Development of a microfluidic device for cell concentration and blood cell-plasma separation

2015 ◽  
Vol 17 (6) ◽  
Author(s):  
M. Sneha Maria ◽  
B. S. Kumar ◽  
T. S. Chandra ◽  
A. K. Sen
Micromachines ◽  
2021 ◽  
Vol 12 (5) ◽  
pp. 487
Author(s):  
Hongyan Xu ◽  
Zhangying Wu ◽  
Jinan Deng ◽  
Jun Qiu ◽  
Ning Hu ◽  
...  

The development of a simple, portable, and cost-effective plasma separation platform for blood biochemical analysis is of great interest in clinical diagnostics. We represent a plasma separation microfluidic device using microspheres with different sizes as the separation barrier. This plasma separation device, with 18 capillary microchannels, can extract about 3 μL of plasma from a 50 μL blood sample in about 55 min. The effects of evaporation and the microsphere barrier on the plasma biochemical analysis results were studied. Correction factors were applied to compensate for these two effects. The feasibility of the device in plasma biochemical analysis was validated with clinical blood samples.


1969 ◽  
Vol 26 (4) ◽  
pp. 469-471 ◽  
Author(s):  
M De Raedt ◽  
N Portier ◽  
L Brasseur ◽  
K P Van de Woestijne

Nephron ◽  
1981 ◽  
Vol 27 (1) ◽  
pp. 35-39 ◽  
Author(s):  
Yoshimasa Orita ◽  
Akio Ando ◽  
Yoshihiro Tsubakihara ◽  
Hiroshi Mikami ◽  
Takeo Kikuchi ◽  
...  

2019 ◽  
Vol 209 ◽  
pp. 28-34 ◽  
Author(s):  
L. Spigarelli ◽  
V. Bertana ◽  
D. Marchisio ◽  
L. Scaltrito ◽  
S. Ferrero ◽  
...  

Biorheology ◽  
1983 ◽  
Vol 20 (1) ◽  
pp. 29-40 ◽  
Author(s):  
E.A. Schmalzer ◽  
R. Skalak ◽  
S. Usami ◽  
M. Vayo ◽  
S. Chien

2019 ◽  
Vol 91 (8) ◽  
pp. 5461-5468 ◽  
Author(s):  
Nan Xiang ◽  
Rui Zhang ◽  
Yu Han ◽  
Zhonghua Ni

1984 ◽  
Vol 13 (2) ◽  
pp. 167-173 ◽  
Author(s):  
Israel Hanin ◽  
Charles F. Reynolds ◽  
David J. Kupfer ◽  
Ursula Kopp ◽  
Lynn S. Taska ◽  
...  

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