A Functional Neuroimaging Case Study of Meares–Irlen Syndrome/Visual Stress (MISViS)

2011 ◽  
Vol 25 (3) ◽  
pp. 293-307 ◽  
Author(s):  
Brea D. Chouinard ◽  
Crystal I. Zhou ◽  
Stanislau Hrybouski ◽  
Esther S. Kim ◽  
Jacqueline Cummine
Neurocase ◽  
2021 ◽  
Vol 27 (1) ◽  
pp. 97-105
Author(s):  
Sarah M. Schneck ◽  
Jillian L. Entrup ◽  
Melissa C. Duff ◽  
Stephen M. Wilson

2019 ◽  
Author(s):  
João Vitor Macedo Romera ◽  
Rafael Nobre Orsi ◽  
Rodrigo Filev Maia ◽  
Carlos Eduardo Thomaz

This work investigates reading patterns based on effects of the Meares-Irlen Syndrome (SMI), a visual-perception deficit that affects indirectly our cognitive system. The most common symptoms related to SMI in reading tasks are visual stress, sensation of moving letters and distortions in the text. These effects have been computationally simulated here and using eye-tracking information of a number of participants we have been able to linearly classify each effects with high accuracy.


2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Michael J. Gawrysiak ◽  
John P. Carvalho ◽  
Baxter P. Rogers ◽  
Christopher R. N. Nicholas ◽  
John H. Dougherty ◽  
...  

Functional neuroimaging is an innovative but at this stage underutilized method to assess the efficacy of psychotherapy for depression. Functional magnetic resonance imaging (fMRI) was used in this case study to examine changes in brain activity in a depressed breast cancer patient receiving an 8-session Behavioral Activation Treatment for Depression (BATD), based on the work of Hopko and Lejuez (2007). A music listening paradigm was used during fMRI brain scans to assess reward responsiveness at pre- and posttreatment. Following treatment, the patient exhibited attenuated depression and changes in blood oxygenation level dependence (BOLD) response in regions of the prefrontal cortex and the subgenual cingulate cortex. These preliminary findings outline a novel means to assess psychotherapy efficacy and suggest that BATD elicits functional brain changes in areas implicated in the pathophysiology of depression. Further research is necessary to explore neurobiological mechanisms of change in BATD, particularly the potential mediating effects of reward responsiveness and associated brain functioning.


Neurology ◽  
2020 ◽  
Vol 95 (15) ◽  
pp. e2109-e2118 ◽  
Author(s):  
Antonio Méndez-Guerrero ◽  
María Isabel Laespada-García ◽  
Adolfo Gómez-Grande ◽  
Mariano Ruiz-Ortiz ◽  
Víctor Antonio Blanco-Palmero ◽  
...  

ObjectiveTo report a case of a patient infected with severe acute respiratory syndrome coronavirus 2 (SARS–CoV-2) who acutely developed a hypokinetic-rigid syndrome.MethodsPatient data were obtained from medical records from the Hospital Universitario 12 de Octubre in Madrid, Spain. [123I]-ioflupane dopamine transporter (DaT) SPECT images were acquired 4 hours after a single dose of 185 MBq of 123I-FP-CIT. Quantitative analysis was performed with DaTQUANT software providing the specific binding ratio and z score values of the striatum.ResultsWe report a previously healthy 58-year-old man who developed hyposmia, generalized myoclonus, fluctuating and transient changes in level of consciousness, opsoclonus, and an asymmetric hypokinetic-rigid syndrome with ocular abnormalities after a severe SARS–CoV-2 infection. DaT-SPECT confirmed a bilateral decrease in presynaptic dopamine uptake asymmetrically involving both putamina. Significant improvement in the parkinsonian symptoms was observed without any specific treatment.ConclusionThis case study provides clinical and functional neuroimaging evidence to support that SARS–CoV-2 can gain access to the CNS, affecting midbrain structures and leading to neurologic signs and symptoms.


2014 ◽  
Vol 38 (01) ◽  
pp. 102-129
Author(s):  
ALBERTO MARTÍN ÁLVAREZ ◽  
EUDALD CORTINA ORERO

AbstractUsing interviews with former militants and previously unpublished documents, this article traces the genesis and internal dynamics of the Ejército Revolucionario del Pueblo (People's Revolutionary Army, ERP) in El Salvador during the early years of its existence (1970–6). This period was marked by the inability of the ERP to maintain internal coherence or any consensus on revolutionary strategy, which led to a series of splits and internal fights over control of the organisation. The evidence marshalled in this case study sheds new light on the origins of the armed Salvadorean Left and thus contributes to a wider understanding of the processes of formation and internal dynamics of armed left-wing groups that emerged from the 1960s onwards in Latin America.


2020 ◽  
Vol 43 ◽  
Author(s):  
Michael Lifshitz ◽  
T. M. Luhrmann

Abstract Culture shapes our basic sensory experience of the world. This is particularly striking in the study of religion and psychosis, where we and others have shown that cultural context determines both the structure and content of hallucination-like events. The cultural shaping of hallucinations may provide a rich case-study for linking cultural learning with emerging prediction-based models of perception.


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