A unified framework for domain independent online speaker indexing in eigen-voice space using an index tree of reference models

2013 ◽  
Vol 16 (4) ◽  
pp. 381-401
Author(s):  
M. H. Moattar ◽  
M. M. Homayounpour
Keyword(s):  
Unified Framework ◽  
Reference Models ◽  
Speaker Indexing ◽  
Index Tree ◽  
Domain Independent

scholarly journals The Communicative Multiagent Team Decision Problem: Analyzing Teamwork Theories and Models

2002 ◽  
Vol 16 ◽  
pp. 389-423 ◽  
Author(s):  
D. V. Pynadath ◽  
M. Tambe
Keyword(s):  
Computational Complexity ◽  
Decision Problem ◽  
Unified Framework ◽  
Team Coordination ◽  
Team Theory ◽  
Coordination Strategies ◽  
Markov Decision ◽  
Team Decision ◽  
Partially Observable ◽  
Domain Independent

Despite the significant progress in multiagent teamwork, existing research does not address the optimality of its prescriptions nor the complexity of the teamwork problem. Without a characterization of the optimality-complexity tradeoffs, it is impossible to determine whether the assumptions and approximations made by a particular theory gain enough efficiency to justify the losses in overall performance. To provide a tool for use by multiagent researchers in evaluating this tradeoff, we present a unified framework, the COMmunicative Multiagent Team Decision Problem (COM-MTDP). The COM-MTDP model combines and extends existing multiagent theories, such as decentralized partially observable Markov decision processes and economic team theory. In addition to their generality of representation, COM-MTDPs also support the analysis of both the optimality of team performance and the computational complexity of the agents' decision problem. In analyzing complexity, we present a breakdown of the computational complexity of constructing optimal teams under various classes of problem domains, along the dimensions of observability and communication cost. In analyzing optimality, we exploit the COM-MTDP's ability to encode existing teamwork theories and models to encode two instantiations of joint intentions theory taken from the literature. Furthermore, the COM-MTDP model provides a basis for the development of novel team coordination algorithms. We derive a domain-independent criterion for optimal communication and provide a comparative analysis of the two joint intentions instantiations with respect to this optimal policy. We have implemented a reusable, domain-independent software package based on COM-MTDPs to analyze teamwork coordination strategies, and we demonstrate its use by encoding and evaluating the two joint intentions strategies within an example domain.

A unified framework for automated person re-indentification

2020 ◽  
Vol 71 (7) ◽  
pp. 868-880
Author(s):  
Nguyen Hong-Quan ◽  
Nguyen Thuy-Binh ◽  
Tran Duc-Long ◽  
Le Thi-Lan
Keyword(s):  
Deep Learning ◽  
Video Analysis ◽  
Camera Network ◽  
Unified Framework ◽  
Person Detection ◽  
Practical Applications ◽  
Detection And Tracking ◽  
Analysis System ◽  
Bounding Boxes

Along with the strong development of camera networks, a video analysis system has been become more and more popular and has been applied in various practical applications. In this paper, we focus on person re-identification (person ReID) task that is a crucial step of video analysis systems. The purpose of person ReID is to associate multiple images of a given person when moving in a non-overlapping camera network. Many efforts have been made to person ReID. However, most of studies on person ReID only deal with well-alignment bounding boxes which are detected manually and considered as the perfect inputs for person ReID. In fact, when building a fully automated person ReID system the quality of the two previous steps that are person detection and tracking may have a strong effect on the person ReID performance. The contribution of this paper are two-folds. First, a unified framework for person ReID based on deep learning models is proposed. In this framework, the coupling of a deep neural network for person detection and a deep-learning-based tracking method is used. Besides, features extracted from an improved ResNet architecture are proposed for person representation to achieve a higher ReID accuracy. Second, our self-built dataset is introduced and employed for evaluation of all three steps in the fully automated person ReID framework.

AutoLinker: Automatic Fragment Linking with Deep Conditional Transformer Neural Networks

2020 ◽  
Author(s):  
Yuyao Yang ◽  
Shuangjia Zheng ◽  
Shimin Su ◽  
Jun Xu ◽  
Hongming Chen
Keyword(s):  
Neural Networks ◽  
Drug Discovery ◽  
Drug Design ◽  
State Of The Art ◽  
The State ◽  
Generative Model ◽  
Lead Optimization ◽  
Scaffold Hopping ◽  
Reference Models ◽  
Lead Generation

Fragment based drug design represents a promising drug discovery paradigm complimentary to the traditional HTS based lead generation strategy. How to link fragment structures to increase compound affinity is remaining a challenge task in this paradigm. Hereby a novel deep generative model (AutoLinker) for linking fragments is developed with the potential for applying in the fragment-based lead generation scenario. The state-of-the-art transformer architecture was employed to learn the linker grammar and generate novel linker. Our results show that, given starting fragments and user customized linker constraints, our AutoLinker model can design abundant drug-like molecules fulfilling these constraints and its performance was superior to other reference models. Moreover, several examples were showcased that AutoLinker can be useful tools for carrying out drug design tasks such as fragment linking, lead optimization and scaffold hopping.

A Unified Model for Photophysical and Electro-Optical Properties of Green Fluorescent Proteins

2019 ◽  
Author(s):  
Chi-Yun Lin ◽  
Matthew Romei ◽  
Luke Oltrogge ◽  
Irimpan Mathews ◽  
Steven Boxer
Keyword(s):  
Driving Force ◽  
Fluorescent Protein ◽  
Charge Transfer Band ◽  
Photophysical Properties ◽  
Polymethine Dyes ◽  
Emission Rates ◽  
Unified Framework ◽  
Underlying Factor ◽  
Green Fluorescent ◽  
Protein Environment

Green fluorescent protein (GFPs) have become indispensable imaging and optogenetic tools. Their absorption and emission properties can be optimized for specific applications. Currently, no unified framework exists to comprehensively describe these photophysical properties, namely the absorption maxima, emission maxima, Stokes shifts, vibronic progressions, extinction coefficients, Stark tuning rates, and spontaneous emission rates, especially one that includes the effects of the protein environment. In this work, we study the correlations among these properties from systematically tuned GFP environmental mutants and chromophore variants. Correlation plots reveal monotonic trends, suggesting all these properties are governed by one underlying factor dependent on the chromophore's environment. By treating the anionic GFP chromophore as a mixed-valence compound existing as a superposition of two resonance forms, we argue that this underlying factor is defined as the difference in energy between the two forms, or the driving force, which is tuned by the environment. We then introduce a Marcus-Hush model with the bond length alternation vibrational mode, treating the GFP absorption band as an intervalence charge transfer band. This model explains all the observed strong correlations among photophysical properties; related subtopics are extensively discussed in Supporting Information. Finally, we demonstrate the model's predictive power by utilizing the additivity of the driving force. The model described here elucidates the role of the protein environment in modulating photophysical properties of the chromophore, providing insights and limitations for designing new GFPs with desired phenotypes. We argue this model should also be generally applicable to both biological and non-biological polymethine dyes.<br>

Sign in / Sign up

Export Citation Format

Share Document