The Basolateral Nucleus in the System of Reproductive Centers in the Amygdaloid Body of the Brain

2016 ◽  
Vol 46 (6) ◽  
pp. 652-658 ◽  
Author(s):  
A. V. Akhmadeev ◽  
L. F. Galieva ◽  
L. B. Kalimullina
Author(s):  
Индира Садртдинова ◽  
Indira Sadrtdinova ◽  
Зухра Хисматуллина ◽  
Zuhra Hismatullina

The monograph deals with the problems of general morphology of the amygdaloid body and for the first time the assessment of structural and functional changes in the anterior cortical nucleus of the amygdaloid body of the brain of WAG/Rij female rats (the recognized model of man’s absence epilepsy) in response to the modulating influence of sex hormones is made by means of a modern complex of research methods (electrophysiological, morphometric, histologic, immunohistochemical, submicroscopical and statistical ones). The changes in the electroencephalographic parameters of the anterior cortical nucleus, the reactive changes in neurons, glial anterior cortical nuclei of the amygdaloid body of the brain of WAG/Rij female rats at sex hormones deficiency and after the substitution therapy with 17β-estradiol in combination with progesterone are described in detail. The results of immunohistochemical analysis of astrocytic glia, of the analysis of synapsoarchitectonics and ultrastructural changes in neurons, glial cells, neuropil of the anterior cortical nucleus of the amygdaloid body of WAG / Rij rats at experimentally caused sex hormone deficiency and on the background of exogenous injection of 17β-estradiol in combination with progesterone into ovariectomized female rats are presented for the first time. The obtained new data on the morphofunctional features of the anterior cortical nucleus of the amygdaloid body of the brain significantly expand the notion of reactive changes in the anterior cortical nucleus at different levels of sex hormones and can be used by researchers of various profiles in studying this structure of the brain. The monograph is intended for neurobiologists of various specialities (neuromorphologists, neurophysiologists, neuroendocrinologists, neurochemists, etc.) engaged in the research of the amygdaloid body and the limbic system of the brain.


1995 ◽  
Vol 41 (2) ◽  
pp. 44-44
Author(s):  
V. I. Kandror ◽  
I. G. Akmayev ◽  
L. B. Kalimullina

Due to the fact that endocrine functions are inherent in almost all areas of the brain, the hypothalamus ceases to be an exclusive object of research by neuroendocrinologists. An increasing number of brain regions are being drawn into the orbit of neuroendocrine research. Among them, the limbic region of the brain attracts the most attention, an important link of which, participating in the regulation of reproductive functions, is the amygdala complex (MC). Latest fundamental analysis, including structural, concerning histophysiologic and neuroendocrinological approaches are presented in the reviewed book. It must be admitted that the publication of this book is timely. Drawing on many years of experience of their own research and extensive literature, the authors analyze in detail the features of the structural organization of this region of the brain and the mechanisms of its interaction with the centers of the brain that control reproductive function. The book consists of a brief introduction, three main chapters and a conclusion. In addition to a large summary of the cited literature, attracts the attention of a rich and very illustrative material. The latter includes a volumetric reconstruction of the entire MC of the brain and its individual components, the reconstruction of the MC on a series of histological sections, each of which is further reproduced in the form of a schematic diagram, and finally, a series of the most informative sections of the MC, reflecting the main structures of this brain region on the frontal sections. Due to its uniqueness, the illustrative material can be used as an atlas of the structural organization of the MC, and therefore it is of independent value.


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