Juvenile idiopathic arthritis patients and their skeletal status: possible role of vitamin D receptor gene polymorphism

2014 ◽  
Vol 41 (4) ◽  
pp. 1937-1943 ◽  
Author(s):  
M. M. Kostik ◽  
A. M. Smirnov ◽  
G. S. Demin ◽  
L. A. Scheplyagina ◽  
V. I. Larionova
Keyword(s):  
Vitamin D ◽  
Juvenile Idiopathic Arthritis ◽  
Gene Polymorphism ◽  
Vitamin D Receptor ◽  
Receptor Gene ◽  
Vitamin D Receptor Gene ◽  
Receptor Gene Polymorphism ◽  
Skeletal Status

95-P: Role of vitamin D receptor gene polymorphism in tuberculosis

2007 ◽  
Vol 68 (1) ◽  
pp. S62
Author(s):  
Angel R. Villasmil ◽  
Mercedes T. Fernandez-Mestre ◽  
Violeta Ogando ◽  
Zulay E. Layrisse
Keyword(s):  
Vitamin D ◽  
Gene Polymorphism ◽  
Vitamin D Receptor ◽  
Receptor Gene ◽  
Vitamin D Receptor Gene ◽  
Receptor Gene Polymorphism

scholarly journals The Role of Apa-I Vitamin D Receptor Gene Polymorphism in Type 2 Diabetes Mellitus

2021 ◽  
Vol 9 (A) ◽  
pp. 129-133
Author(s):  
Mutiara Indah Sari ◽  
Rusdiana Rusdiana ◽  
Milahayati Daulay
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Gene Polymorphism ◽  
Vitamin D Receptor ◽  
Receptor Gene ◽  
Vitamin D Receptor Gene ◽  
Receptor Gene Polymorphism

BACKGROUND: Type 2 diabetes mellitus (T2DM) is a chronic metabolic syndrome caused by insulin secretion abnormalities, insulin action, or both. Gene polymorphism is a risk factor of T2DM. AIM: This study aims to see the role of Apa-I Vitamin D receptor gene polymorphism on T2DM. METHODS: This study was an analytic observational with a case–control approach, consisting of 70 T2DM patients and 70 healthy subjects as a control. Genotyping of the Apa-I Vitamin D receptor gene polymorphism was performed using the polymerase chain reactions-restriction fragment length polymorphisms method. The role of the Apa-I Vitamin D receptor gene polymorphism and the risk of T2DM were analyzed using the Chi-square test. RESULTS: The results showed that there was a significant association between codominant (TT genotype); dominant; recessive models of the Apa-I Vitamin D receptor gene polymorphism with the risk of T2DM (p < 0.05; odds ratio [OR] = 0.204, 95% confidence interval [CI] = 0.063–0.662; OR = 0.337, 95% CI = 0.113–1.004; OR = 0.367, 95% CI = 0.180–0.747, respectively), but not in codominant (GT genotype) and over-dominant models (p > 0.05). CONCLUSION: This study shows a role of the codominant (TT genotype); dominant; recessive models of the Apa-I Vitamin D receptor gene polymorphism on T2DM, but not in codominant (GT genotype) and over-dominant models.

Vitamin D receptor gene polymorphism influences lipid profile in patients with juvenile idiopathic arthritis

2018 ◽  
Vol 38 (1) ◽  
pp. 117-124 ◽  
Author(s):  
Jelena Bašić ◽  
Jelena Vojinović ◽  
Tatjana Jevtović-Stoimenov ◽  
Milena Despotović ◽  
Gordana Sušić ◽  
...  
Keyword(s):  
Vitamin D ◽  
Juvenile Idiopathic Arthritis ◽  
Gene Polymorphism ◽  
Lipid Profile ◽  
Vitamin D Receptor ◽  
Receptor Gene ◽  
Vitamin D Receptor Gene ◽  
Receptor Gene Polymorphism
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