Centrifugal Separation Device Based on Two-Layer Laminar Flow in Microchannels for High-Throughput and Continuous Blood Cell/Plasma Separation

2010 ◽  
Vol 49 (7) ◽  
pp. 077001 ◽  
Author(s):  
Taizo Kobayashi ◽  
Taisuke Funamoto ◽  
Makoto Hosaka ◽  
Satoshi Konishi
Keyword(s):  
Laminar Flow ◽  
Blood Cell ◽  
High Throughput ◽  
Centrifugal Separation ◽  
Separation Device ◽  
Plasma Separation ◽  
Cell Plasma

Blood Cell Separation Device Using Serially Connected Membrane Filters for Adapting to Blood Flow Properties

2009 ◽  
Vol 129 (11) ◽  
pp. 380-386 ◽  
Author(s):  
Taizo Kobayashi ◽  
Daiki Kato ◽  
Hiroyuki Koga ◽  
Kenichi Morimoto ◽  
Makoto Fukuda ◽  
...  
Keyword(s):  
Blood Flow ◽  
Blood Cell ◽  
Cell Separation ◽  
Flow Properties ◽  
Separation Device ◽  
Membrane Filters

scholarly journals Microsphere-Based Microfluidic Device for Plasma Separation and Potential Biochemistry Analysis Applications

Micromachines ◽  
2021 ◽  
Vol 12 (5) ◽  
pp. 487
Author(s):  
Hongyan Xu ◽  
Zhangying Wu ◽  
Jinan Deng ◽  
Jun Qiu ◽  
Ning Hu ◽  
...  
Keyword(s):  
Blood Sample ◽  
Microfluidic Device ◽  
Biochemical Analysis ◽  
Cost Effective ◽  
Clinical Diagnostics ◽  
Correction Factors ◽  
Separation Device ◽  
Blood Samples ◽  
Plasma Separation ◽  
Blood Biochemical

The development of a simple, portable, and cost-effective plasma separation platform for blood biochemical analysis is of great interest in clinical diagnostics. We represent a plasma separation microfluidic device using microspheres with different sizes as the separation barrier. This plasma separation device, with 18 capillary microchannels, can extract about 3 μL of plasma from a 50 μL blood sample in about 55 min. The effects of evaporation and the microsphere barrier on the plasma biochemical analysis results were studied. Correction factors were applied to compensate for these two effects. The feasibility of the device in plasma biochemical analysis was validated with clinical blood samples.

Fast blood plasma separation device for point-of-care applications

Talanta ◽  
2018 ◽  
Vol 183 ◽  
pp. 55-60 ◽  
Author(s):  
Pavol Ďurč ◽  
František Foret ◽  
Petr Kubáň
Keyword(s):  
Blood Plasma ◽  
Point Of Care ◽  
Separation Device ◽  
Plasma Separation ◽  
Blood Plasma Separation

High-throughput microsphiltration to assess red blood cell deformability and screen for malaria transmission–blocking drugs

2018 ◽  
Vol 13 (6) ◽  
pp. 1362-1376 ◽  
Author(s):  
Julien Duez ◽  
Mario Carucci ◽  
Irene Garcia-Barbazan ◽  
Matias Corral ◽  
Oscar Perez ◽  
...  
Keyword(s):  
Blood Cell ◽  
Malaria Transmission ◽  
High Throughput ◽  
Red Blood Cell ◽  
Cell Deformability ◽  
Transmission Blocking ◽  
Red Blood Cell Deformability

Microfluidic Pipette Tip for High-Purity and High-Throughput Blood Plasma Separation from Whole Blood

2017 ◽  
Vol 89 (3) ◽  
pp. 1439-1444 ◽  
Author(s):  
Byeongyeon Kim ◽  
Sein Oh ◽  
Dongwon You ◽  
Sungyoung Choi
Keyword(s):  
Blood Plasma ◽  
High Throughput ◽  
High Purity ◽  
Whole Blood ◽  
Plasma Separation ◽  
Pipette Tip ◽  
Blood Plasma Separation

Elevated red blood cell/plasma choline ratio in dimentia of the Alzheimer type: Clinical and polysomnographic correlates

1984 ◽  
Vol 13 (2) ◽  
pp. 167-173 ◽  
Author(s):  
Israel Hanin ◽  
Charles F. Reynolds ◽  
David J. Kupfer ◽  
Ursula Kopp ◽  
Lynn S. Taska ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Alzheimer Type ◽  
Cell Plasma
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