scholarly journals Comparison of Perinatal Risk Factors Associated with Autism Spectrum Disorder (ASD), Intellectual Disability (ID), and Co-occurring ASD and ID

2015 ◽  
Vol 45 (8) ◽  
pp. 2361-2372 ◽  
Author(s):  
Laura A. Schieve ◽  
Heather B. Clayton ◽  
Maureen S. Durkin ◽  
Martha S. Wingate ◽  
Carolyn Drews-Botsch
Keyword(s):  
Risk Factors ◽  
Autism Spectrum Disorder ◽  
Intellectual Disability ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Perinatal Risk Factors ◽  
Perinatal Risk ◽  
Factors Associated

Association of Perinatal Risk Factors with Autism Spectrum Disorder

2017 ◽  
Vol 34 (03) ◽  
pp. 295-304 ◽  
Author(s):  
Michael Fassett ◽  
Morgan Peltier ◽  
Deborah Wing ◽  
Anny Xiang ◽  
Vicki Chiu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Autism Spectrum Disorder ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Perinatal Risk Factors ◽  
Perinatal Risk

A STUDY OF DEMOGRAPHIC AND RISK FACTORS OF CHILDREN WITH AUTISM SPECTRUM DISORDER

2021 ◽  
pp. 7-9
Author(s):  
Bobby Hmar ◽  
Suresh Chakravorty ◽  
Ammu Anil ◽  
Ripunjay Khatoniar
Keyword(s):  
Risk Factors ◽  
Autism Spectrum Disorder ◽  
Birth Order ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Perinatal Risk Factors ◽  
Perinatal Risk ◽  
Lower Segment Caesarean Section ◽  
Co Morbidity ◽  
History Of

Background of the study: Various risk factors have been reported in the development of Autism spectrum Disorder. The aim of our study is to explore the demographic and perinatal risk factors implicated in the development of ASD. A retrospective study was conducted with data of 49 children with ASD and found that total 71.3% of children were male 73.5% were in rst birth order. Out of 49 children 53.1% had history of Lower Segment Caesarean Section (LSCS). Indication of LSCS due to various obstetric or perinatal risk factors were reported in 17 cases. Three children had history of low birth weight with history of admission into Neonatal ICU. The study also explore the various co morbidity and found that ADHD (20.4%) was most common comorbidity followed by Mental retardation(18.4%), ADHD and MR(12.2%), seizure disorder and MR (8.2 %). This study found that male gender, rst birth order and perinatal risk factors are implicated in the development of Autism spectrum Disorder and majority of them have one or more another neuro developmental disorder as a comorbidity.

scholarly journals Prenatal and Perinatal Factors Associated with Pediatric Autism Spectrum Disorder in East China

2021 ◽  
Author(s):  
Yu Li ◽  
Lu Han ◽  
Ning Ding ◽  
Ziyi Zhang ◽  
Yuan Lin ◽  
...  
Keyword(s):  
Risk Factors ◽  
Autism Spectrum Disorder ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Typical Development ◽  
Perinatal Factors ◽  
Perinatal Risk Factors ◽  
Perinatal Risk ◽  
Prenatal Factors ◽  
History Of

Abstract Background Autism spectrum disorder (ASD) is a complex neurodevelopmental condition characterized by persistent challenges in social communication and interaction and restricted/repetitive patterns of behavior, interests or activities. An increasing number of studies have revealed that environmental exposure is a potential risk factor for ASD. The relationship between prenatal and perinatal risk factors and ASD has rarely been studied in large samples in China. Therefore, in this study, we compared children with ASD with typical developing (TD) children to assess the ASD-associated prenatal and perinatal risk factors and provide effective information for ASD prevention. Methods A case-control study of 709 children with autism spectrum disorder (ASD) and 709 gender-matched children with typical development was conducted to investigate the prenatal and perinatal risk factors of children with ASD compared with children with typical development ( TD). Through a self-developed general information questionnaire, the basic information (name, age, gender), prenatal factors (parents’ age at the child’s birth, parents’ education levels, use of assisted reproductive technology, history of miscarriage, gestational diabetes mellitus, gestational hypertension), and perinatal factors (delivery mode, full-term birth, parity, birth weight) of the children in the two groups were examined. Results The prenatal and perinatal factors of the groups were submitted to univariate analysis, the parent’s age at childbirth, education level, history of miscarriage, use of ART, pregnancy-induced hypertension, and GDM differed significantly between the two groups (P<0.05), and that among perinatal factors, infant parity and maturity also differed significantly between the two groups (P<0.05). These statistically significant factors were included in a binary logistic regression model. The results showed that the prenatal factors of young maternal age at the child’s birth (≤24 years vs 25-29 years, OR=2.408,95%CI:1.335~4.345), old paternal age at the childbirth(≥45years vs≤24years, OR=4.744, 95%CI:1.281~17.570 ), pregnancy induced hypertension (OR=6.178, 95%CI:2.311~16.517) and GDM(OR=0.220,95%CI:0.149~0.324), the perinatal factors of preterm birth(OR=4.434, 95%CI:2.872~6.846) and non-firstborn child(OR=1.387, 95%CI:1.029~1.869) are likely risk factors for ASD. Conclusion We show that some prenatal and perinatal factors are associated with a high prevalence of ASD in children.

ASSOCIATION OF PERINATAL RISK FACTORS WITH AUTISM SPECTRUM DISORDER: A RETROSPECTIVE STUDY AT TERTIARY CARE CENTRE, MUMBAI

2021 ◽  
pp. 78-80
Author(s):  
Kondekar Alpana S ◽  
Sawant Vishal ◽  
Pendyala Chaitanya
Keyword(s):  
Risk Factors ◽  
Autism Spectrum Disorder ◽  
Risk Factor ◽  
Retrospective Study ◽  
Tertiary Care ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Perinatal Risk Factors ◽  
Perinatal Risk ◽  
Perinatal Risk Factor

Background: Autism spectrum disorder (ASD) is a complex neurodevelopmental condition, which is characterized by cognitive, behavioral, and social dysfunction. Their onset occurs in early childhood and during this period, there are various factors associated with autism risk. Hence,the present study was undertaken to determine the prevalence of various perinatal risk factors and its association with ASD in children. Methods: This was a retrospective study, included 200 cases of ASD over 5 years registered in pediatric neurodevelopment clinic at TN Medical College and BYL Nair Hospital, Mumbai. Study population divided in two groups- cases of ASD with perinatal risk factor and cases of ASD without perinatal risk factor. The prevalence of various perinatal risk factors in children with different grades of ASD calculated. Results: Based on ISAA score 149(74.5%) cases had mild autism and 51(25.5%) cases had moderate autism. The prevalence of various perinatal risk factors in children with different grades of ASD was found to be 79.5%(159/200). Pregnancy induced hypertension, bad obstetric history in mother were signicant risk factor for ASD. Lower segment caesarian section as mode of delivery was risk factor found to be associated more with mild form of autism, but statistically signicant association was found with vacuum delivery. We observed prematurity, low birth weight (LBW) and neonatal seizures as signicant risk factor, which may have contribution towards pathogenesis of ASD. Conclusion: The awareness between pediatrician and obstetrician about association of perinatal risk factors and ASD will denitely add to prevention and timely intervention of high risk patients.

Rate and Risk Factors Associated with Autism Spectrum Disorder in Congenital Diaphragmatic Hernia

2018 ◽  
Vol 48 (6) ◽  
pp. 2112-2121 ◽  
Author(s):  
Enrico Danzer ◽  
Casey Hoffman ◽  
Jo Ann D’Agostino ◽  
Judith S. Miller ◽  
Lindsay N. Waqar ◽  
...  
Keyword(s):  
Risk Factors ◽  
Autism Spectrum Disorder ◽  
Congenital Diaphragmatic Hernia ◽  
Diaphragmatic Hernia ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Factors Associated

scholarly journals Risk Factors Associated With Language in Autism Spectrum Disorder: Clues to Underlying Mechanisms

2016 ◽  
Vol 59 (1) ◽  
pp. 143-154 ◽  
Author(s):  
Helen Tager-Flusberg
Keyword(s):  
Risk Factors ◽  
Autism Spectrum Disorder ◽  
Language Impairment ◽  
Specific Language Impairment ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Risk Markers ◽  
Specific Language ◽  
Factors Associated ◽  
Wide Range

Purpose Identifying risk factors associated with neurodevelopmental disorders is an important line of research, as it will lead to earlier identification of children who could benefit from interventions that support optimal developmental outcomes. The primary goal of this review was to summarize research on risk factors associated with autism spectrum disorder (ASD). Method The review focused on studies of infants who have older siblings with ASD, with particular emphasis on risk factors associated with language impairment that affects the majority of children with ASD. Findings from this body of work were compared to the literature on specific language impairment. Results A wide range of risk factors has been found for ASD, including demographic (e.g., male, family history), behavioral (e.g., gesture, motor) and neural risk markers (e.g., atypical lateralization for speech and reduced functional connectivity). Environmental factors, such as caregiver interaction, have not been found to predict language outcomes. Many of the risk markers for ASD are also found in studies of risk for specific language impairment, including demographic, behavioral, and neural factors. Conclusions There are significant gaps in the literature and limitations in the current research that preclude direct cross-syndrome comparisons. Future research directions are outlined that could address these limitations.

Autism and Suicide

2017 ◽  
Author(s):  
Oren Shtayermman
Keyword(s):  
Risk Factors ◽  
Autism Spectrum Disorder ◽  
General Population ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Research Practice ◽  
Statistical Manual ◽  
Factors Associated ◽  
Dsm 5 ◽  
Methodological Challenges

This article reviews the changes in the autism spectrum disorder (ASD) diagnosis in the Diagnostic Statistical Manual (DSM)-5. It reviews the risk factors associated with suicide in the general population and the link between these risk factors and individuals on the autism spectrum. When discussing autism and suicide (as a spectrum), the complexities that the two present influence parents, researchers, and practitioners. As an added dimension of convolution, there are only a small number of published studies in the area of autism and suicide, and many have marked the importance of awareness and connection between autism and suicide. The article presents the most recent and available research on ASDs and suicide. Methodological challenges related to these studies will be discussed as well as the implications for research, practice, and education.

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