scholarly journals Will biomarker-based diagnosis of Alzheimer’s disease maximize scientific progress? Evaluating proposed diagnostic criteria

2018 ◽  
Vol 33 (7) ◽  
pp. 607-612 ◽  
Author(s):  
Medellena Maria Glymour ◽  
Adam Mark Brickman ◽  
Mika Kivimaki ◽  
Elizabeth Rose Mayeda ◽  
Geneviève Chêne ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Diagnostic Criteria ◽  
Scientific Progress

scholarly journals Alzheimer's Disease–Related Dementias Summit 2016: National research priorities

Neurology ◽  
2017 ◽  
Vol 89 (23) ◽  
pp. 2381-2391 ◽  
Author(s):  
Roderick A. Corriveau ◽  
Walter J. Koroshetz ◽  
Jordan T. Gladman ◽  
Sophia Jeon ◽  
Debra Babcock ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Alzheimer Disease ◽  
Scientific Progress ◽  
Research Priorities ◽  
Lewy Body Dementia ◽  
National Plan ◽  
Relevant Research ◽  
Challenges And Opportunities ◽  
Dementia Research

Goal 1 of the National Plan to Address Alzheimer’s Disease is to prevent and effectively treat Alzheimer disease and Alzheimer disease–related dementias by 2025. To help inform the research agenda toward achieving this goal, the NIH hosts periodic summits that set and refine relevant research priorities for the subsequent 5 to 10 years. This proceedings article summarizes the 2016 Alzheimer's Disease–Related Dementias Summit, including discussion of scientific progress, challenges, and opportunities in major areas of dementia research, including mixed-etiology dementias, Lewy body dementia, frontotemporal degeneration, vascular contributions to cognitive impairment and dementia, dementia disparities, and dementia nomenclature.

Preclinical Alzheimer's disease

2014 ◽  
Vol 24 (2) ◽  
pp. 117-121
Author(s):  
P Gil-Gregorio ◽  
R Yubero-Pancorbo
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Decline ◽  
Diagnostic Criteria ◽  
Stage I ◽  
Disease Stage ◽  
Synaptic Dysfunction ◽  
Preclinical Alzheimer’S Disease ◽  
Cerebral Amyloidosis ◽  
Three Stages

SummaryRecently, diagnostic criteria for preclinical Alzheimer's disease have been proposed. These describe and define three stages of disease. Stage I is focused on asymptomatic cerebral amyloidosis. Stage II includes evidence of synaptic dysfunction and/or early degeneration. Finally, stage III of the disease is characterized by the beginning of cognitive decline.

scholarly journals Research diagnostic criteria for Alzheimer’s disease: Findings from the multinational LipiDiDiet Trial

2020 ◽  
Vol 16 (S5) ◽  
Author(s):  
Anna Rosenberg ◽  
Alina Solomon ◽  
Hilkka Soininen ◽  
Pieter Jelle Visser ◽  
Kaj Blennow ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Diagnostic Criteria ◽  
Research Diagnostic Criteria

Peripheral Markers and Diagnostic Criteria in Alzheimer's Disease: Critical Evaluations

1994 ◽  
Vol 5 (3) ◽  
Author(s):  
Eugenia S. de Lustig ◽  
Silvia Kohan ◽  
Arturo L. Famulari ◽  
Raul O. Dominguez ◽  
Jorge A. Serra
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Diagnostic Criteria ◽  
Peripheral Markers

A Case-Control Study of Alzheimer's Disease and Aluminium Occupation

1996 ◽  
Vol 168 (2) ◽  
pp. 244-249 ◽  
Author(s):  
Emad Salib ◽  
Valerie Hillier
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Diagnostic Criteria ◽  
Odds Ratio ◽  
Direct Contact ◽  
Case Control Study ◽  
Working Life ◽  
Case Control ◽  
Occupational History ◽  
Control Study

BackgroundWe examined clinically diagnosed Alzheimer's disease patients and controls, and collected information from informants, to examine the association between Alzheimer's disease and aluminium occupation.MethodAn unmatched case-control study comparing 198 cases of Alzheimer's disease (ADRDA–NINCDS diagnostic criteria), to selected controls (164 other dementias and 176 non-dementing group) in respect of their occupational history. The subjects included all patients referred to and seen by the first author during a 2 year study period.ResultsTwenty-two of 198 patients with Alzheimer's disease (11.1 %) reported having an aluminium occupation at some stage in their working life compared with 39 of 340 controls (11.5%), odds ratio 0.98, 95% CI 0.53–1.75, P > 0.05. Aluminium workers reported to have worked in direct contact with aluminium dust and fumes did not appear to be at any greater risk than other workers who were employed at the same factory, odds ratio 1.19, 95% CI, 0.64–4.18, P > 0.05.ConclusionThere is no evidence to support an association between having previously worked in an aluminium factory and the risk of Alzheimer's disease later in life.

Sign in / Sign up

Export Citation Format

Share Document