◽  
pp. 945-952 ◽  
Author(s):  
Youngmi Kim ◽  
Hyunmi Park ◽  
Dooil Jeoung
Keyword(s):  
Cell Motility ◽  
Cancer Drug ◽  
Cancer Testis Antigen ◽  
Anti Cancer ◽  
Cancer Testis

scholarly journals Role of HDAC3-miRNA-CAGE Network in Anti-Cancer Drug-Resistance

2018 ◽  
Vol 20 (1) ◽  
pp. 51 ◽  
Author(s):  
Yoojung Kwon ◽  
Youngmi Kim ◽  
Hyun Jung ◽  
Dooil Jeoung
Keyword(s):  
Molecular Networks ◽  
Cancer Drug ◽  
Cancer Drugs ◽  
Angiogenic Potential ◽  
Histone Deacetylase 3 ◽  
Cancer Drug Resistance ◽  
Tumorigenic Potential ◽  
Anti Cancer ◽  
Cancer Testis

Histone modification is associated with resistance to anti-cancer drugs. Epigenetic modifications of histones can regulate resistance to anti-cancer drugs. It has been reported that histone deacetylase 3 (HDAC3) regulates responses to anti-cancer drugs, angiogenic potential, and tumorigenic potential of cancer cells in association with cancer-associated genes (CAGE), and in particular, a cancer/testis antigen gene. In this paper, we report the roles of microRNAs that regulate the expression of HDAC3 and CAGE involved in resistance to anti-cancer drugs and associated mechanisms. In this review, roles of HDAC3-miRNAs-CAGE molecular networks in resistance to anti-cancer drugs, and the relevance of HDAC3 as a target for developing anti-cancer drugs are discussed.

Abstract LB-123: Analyses of anti-cancer testis antigen antibodies in glioma patients treated with Delta-24 oncolytic adenovirus

2012 ◽  
Author(s):  
Juan Fueyo ◽  
Charles Conrad ◽  
Candelaria Gomez-Manzano ◽  
Amy Heimberger ◽  
Luis Vence ◽  
...  
Keyword(s):  
Oncolytic Adenovirus ◽  
Cancer Testis Antigen ◽  
Anti Cancer ◽  
Cancer Testis

scholarly journals Cancer/Testis Antigen CAGE Exerts Negative Regulation on p53 Expression through HDAC2 and Confers Resistance to Anti-cancer Drugs

2010 ◽  
Vol 285 (34) ◽  
pp. 25957-25968 ◽  
Author(s):  
Youngmi Kim ◽  
Hyunmi Park ◽  
Deokbum Park ◽  
Yun-Sil Lee ◽  
Jongseon Choe ◽  
...  
Keyword(s):  
Negative Regulation ◽  
Cancer Testis Antigen ◽  
Cancer Drugs ◽  
P53 Expression ◽  
Anti Cancer ◽  
Cancer Testis

scholarly journals Cancer testis antigen PRAME: An anti‐cancer target with immunomodulatory potential

2021 ◽  
Author(s):  
Adviti Naik ◽  
Remy Thomas ◽  
Ghaneya Al‐Khadairi ◽  
Rim Bacha ◽  
Wouter Hendrickx ◽  
...  
Keyword(s):  
Cancer Testis Antigen ◽  
Anti Cancer ◽  
Immunomodulatory Potential ◽  
Cancer Testis

Deactivation of anti-cancer drug letrozole to a carbinol metabolite by polymorphic cytochrome P450 2A6 in human liver microsomes

Xenobiotica ◽  
2009 ◽  
Vol 00 (00) ◽  
pp. 090901052053001-8
Author(s):  
K. Murai ◽  
H. Yamazaki ◽  
K. Nakagawa ◽  
R. Kawai ◽  
T. Kamataki
Keyword(s):  
Cytochrome P450 ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Cancer Drug ◽  
Anti Cancer ◽  
Cytochrome P450 2A6

Psychogenic Mass Syndrome in Anti-Cancer Drug Exposure

2010 ◽  
Author(s):  
N. Magnavita ◽  
I. lavicoli ◽  
V. Leso ◽  
A. Bergamaschi
Keyword(s):  
Drug Exposure ◽  
Cancer Drug ◽  
Anti Cancer
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