Pre-Pregnancy Body Mass Index and Weight Gain During Pregnancy: Relations with Gestational Diabetes and Hypertension, and Birth Outcomes

Abstract Background Pre-pregnancy body mass index and gestational weight gain were related to perinatal outcomes. It was not know the changes of pre-pregnancy body mass index, weight gain during pregnancy and its effect on perinatal outcomes in two-child women.Methods This was a retrospective study. Data of single term women delivered in the First Affiliated Hospital of Sun Yat-sen University were collected from July 2017 to June 2018. Gestational weight gain criteria of the American Institute of Medical Research and pre-pregnancy body mass index classes were used to evaluate the effects on pregnancy outcomes.Results A total of 3049 cases were enrolled in the study. Overweight cases was 9.0% and obesity was 2.4%. The weight gain of the two-child women was less than that of primipara(12.4±3.9vs13.3±4.0kg, P<0.001). The proportion of primipara with excessive weight gain was higher compared to two-child women(20.1%versus17.3%, P<0.001). There were 40.0% overweight primipara and 55.2% of two-child women had excessive weight gain. And 40.5% primipara and 54.5% two-child women of obesity had excessive weight gain during pregnancy. Obese primipara increased the risk of pre-eclampsia (aOR2.38, 95%CI 0.76-7.46). And the odds of diabetes mellitus and large for gestational age also increased in this group (aOR3.49, 95%CI 1.46-8.35 and aOR7.65, 95%CI 1.83-31.97, respectively). Two-child women had similar results. Underweight primipara with excessive weight gain increased the pre-eclampsia risk (aOR2.26, 95%CI 0.29-17.46). Normal weight and overweight/obese primipara also had similar results. But in two-child women, only overweight/obesity increased the risk of pre-eclampsia (aOR2.01, 95%CI 0.41-9.98). Underweight two-child women with less weight gain increased the risk of diabetes(aOR2.06, 95%CI 0.43-9.8). Two-child women with overweight/obese increased the odds of LGA even if they had less weight gain(aOR2.58, 95%CI 0.11-63.22). Normal weight primipara and two-child women with overweight and obese with excessive weight gain had similar results. On the other way, underweight primipara with less weight gain increased the risk of SGA(aOR1.74, 95%CI 0.81-3.76).Conclusions Gestational weight gain of two-child women was less than primipara. Overweight/obese women with excessive weight gain of two-child women increased the risk of adverse outcomes.

Download Full-text

Associations of maternal pre-pregnancy body mass index and gestational weight gain with birth outcomes in Shanghai, China

Scientific Reports ◽

10.1038/srep41073 ◽

2017 ◽

Vol 7 (1) ◽

Cited By ~ 17

Author(s):

Lingli Xiao ◽

Guodong Ding ◽

Angela Vinturache ◽

Jian Xu ◽

Yifang Ding ◽

...

Keyword(s):

Body Mass Index ◽

Weight Gain ◽

Gestational Weight Gain ◽

Body Mass ◽

Birth Outcomes ◽

Gestational Weight

Download Full-text

Effect of Parity, Maternal Body Mass Index, Maternal Weight Gain During Pregnancy, Stage of Labor, and Amniotic Fluid Volume on Ultrasonographic Estimation of Fetal Weight

Istanbul Medical Journal ◽

10.5152/imj.2015.96977 ◽

2015 ◽

Vol 16 (3) ◽

pp. 105-110 ◽

Cited By ~ 1

Author(s):

Hasene Ozcam ◽

Gonul Cimen ◽

Nil Atakul ◽

Cihangir Uzuncakmak ◽

Ahmet Guldas ◽

...

Keyword(s):

Body Mass Index ◽

Weight Gain ◽

Amniotic Fluid ◽

Body Mass ◽

Fetal Weight ◽

Maternal Body Mass Index ◽

Maternal Weight Gain ◽

Maternal Weight ◽

Amniotic Fluid Volume ◽

Weight Gain During Pregnancy

Download Full-text

The Effects of Pre-Pregnancy Body Mass Index and Weight Gain During Pregnancy on Perinatal Outcomes: A Retrospective Cohort Study

Gynecology Obstetrics and Reproductive Medicine ◽

10.21613/gorm.2021.1149 ◽

2021 ◽

Author(s):

Engin Yurtcu ◽

Sibel Mutlu ◽

Enis Ozkaya

Keyword(s):

Body Mass Index ◽

Weight Gain ◽

Preterm Delivery ◽

Body Mass ◽

Retrospective Cohort ◽

Neonatal Intensive Care ◽

Perinatal Outcomes ◽

Pregnancy Weight Gain ◽

Pregnancy Weight ◽

Weight Gain During Pregnancy

OBJECTIVE: To investigate the effects of pre-pregnancy body mass index and weight gain during pregnancy on perinatal outcomes and delivery mode. STUDY DESIGN: In this retrospective cohort study, 722 pregnant women giving birth between 2018-2019 were screened from our hospital database. First, they were divided into four groups according to their pre-pregnancy body mass index (low-weight/normal-weight/overweight/obese), and then they were redivided into three groups according to pregnancy weight gain (≤7/8-15/≥16 kg). Prenatal body mass index and pregnancy weight gain were compared concerning maternal-neonatal results and mode of delivery. RESULTS: According to pre-pregnancy body mass index, among the obese pregnant group, gestational diabetes mellitus (p<0.001), preeclampsia (p=0.029), preterm delivery (p=0.011) and cesarean delivery (p=0.061) rates were more common. As the body mass index increases, neonatal intensive care requirement (p=0.0020) and low 1st minute APGAR scores (p=0.019) were detected more frequently. However, as pregnancy weight gain decreased, preterm delivery (p=0.041) increased. Also, birth weight increased (p<0.001) with the weight gain of the pregnant. Pregnant women gaining more than 16 kg were associated either with a lower <2500 g or a higher birth weight risk >4000 g. CONCLUSION: Pre-pregnancy high body mass index is associated with negative obstetric outcomes like gestational diabetes, preeclampsia, preterm delivery, and increased cesarean rates, and poor fetal incidences with a low APGAR score and high neonatal intensive care admission rates.

Download Full-text