Study on the molecular structure and thermal stability of pyrimidine nucleoside analogs

2015 ◽  
Vol 120 (1) ◽  
pp. 1009-1025 ◽  
Author(s):  
Xue-Jie Wang ◽  
Jin-Zong You
Keyword(s):  
Molecular Structure ◽  
Thermal Stability ◽  
Nucleoside Analogs ◽  
Pyrimidine Nucleoside ◽  
Thermal Stability Of

Synthesis and Characterization of Some Functional Luminol Derivatives with Aromatic Substituted Groups

2011 ◽  
Vol 197-198 ◽  
pp. 606-609 ◽  
Author(s):  
Ti Feng Jiao ◽  
Yuan Yuan Xing ◽  
Jing Xin Zhou ◽  
Wei Wang
Keyword(s):  
Molecular Structure ◽  
Thermal Stability ◽  
Molecular Structures ◽  
Synthesis And Characterization ◽  
Functional Material ◽  
Aromatic Substituent ◽  
The Difference ◽  
Imide Group ◽  
Thermal Stability Of

Some functional luminol derivatives with aromatic substituted groups have been designed and synthesized from the reaction of the corresponding aromatic acyl chloride precursors with luminol. It has been found that depending on the size of aromatic groups, the formed luminol derivatives showed different properties, indicating distinct regulation of molecular skeletons. UV and IR data confirmed commonly the formation of imide group as well as aromatic segment in molecular structures. Thermal analysis showed that the thermal stability of luminol derivatives with p-phthaloyl segment was the highest in those derivatives. The difference of thermal stability is mainly attributed to the formation of imide group and aromatic substituent groups in molecular structure. The present results have demonstrated that the special properties of luminol derivatives can be turned by modifying molecular structures of objective compounds with proper substituted groups, which show potential application in functional material field and ECL sensor.

Systematic Evaluation of Hybridization Property and Photo-Crosslinking Ability of Modified Oligonucleotides Containing Benzophenone-Bearing Glycol Nucleoside Analogs

2020 ◽  
Vol 38 ◽  
pp. 57-62
Author(s):  
Masatoshi Sunaga ◽  
Dai Motegi ◽  
Yuya Motegi ◽  
Kazuo Shinozuka ◽  
Tomohisa Moriguchi
Keyword(s):  
Thermal Stability ◽  
Regulation Of Gene Expression ◽  
Covalent Bond ◽  
Nucleoside Analogs ◽  
Systematic Evaluation ◽  
Crosslinking Reaction ◽  
Triplex Forming Oligonucleotide ◽  
Triplex Structure ◽  
The One ◽  
Thermal Stability Of

Antigene technology is the one strategy for the artificial regulation of gene expression by the formation of triple structure on triplex forming oligonucleotide (TFO) with dsDNA. For the enhancement of the thermal stability of triplex structure, photo-crosslinking reaction is attractive by the covalent bond formation between TFO and dsDNA. In this paper, we designed the novel TFOs containing benzophenone moiety as a photo-crosslinkable agent. Several types of glycol nucleoside analogs having glycol scaffold and benzophenone residues with different linker length were prepared, and the these were incorporated into TFOs. The thermal stability of triplex and the photo-crosslinking reaction efficiency of TFOs toward dsDNA was systematically evaluated.

Synthesis and Characterization of Functional Cholesteryl Substituted Luminol Derivative

2011 ◽  
Vol 694 ◽  
pp. 565-569 ◽  
Author(s):  
Ti Feng Jiao ◽  
Yuan Yuan Xing ◽  
Jing Xin Zhou
Keyword(s):  
Molecular Structure ◽  
Thermal Stability ◽  
Functional Material ◽  
Substituent Group ◽  
The Difference ◽  
Imide Group ◽  
Luminol Derivative ◽  
Molecular Skeleton ◽  
Thermal Stability Of

Functional luminol derivative with cholesteryl substituted group has been designed and synthesized from the reaction of the corresponding precursor cholesteryl chloroformate with luminol. It has been found that depending on cholesteryl substituted group, the formed luminol derivative showed different properties, indicating distinct regulation of molecular skeleton. UV and IR data confirmed commonly the formation of imide group as well as cholesteryl segment in molecular structure. Thermal analysis showed that the thermal stability of luminol derivative with cholesteryl segment was different from luminol. The difference of thermal stability is mainly attributed to the formation of imide group and cholesteryl substituent group in molecular structure. The present results have demonstrated that the special properties of luminol derivative can be turned by modifying molecular structure of objective compound with proper substituted groups, which show potential application in functional material fields such as liquid crystal and ECL sensor.

Remarkable Influence of molecular structure of N,N'-unsymmetrically substituted 1,3-amidinate and -guanidinate on the Volatility and the Thermal Stability of Precursors for HfO2 Films via Liquid Injection-MOCVD

2019 ◽  
Vol 25 (8) ◽  
pp. 151-158 ◽  
Author(s):  
Mohamad Eleter ◽  
Stephane Daniele ◽  
Virginie Brize ◽  
Catherine Dubourdieu ◽  
Christophe Lachaud ◽  
...  
Keyword(s):  
Molecular Structure ◽  
Thermal Stability ◽  
Liquid Injection ◽  
Thermal Stability Of
Sign in / Sign up

Export Citation Format

Share Document