scholarly journals Scan–rescan reproducibility of diastolic left ventricular kinetic energy, viscous energy loss and vorticity assessment using 4D flow MRI: analysis in healthy subjects

2018 ◽  
Vol 34 (6) ◽  
pp. 905-920 ◽  
Author(s):  
Vivian P. Kamphuis ◽  
Jos J. M. Westenberg ◽  
Roel L. F. van der Palen ◽  
Pieter J. van den Boogaard ◽  
Rob J. van der Geest ◽  
...  
Keyword(s):  
Kinetic Energy ◽  
Energy Loss ◽  
Healthy Subjects ◽  
Left Ventricular ◽  
4D Flow Mri ◽  
4D Flow ◽  
Flow Mri

Hemodynamic interplay of vorticity, viscous energy loss, and kinetic energy from 4D Flow MRI and link to cardiac function in healthy subjects and Fontan patients

2021 ◽  
Vol 320 (4) ◽  
pp. H1687-H1698
Author(s):  
Vivian P. Kamphuis ◽  
Arno A. W. Roest ◽  
Pieter J. van den Boogaard ◽  
Lucia J. M. Kroft ◽  
Hildo J. Lamb ◽  
...  
Keyword(s):  
Kinetic Energy ◽  
Energy Loss ◽  
Cardiovascular Magnetic Resonance Imaging ◽  
Healthy Subjects ◽  
Energy Levels ◽  
Resonance Imaging ◽  
4D Flow Mri ◽  
4D Flow ◽  
Flow Mri ◽  
Fontan Patients

Physiologic intraventricular hemodynamic interplay/coupling is present in the healthy left ventricle between vorticity versus viscous energy loss and kinetic energy from four-dimensional flow cardiovascular magnetic resonance imaging (4D Flow MRI). Conversely, Fontan patients present compensatory pathophysiologic hemodynamic coupling by an increase in intraventricular vorticity that positively correlates to viscous energy loss and kinetic energy levels in the presence of maintained normal stroke volume. Altered vorticity and energetics are found in the presence of normal ejection fraction in Fontan patients.

scholarly journals Unilateral branch pulmonary artery stenting in tetralogy of fallot improves ventricular function

2021 ◽  
Vol 22 (Supplement_2) ◽  
Author(s):  
MM Bissell ◽  
L Mills ◽  
DGW Cave ◽  
R Foley ◽  
JP Greenwood ◽  
...  
Keyword(s):  
Kinetic Energy ◽  
Ejection Fraction ◽  
Pulmonary Artery ◽  
Longitudinal Strain ◽  
Left Ventricular ◽  
Energy Curve ◽  
4D Flow Mri ◽  
4D Flow ◽  
Flow Mri

Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): NIHR Background Pulmonary artery stenosis (PAS) occurs commonly in patients with tetralogy of fallot (ToF). Cardiac function and especially left ventricular longitudinal strain has been identified as an important prognostic factor for long term survival in ToF. The clinical relevance of unilateral PAS to long-term bi-ventricular function is poorly understood. Purpose We sought to evaluate the effect of resolving unilateral pulmonary artery obstruction on right and left ventricular performance. Methods We prospectively included 40 patients with TOF between 2016 and 2020, 20 who underwent unilateral PAS stenting and as comparison 20 who underwent surgical pulmonary valve replacement (PVR). MRI data was acquired during routine clinical care before and around 6-12 months after the procedure. 4 PAS patients attended additional research scans acquiring ventricular 4D flow MRI data. 4D flow MRI data was compared to the average kinetic energy curve of 10 age-matched healthy volunteers. Results Of the 20 patients undergoing PAS, 2 also underwent percutaneous PVR and were excluded from the comparison analysis. All patients in the PAs group showed an improvement in branch PA flow differential post procedure. Patients undergoing PAS were younger than those undergoing PVR (median 12 vs 19 years, p < 0.001). Other baseline anatomical and functional parameters including right ventricular (RV) volume indexed to body surface are (RVEDV/BSA) were comparable (pre PAS median 151 [122,170] vs pre PVR 162 [140,191]; p = 0.217). While in the PVR group the right ventricular volumes reduced in both end-diastole and end-systole, in the PAS group RV function improved due to reduced end-systolic volume with largely stable end-diastolic volumes. Changes in the left ventricle (LV) were even more interesting. In the PVR group ejection fraction improved due to an increase in end-diastolic volume with no improvement in ventricular longitudinal strain. In contrast, in the PAS group LV ejection fraction improved by a reduction in end-systolic volume and the PAS group showed a small but significant improvement in LV longitudinal strain. In addition, ¾ patients undergoing 4D flow MRI assessment showed LV kinetic energy curve more similar to the healthy volunteer averaged  LV kinetic energy curve after PAS. The 4th patient already had a near normal LV kinetic energy curve prior to PAS. Conclusion Unilateral PAS does not alter RV end-diastolic volumes but improves RV function. LV ejection fraction improvement is similar to that seen after PVR, but importantly PAS also improved LV longitudinal strain. This suggests that PAS might positively influence long term morbidity and mortality risk in ToF patients, but a larger multi-centre long term follow-up study is needed to confirm this.

scholarly journals Quantification of left ventricular kinetic energy using 4D flow MRI

2010 ◽  
Vol 12 (S1) ◽  
Author(s):  
Thomas A Wåxnäs ◽  
Einar Heiberg ◽  
Johannes Togert ◽  
Marten Larsson ◽  
Hakan Arheden ◽  
...  
Keyword(s):  
Kinetic Energy ◽  
Left Ventricular ◽  
4D Flow Mri ◽  
4D Flow ◽  
Flow Mri

scholarly journals Altered Diastolic Flow Patterns and Kinetic Energy in Subtle Left Ventricular Remodeling and Dysfunction Detected by 4D Flow MRI

PLoS ONE ◽  
2016 ◽  
Vol 11 (8) ◽  
pp. e0161391 ◽  
Author(s):  
Emil Svalbring ◽  
Alexandru Fredriksson ◽  
Jonatan Eriksson ◽  
Petter Dyverfeldt ◽  
Tino Ebbers ◽  
...  
Keyword(s):  
Kinetic Energy ◽  
Ventricular Remodeling ◽  
Left Ventricular Remodeling ◽  
Flow Patterns ◽  
Left Ventricular ◽  
4D Flow Mri ◽  
4D Flow ◽  
Diastolic Flow ◽  
Flow Mri

scholarly journals Segmental assessment of blood flow efficiency in the total cavopulmonary connection using 4D flow MRI: vortical flow is associated with increased viscous energy loss

2021 ◽  
Author(s):  
Friso M Rijnberg ◽  
Joe F Juffermans ◽  
Mark G Hazekamp ◽  
Willem A Helbing ◽  
Hildo J Lamb ◽  
...  
Keyword(s):  
Kinetic Energy ◽  
Energy Loss ◽  
Loss Rate ◽  
Superior Vena ◽  
Vena Cava ◽  
Vortical Flow ◽  
4D Flow Mri ◽  
4D Flow ◽  
Energy Loss Rate ◽  
Flow Mri

Abstract Objectives To study flow-related energetics in multiple anatomical segments of the total cavopulmonary connection (TCPC) in Fontan patients from 4D flow MRI, and to study the relationship between adverse flow patterns and segment-specific energetics. Methods Twenty-six extracardiac Fontan patients underwent 4D flow MRI of the TCPC. A segmentation of the TCPC was automatically divided into 5 anatomical segments (conduit, superior vena cava, right/left pulmonary artery (PA) and the Fontan confluence). The presence of vortical flow in the PAs or Fontan confluence was qualitatively scored. Kinetic energy, viscous energy loss and vorticity were calculated from the 4D flow MRI velocity field and normalized for segment length and/or inflow. Energetics were compared between segments and the relationship between vortical flow and segment cross-sectional area (CSA) with segment-specific energetics was determined. Results Vortical flow in the LPA (n = 6) and Fontan confluence (n = 12) were associated with significantly higher vorticity (p = 0.001 and p = 0.015, respectively) and viscous energy loss rate (p = 0.046 and p = 0.04, respectively) compared to patients without vortical flow. The LPA and conduit segments showed the highest kinetic energy and viscous energy loss rate, while most favorable energetics were observed in the superior vena cava. Conduit CSA inversely correlated with kinetic energy (r= -0.614, p = 0.019) and viscous energy loss rate (r= -0.652, p = 0.011). Conclusions Vortical flow in the Fontan confluence and LPA associated with significantly increased viscous energy loss rate. 4D flow MRI derived energetics may be used as a screening tool for direct, MRI-based assessment of flow efficiency in the TCPC.

scholarly journals Four-Dimensional Flow MRI of Abdominal Veins: A Systematic Review

Diagnostics ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 767
Author(s):  
Simon O. Haarbye ◽  
Michael B. Nielsen ◽  
Adam E. Hansen ◽  
Carsten A. Lauridsen
Keyword(s):  
Systematic Review ◽  
Blood Flow ◽  
Portal Hypertension ◽  
Healthy Subjects ◽  
Visual Quality ◽  
Sampling Strategies ◽  
4D Flow Mri ◽  
4D Flow ◽  
Dimensional Flow ◽  
Flow Mri

The aim of this systematic review is to provide an overview of the use of Four-Dimensional Magnetic Resonance Imaging of vector blood flow (4D Flow MRI) in the abdominal veins. This study was composed according to the PRISMA guidelines 2009. The literature search was conducted in MEDLINE, Cochrane Library, EMBASE, and Web of Science. Quality assessment of the included studies was performed using the QUADAS-2 tool. The initial search yielded 781 studies and 21 studies were included. All studies successfully applied 4D Flow MRI in abdominal veins. Four-Dimensional Flow MRI was capable of discerning between healthy subjects and patients with cirrhosis and/or portal hypertension. The visual quality and inter-observer agreement of 4D Flow MRI were rated as excellent and good to excellent, respectively, and the studies utilized several different MRI data sampling strategies. By applying spiral sampling with compressed sensing to 4D Flow MRI, the blood flow of several abdominal veins could be imaged simultaneously in 18–25 s, without a significant loss of visual quality. Four-Dimensional Flow MRI might be a useful alternative to Doppler sonography for the diagnosis of cirrhosis and portal hypertension. Further clinical studies need to establish consensus regarding MRI sampling strategies in patients and healthy subjects.

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