zinc oxide nanoparticles
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2022 ◽  
Vol 3 ◽  
pp. 100041
M.A. Kareem ◽  
I.T. Bello ◽  
H.A. Shittu ◽  
P. Sivaprakash ◽  
O. Adedokun ◽  

2022 ◽  
Vol 11 (1) ◽  
pp. 1-9
Lijuan Song

In order to meet the needs of ecological buildings, it is necessary to improve the speed of sewage treatment. Therefore, this study analyzed the impact of zinc oxide nanoparticles on the water supply and drainage of ecological buildings. In the experiment, zinc oxide nanoparticles were selected and the experimental environment was set up to study the treatment effect of nano particles on water supply and drainage wastewater. The experimental results show that: the application of ZnO nanoparticles in water supply and drainage can effectively remove trace elements in sewage and reduce the eutrophication of groundwater; zinc oxide nanoparticles can change the morphology of mold group in sewage and inhibit the growth of sewage. The application of ZnO nanoparticles in the water supply and drainage of ecological buildings can effectively improve the water purification rate and improve the recycling efficiency of water resources.

2022 ◽  
Vol 12 (2) ◽  
pp. 710
Fohad Mabood Husain ◽  
Faizan Abul Qais ◽  
Iqbal Ahmad ◽  
Mohammed Jamal Hakeem ◽  
Mohammad Hassan Baig ◽  

Global emergence and persistence of the multidrug-resistant microbes have created a new problem for management of diseases associated with infections. The development of antimicrobial resistance is mainly due to the sub-judicious and unprescribed used of antimicrobials both in healthcare and the environment. Biofilms are important due to their role in microbial infections and hence are considered a novel target in discovery of new antibacterial or antibiofilm agents. In this article, zinc oxide nanoparticles (ZnO-NPs) were prepared using extract of Plumbago zeylanica. ZnO-NPs were characterized and then their antibiofilm activity was tested against Gram-positive and Gram-negative bacteria. The ZnO-NPs were polydispersed, and the average size was obtained as 24.62 nm. The presence of many functional groups indicated that phytocompounds of P. zeylanica were responsible for the synthesis, capping, and stabilization of ZnO-NPs. Synthesized NPs inhibited the biofilm formation of E. coli, S. aureus, and P. aeruginosa by 62.80%, 71.57%, and 77.69%, respectively. Likewise, concentration-dependent inhibition of the EPS production was recorded in all test bacteria. Microscopic examination of the biofilms revealed that ZnO-NPs reduced the bacterial colonization on solid support and altered the architecture of the biofilms. ZnO-NPs also remarkably eradicated the preformed biofilms of the test bacteria up to 52.69%, 59.79%, and 67.22% recorded for E. coli, S. aureus, P. aeruginosa, respectively. The findings reveal the ability of green synthesized zinc oxide nanoparticles to inhibit, as well as eradicate, the biofilms of Gram-positive and Gram-negative bacteria.

2022 ◽  
Nidhi chaudhary ◽  
Manish Pratap Singh ◽  
Preeti Sirohi ◽  
Shadma Afzal ◽  
Nand K. Singh

Abstract ObjectiveIn the present study, we green synthesized ZnO NPs (zinc oxide nanoparticles) from Senna occidentalis leaf extract which were subsequently assessed for their cytotoxic and antioxidant activity on colon cancer SW480 cell line.Results Zinc oxide nanoparticles were characterized by using UV-Vis spectroscopy, X-ray diffractometer (XRD), Particle size analyzer (PSA), Fourier transform infrared spectroscopy (FTIR), Field emission scanning electron microscopy (FE-SEM), Energy-dispersive X-ray (EDS) and atomic force microscope (AFM) analysis. The PSA, XRD and AFM showed 20-50 nm size and nearly cuboidal and irregular shaped of the ZnO NPs. The synthesized ZnO nanoparticles were evaluated for their anticancer activity on human colon cancer cell line (SW480) by using MTT and neutral red uptake assay. The SW480 colon cancer cells were treated with various concentrations of ZnO NPs in the range of 20–100 µg/ml for 2 hrs. The result showed that ZnO NPs could reduce cell viability of SW480 cells up to 50% at the concentration of 100 µg/ml and induce membrane leakage in a concentration dependent manner.ConclusionThe anticancer activity of zinc oxide nanoparticles has showed that these can be used as effective anti-cancer agent against colon cancer cell lines (SW480).

Bruna Lallo da Silva ◽  
Mariana Marin Garcia ◽  
João Augusto Oshiro-Junior ◽  
Mariana Rillo Sato ◽  
Bruno Leonardo Caetano ◽  

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