Yeast RNA extract suppresses human osteoclast resorption in vitro

2017 ◽  
Vol 25 (5) ◽  
pp. 571-576
Author(s):  
Melissa D. Cantley ◽  
K. D. Rainsford ◽  
David R. Haynes
Keyword(s):  
Human Osteoclast ◽  
Osteoclast Resorption ◽  
Rna Extract

scholarly journals Potent and selective cathepsin L inhibitors do not inhibit human osteoclast resorption in vitro.

2003 ◽  
Vol 278 (34) ◽  
pp. 32484
Author(s):  
Ian E. James ◽  
Robert W. Marquis ◽  
Simon M. Blake ◽  
Shing Mei Hwang ◽  
Catherine J. Gress ◽  
...  
Keyword(s):  
Cathepsin L ◽  
Human Osteoclast ◽  
Osteoclast Resorption

The effect of exogenous RNA extract on chick embryo fibroblasts in vitro

Development ◽  
1970 ◽  
Vol 23 (2) ◽  
pp. 509-517
Author(s):  
A. Sann ◽  
D. Sharp ◽  
J. McKenzie
Keyword(s):  
Cell Differentiation ◽  
Chick Embryo ◽  
Morphological Changes ◽  
Bacterial Cells ◽  
Baby Hamster Kidney ◽  
Exogenous Rna ◽  
Embryo Fibroblasts ◽  
Stimulation Of ◽  
Rna Extract

It is extremely difficult, if not impossible, to reconcile the conflicting claims of those who have treated different cells and tissues with exogenous RNA. Some authors (e.g. Niu, Cordova & Niu, 1961; Niu, Cordova & Radbill, 1962) maintain that RNA extracts alter the course of cell differentiation to conform in morphological terms to the source of the RNA; in the same vein, Amos, Askonas & Soeiro (1964) have shown that, under certain conditions, RNA from mouse and bacterial cells can stimulate chick embryo fibroblasts to synthesize protein related antigenically to the origin of the RNA. Shepley, Ambrose & Kirby (1965), however, obtained stimulation of growth with permanent morphological changes in baby hamster kidney fibroblasts by the addition of RNA from a variety of sources.

Giant Cell Tumor of Bone: A Model for the in Vitro Human Osteoclast Characterization

1989 ◽  
Vol 75 (4) ◽  
pp. 389-395 ◽  
Author(s):  
Mario Campanacci ◽  
Gian Paolo Bagnara ◽  
Massimo Serra ◽  
Marco Giovannini ◽  
Paolo Tornasi ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Giant Cells ◽  
Cell Tumor ◽  
Cell Populations ◽  
In Vitro Growth ◽  
Human Osteoclast ◽  
High Doses

The in vitro growth pattern of cells obtained from bioptic material of ten patients with giant cell tumor of bone (GCT) was investigated. Cytochemical reactions and monoclonal antibodies raised against macrophage markers were tested on the two histologically identifiable GCT cell populations. Only monoclonal antibody EBM/11 stained both mononuclear and giant cells. EBM/11 positivity and resistance of acid phosphatase to high doses of tartrate strongly suggest that both mononuclear and giant cells belong to the same lineage.

scholarly journals Cannabinoids and bone: endocannabinoids modulate human osteoclast function in vitro

2012 ◽  
Vol 165 (8) ◽  
pp. 2584-2597 ◽  
Author(s):  
LS Whyte ◽  
L Ford ◽  
SA Ridge ◽  
GA Cameron ◽  
MJ Rogers ◽  
...  
Keyword(s):  
Human Osteoclast ◽  
Osteoclast Function

Induction in vitro of Antibodies to Phage T2: Antigens in the RNA Extract Employed

Science ◽  
1965 ◽  
Vol 149 (3688) ◽  
pp. 1106-1107 ◽  
Author(s):  
H. P. Friedman ◽  
A. B. Stavitsky ◽  
J. M. Solomon
Keyword(s):  
Rna Extract

BISPHOSPHONATES AFFECT HUMAN OSTEOCLAST DEVELOPMENT IN VITRO

Bone ◽  
2010 ◽  
Vol 46 ◽  
pp. S63-S64 ◽  
Author(s):  
Guillaume Mabilleau ◽  
Aaron Kwaasi ◽  
Afsie Sabokbar ◽  
Maria Tsoumpra ◽  
Frank Ebetino ◽  
...  
Keyword(s):  
Human Osteoclast ◽  
Development In Vitro

Human Osteoclast Formation and Activity In Vitro: Effects of Alendronate

1998 ◽  
Vol 13 (11) ◽  
pp. 1721-1729 ◽  
Author(s):  
V. Breuil ◽  
F. Cosman ◽  
L. Stein ◽  
W. Horbert ◽  
J. Nieves ◽  
...  
Keyword(s):  
Osteoclast Formation ◽  
Human Osteoclast ◽  
In Vitro Effects

Adenoviral down-regulation of osteopontin inhibits human osteoclast differentiation in vitro

2004 ◽  
Vol 93 (5) ◽  
pp. 896-903 ◽  
Author(s):  
Cathy J. Aitken ◽  
Jason M. Hodge ◽  
Geoffrey C. Nicholson
Keyword(s):  
Osteoclast Differentiation ◽  
Down Regulation ◽  
Human Osteoclast
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