scholarly journals Impact of left atrial volume, sphericity, and fibrosis on the outcome of catheter ablation for atrial fibrillation

2018 ◽  
Vol 29 (5) ◽  
pp. 740-746 ◽  
Author(s):  
Dennis W. den Uijl ◽  
Nuno Cabanelas ◽  
Eva M. Benito ◽  
Rosa Figueras ◽  
Francisco Alarcón ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Left Atrial ◽  
Left Atrial Volume ◽  
Atrial Volume

Abstract 15257: Epicardial and Peri-atrial Fat Attenuation Predict Recurrence in Patients Undergoing Repeat Catheter Ablation for Refractory Atrial Fibrillation

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Mark S Brahier ◽  
Fengwei Zou ◽  
Frank Migliarese ◽  
Milos Tomovic ◽  
Alexandra Taylor ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Logistic Regression ◽  
Adipose Tissue ◽  
Catheter Ablation ◽  
Left Atrial ◽  
Left Atrial Volume ◽  
Epicardial Fat ◽  
Volume Index ◽  
Atrial Volume ◽  
Af Recurrence

Background: Identifying factors predictive of atrial fibrillation (AF) recurrence after catheter ablation (CA) can improve patient selection. It has been hypothesized that inflammatory paracrine signaling by metabolically active adipose tissue induces pathologic changes in surrounding cardiovascular tissue. In fact, fat attenuation on CT has been previously associated with AF recurrence after de novo CA. The purpose of this study was to investigate the predictive qualities of epicardial and peri-atrial adipose tissue in a population undergoing repeat CA. We hypothesized that higher epicardial and left peri-atrial fat attenuation would predict recurrence as markers of increased localized inflammation. Methods: The study population consisted of 84 patients with symptomatic, drug and ablation-refractory AF undergoing repeat CA. All patients had a pre-ablation, contrast-enhanced cardiac CT, which was analyzed for mean fat attenuation in Hounsfield units (HU) and left atrial volume using the post-processing program 3D Slicer. Patients were followed for recurrence of atrial tachyarrhythmias after a 3-month blanking period. We performed logistic regression to adjust for age, sex, BMI, hypertension, smoking history, diabetes, obstructive sleep apnea, and left atrial volume index. Results: Repeat CA patients with recurrence (n=52) had a higher epicardial fat attenuation (-84.8 ±5.6 vs -88.1 ±5.2 HU; p=0.009) and peri-atrial fat attenuation (-81.0 ±4.7 vs -83.2 ±4.3 HU; p=0.036) than those without recurrence (n=32) at a mean follow-up period of 26 ±18 months. Logistic regression analysis showed that epicardial fat attenuation (OR 1.21; p=0.005) and peri-atrial fat attenuation (OR 1.27; p=0.007) are predictive of AF recurrence independent of traditional risk factors. Conclusions: Epicardial and left peri-atrial adipose attenuation are predictive of recurrence in patients undergoing repeat CA for AF.

scholarly journals Left atrial stiffness measured by echocardiography is a stronger predictor of atrial fibrillation recurrence after radiofrequency catheter ablation than left atrial volume

2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
J.M Farinha ◽  
M Fonseca ◽  
L Parreira ◽  
A.F Esteves ◽  
A Pinheiro ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Left Atrial ◽  
Radiofrequency Catheter Ablation ◽  
Left Atrial Volume ◽  
Atrial Volume ◽  
Increased Risk ◽  
Unit Increase ◽  
Left Atrial Stiffness ◽  
Af Recurrence

Abstract Introduction Left atrial volume (LAV) is an accepted predictor of atrial fibrillation (AF) recurrence after radiofrequency catheter ablation, stronger than AF duration. Objective The aim of this study was to assess the value of left atrial stiffness (LAS) index as a new parameter evaluated by echocardiography to the prediction of AF recurrence after radiofrequency catheter ablation. Methods We retrospectively studied consecutive patients with paroxysmal or persistent AF submitted to radiofrequency catheter ablation at our institution between 2017 and 2019. We used transthoracic echocardiography to measure the LAV indexed to body surface area and the LAS index, defined as the ratio between the mitral E/e' (obtained with pulsed Doppler at the tip of the mitral leaflets – E, and tissue Doppler imaging at the mitral annulus – e') and the left atrial strain during the reservoir phase (obtained by speckle tracking echocardiography) [LAS index = (E/e') / LA reservoir strain]. The left ventricular ejection fraction (LVEF) was also evaluated. Patients with poor quality echocardiographic images were excluded. We compared 2 groups of patients, according to the recurrence of AF after the blanking period. We analysed the clinical characteristics and echocardiographic findings. The effect of clinical and echocardiography parameters on AF recurrence was evaluated by univariate and multivariate Cox Regression analysis. Results We studied 33 patients, 27 with paroxysmal AF and 6 with persistent AF. Baseline patients' characteristics are presented in Table 1. During a mean follow-up time of 17.9±10.4 months, 7 patients (21%) had AF recurrence, and none died. Patients with AF recurrence had a higher LAS index. After adjusting for confounding variables, only LAS index and LAV were independently associated with AF recurrence (Table 2). Every one unit increase in LAS index was associated with an 11-fold increased risk of AF recurrence (HR 10.86, 95% CI 1.38–85.56; p=0.024), while every one unit increase in LAV index was only associated with a 6% increased risk of AF recurrence (HR 1.06, 95% CI 1.01–1.11, p=0.010). Conclusion LAS index evaluated by echocardiography was a much stronger predictor of AF recurrence after radiofrequency catheter ablation than left atrial volume. FUNDunding Acknowledgement Type of funding sources: None.

scholarly journals Left atrial volume calculated by multi-detector computed tomography may predict successful pulmonary vein isolation in catheter ablation of atrial fibrillation

EP Europace ◽  
2009 ◽  
Vol 11 (10) ◽  
pp. 1289-1294 ◽  
Author(s):  
J. Abecasis ◽  
R. Dourado ◽  
A. Ferreira ◽  
C. Saraiva ◽  
D. Cavaco ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Pulmonary Vein ◽  
Pulmonary Vein Isolation ◽  
Left Atrial ◽  
Left Atrial Volume ◽  
Atrial Volume ◽  
Multi Detector Computed Tomography

scholarly journals Formula to estimate left atrial volume using antero-posterior diameter in patients with catheter ablation of atrial fibrillation

Medicine ◽  
2021 ◽  
Vol 100 (29) ◽  
pp. e26513
Author(s):  
Muktapha Sangsriwong ◽  
Gabriel Cismaru ◽  
Mihai Puiu ◽  
Gelu Simu ◽  
Sabina Istratoaie ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Left Atrial ◽  
Left Atrial Volume ◽  
Atrial Volume

Does Left Atrial Volume and Pulmonary Venous Anatomy Predict the Outcome of Catheter Ablation of Atrial Fibrillation?

2009 ◽  
Vol 20 (9) ◽  
pp. 1005-1010 ◽  
Author(s):  
IRENE HOF ◽  
KARUNA CHILUKURI ◽  
ARMIN ARBAB-ZADEH ◽  
DANIEL SCHERR ◽  
DARSHAN DALAL ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Left Atrial ◽  
Left Atrial Volume ◽  
Atrial Volume ◽  
Venous Anatomy

Effect of left atrial volume and pulmonary vein anatomy on outcome of nMARQ™ catheter ablation of paroxysmal atrial fibrillation

2016 ◽  
Vol 48 (2) ◽  
pp. 201-207 ◽  
Author(s):  
Giuseppe Stabile ◽  
Matteo Anselmino ◽  
Ezio Soldati ◽  
Ermengildo De Ruvo ◽  
Francesco Solimene ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Pulmonary Vein ◽  
Paroxysmal Atrial Fibrillation ◽  
Left Atrial ◽  
Left Atrial Volume ◽  
Atrial Volume ◽  
Pulmonary Vein Anatomy

Left atrial volume is more important than the type of atrial fibrillation in predicting the long-term success of catheter ablation

2015 ◽  
Vol 184 ◽  
pp. 56-61 ◽  
Author(s):  
Francisco Moscoso Costa ◽  
António Miguel Ferreira ◽  
Sílvia Oliveira ◽  
Pedro Galvão Santos ◽  
Anai Durazzo ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Left Atrial ◽  
Left Atrial Volume ◽  
Atrial Volume
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