Effect of left atrial volume and pulmonary vein anatomy on outcome of nMARQ™ catheter ablation of paroxysmal atrial fibrillation

2016 ◽  
Vol 48 (2) ◽  
pp. 201-207 ◽  
Author(s):  
Giuseppe Stabile ◽  
Matteo Anselmino ◽  
Ezio Soldati ◽  
Ermengildo De Ruvo ◽  
Francesco Solimene ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Pulmonary Vein ◽  
Paroxysmal Atrial Fibrillation ◽  
Left Atrial ◽  
Left Atrial Volume ◽  
Atrial Volume ◽  
Pulmonary Vein Anatomy

scholarly journals Left atrial volume calculated by multi-detector computed tomography may predict successful pulmonary vein isolation in catheter ablation of atrial fibrillation

EP Europace ◽  
2009 ◽  
Vol 11 (10) ◽  
pp. 1289-1294 ◽  
Author(s):  
J. Abecasis ◽  
R. Dourado ◽  
A. Ferreira ◽  
C. Saraiva ◽  
D. Cavaco ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Pulmonary Vein ◽  
Pulmonary Vein Isolation ◽  
Left Atrial ◽  
Left Atrial Volume ◽  
Atrial Volume ◽  
Multi Detector Computed Tomography

scholarly journals Combined assessment of left atrial volume parameters for predicting recurrence of atrial fibrillation following pulmonary vein isolation in patients with paroxysmal atrial fibrillation

2019 ◽  
Vol 36 (5) ◽  
pp. 862-869 ◽  
Author(s):  
Fumitaka Soga ◽  
Hidekazu Tanaka ◽  
Yasuhide Mochizuki ◽  
Jun Mukai ◽  
Makiko Suto ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Pulmonary Vein ◽  
Pulmonary Vein Isolation ◽  
Paroxysmal Atrial Fibrillation ◽  
Left Atrial ◽  
Left Atrial Volume ◽  
Atrial Volume

Left atrial volume at MRI is the main determinant of outcome after pulmonary vein isolation plus linear lesion ablation for paroxysmal-persistent atrial fibrillation

2010 ◽  
Vol 11 (8) ◽  
pp. 593-598 ◽  
Author(s):  
Antonio Montefusco ◽  
Luigi Biasco ◽  
Alessandro Blandino ◽  
Yvonne Cristoforetti ◽  
Marco Scaglione ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Pulmonary Vein ◽  
Pulmonary Vein Isolation ◽  
Left Atrial ◽  
Left Atrial Volume ◽  
Persistent Atrial Fibrillation ◽  
Atrial Volume ◽  
Main Determinant

Abstract 15257: Epicardial and Peri-atrial Fat Attenuation Predict Recurrence in Patients Undergoing Repeat Catheter Ablation for Refractory Atrial Fibrillation

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Mark S Brahier ◽  
Fengwei Zou ◽  
Frank Migliarese ◽  
Milos Tomovic ◽  
Alexandra Taylor ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Logistic Regression ◽  
Adipose Tissue ◽  
Catheter Ablation ◽  
Left Atrial ◽  
Left Atrial Volume ◽  
Epicardial Fat ◽  
Volume Index ◽  
Atrial Volume ◽  
Af Recurrence

Background: Identifying factors predictive of atrial fibrillation (AF) recurrence after catheter ablation (CA) can improve patient selection. It has been hypothesized that inflammatory paracrine signaling by metabolically active adipose tissue induces pathologic changes in surrounding cardiovascular tissue. In fact, fat attenuation on CT has been previously associated with AF recurrence after de novo CA. The purpose of this study was to investigate the predictive qualities of epicardial and peri-atrial adipose tissue in a population undergoing repeat CA. We hypothesized that higher epicardial and left peri-atrial fat attenuation would predict recurrence as markers of increased localized inflammation. Methods: The study population consisted of 84 patients with symptomatic, drug and ablation-refractory AF undergoing repeat CA. All patients had a pre-ablation, contrast-enhanced cardiac CT, which was analyzed for mean fat attenuation in Hounsfield units (HU) and left atrial volume using the post-processing program 3D Slicer. Patients were followed for recurrence of atrial tachyarrhythmias after a 3-month blanking period. We performed logistic regression to adjust for age, sex, BMI, hypertension, smoking history, diabetes, obstructive sleep apnea, and left atrial volume index. Results: Repeat CA patients with recurrence (n=52) had a higher epicardial fat attenuation (-84.8 ±5.6 vs -88.1 ±5.2 HU; p=0.009) and peri-atrial fat attenuation (-81.0 ±4.7 vs -83.2 ±4.3 HU; p=0.036) than those without recurrence (n=32) at a mean follow-up period of 26 ±18 months. Logistic regression analysis showed that epicardial fat attenuation (OR 1.21; p=0.005) and peri-atrial fat attenuation (OR 1.27; p=0.007) are predictive of AF recurrence independent of traditional risk factors. Conclusions: Epicardial and left peri-atrial adipose attenuation are predictive of recurrence in patients undergoing repeat CA for AF.

P5432Invasive assessment by atrial volume-pressure loops of the acute changes in left atrial function induced by pulmonary vein antral isolation

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
A Karanasos ◽  
K Toutouzas ◽  
D Tsiachris ◽  
A Kordalis ◽  
K Tyrovolas ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Elastic Constant ◽  
Pulmonary Vein ◽  
Left Atrial ◽  
Wave Amplitude ◽  
Atrial Function ◽  
Atrial Volume ◽  
Loop Area ◽  
Booster Pump

Abstract Background Atrial volume-pressure loops are considered the best method to assess left atrium (LA) function. Changes in atrial function induced by pulmonary vein (PV) antral isolation of atrial fibrillation (AF) have not been documented thus far using this approach. Purpose We aimed to evaluate changes in LA function in patients with paroxysmal atrial fibrillation (PAF) undergoing catheter ablation by atrial volume-pressure loops. Methods Patients undergoing for the first time catheter ablation of PAF by PV antral isolation and PV-LA junction ablation, as clinically indicated, were enrolled from 2 centers. Each center enrolled consecutive patients undergoing PV antral isolation using the same method i.e. radiofrequency or cryoballoon ablation. Patients with severe mitral stenosis or regurgitation, any prosthetic valve, left atrial thrombus or severe systolic or diastolic dysfunction of the left ventricle were excluded. Before and after the procedure, all patients underwent real-time three-dimensional transthoracic echocardiogram to evaluate volume changes of the LA during an entire cardiac cycle, while simultaneously recording LA pressure by a 6F angiographic catheter following transseptal puncture. After the procedure, LA volume and pressure recordings were gated offline by ECG, and were used to plot the LA pressure as a function of LA volume, thus creating a volume-pressure loop. The A loop area is a measure of the booster pump function of the LA. The V loop area expresses the reservoir function of the LA. Pressure and volume data at the clockwise ascending limb of the volume-pressure loop were fitted to the exponential function P = bxea·V, where P = instantaneous LA pressure; V = LA volume; a is the passive elastic chamber stiffness constant (cm–3) that determines the slope of the exponential curve, and b is the elastic constant (mm Hg). Results 34 patients with PAF were analysed, 12 treated with radiofrequency ablation and 22 with cryoablation. The procedure was uneventful in all cases. Mean LA pressure, A-wave amplitude, and V-wave amplitude were all significantly increased post-procedurally (p<0.001 for all). The area of the A-loop decreased (Post: 40.69 ml·mm Hg [IQR 13.7–71.3] vs. Pre: 64.2 ml·mm Hg [IQR 30.9–86.9]; p=0.001), whereas the area of the V-loop increased (Post: 96.5 ml·mm Hg [IQR 45.1–230.5] vs. Pre: 79.2 ml·mm Hg [IQR 46.9–149.7]; p=0.016). Although the elastic constant increased (p<0.001), there was no significant difference in the passive chamber elastic constant (p=0.30). Conclusion Volume-pressure loops can assess procedural changes in LA function. Catheter ablation of AF is associated with a decrease the LA booster pump function of the LA, and in increase in the left atrial reservoir function. Moreover, there is an increase in LA pressures that is observed in the absence of change in LA stiffness.

scholarly journals Impact of left atrial volume, sphericity, and fibrosis on the outcome of catheter ablation for atrial fibrillation

2018 ◽  
Vol 29 (5) ◽  
pp. 740-746 ◽  
Author(s):  
Dennis W. den Uijl ◽  
Nuno Cabanelas ◽  
Eva M. Benito ◽  
Rosa Figueras ◽  
Francisco Alarcón ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Left Atrial ◽  
Left Atrial Volume ◽  
Atrial Volume
Sign in / Sign up

Export Citation Format

Share Document