Associating physiological functions with genomic variability in hibernating bats

2021 ◽  
Author(s):  
Markéta Harazim ◽  
Lubomír Piálek ◽  
Jiri Pikula ◽  
Veronika Seidlová ◽  
Jan Zukal ◽  
...  
Keyword(s):  
Genomic Variability ◽  
Physiological Functions

Kruppel-Like Factor 4: From Physiological Functions to Tumor Therapy

2016 ◽  
Vol 7 (1-2) ◽  
pp. 153-158
Author(s):  
Ruocong Zhao ◽  
Yunxin Lai ◽  
Peng Li
Keyword(s):  
Tumor Therapy ◽  
Physiological Functions

Physiological Functions of NO-Sensitive Guanylyl Cyclase Isoforms

2016 ◽  
Vol 23 (24) ◽  
pp. 2653-2665 ◽  
Author(s):  
Doris Koesling ◽  
Evanthia Mergia ◽  
Michael Russwurm
Keyword(s):  
Guanylyl Cyclase ◽  
Physiological Functions

Isoleucine Plays an Important Role for Maintaining Immune Function

2019 ◽  
Vol 20 (7) ◽  
pp. 644-651 ◽  
Author(s):  
Changsong Gu ◽  
Xiangbing Mao ◽  
Daiwen Chen ◽  
Bing Yu ◽  
Qing Yang
Keyword(s):  
Amino Acids ◽  
Acid Metabolism ◽  
Branched Chain Amino Acids ◽  
Whole Body ◽  
Immune Functions ◽  
Host Defense Peptides ◽  
Innate And Adaptive Immunity ◽  
Physiological Functions ◽  
Branched Chain ◽  
The Relationship

Branched chain amino acids are the essential nutrients for humans and many animals. As functional amino acids, they play important roles in physiological functions, including immune functions. Isoleucine, as one of the branched chain amino acids, is also critical in physiological functions of the whole body, such as growth, immunity, protein metabolism, fatty acid metabolism and glucose transportation. Isoleucine can improve the immune system, including immune organs, cells and reactive substances. Recent studies have also shown that isoleucine may induce the expression of host defense peptides (i.e., β-defensins) that can regulate host innate and adaptive immunity. In addition, isoleucine administration can restore the effect of some pathogens on the health of humans and animals via increasing the expression of β-defensins. Therefore, the present review will emphatically discuss the effect of isoleucine on immunity while summarizing the relationship between branched chain amino acids and immune functions.

Genomic Variability of Pathogenicity Islands in Nontoxigenic Strains of Vibrio cholerae O1 Biotype El Tor

2020 ◽  
Vol 56 (9) ◽  
pp. 1055-1069
Author(s):  
N. I. Smirnova ◽  
A. A. Kritsky ◽  
J. V. Alkhova ◽  
E. Yu. Agafonova ◽  
E. Yu. Shchelkanova ◽  
...  
Keyword(s):  
Vibrio Cholerae ◽  
Pathogenicity Islands ◽  
Genomic Variability ◽  
Vibrio Cholerae O1 ◽  
El Tor
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