In Vivo Neurochemical Characterization of Developing Guinea Pigs and the Effect of Chronic Fetal Hypoxia

2016 ◽  
Vol 41 (7) ◽  
pp. 1831-1843 ◽  
Author(s):  
Wen-Tung Wang ◽  
Phil Lee ◽  
Yafeng Dong ◽  
Hung-Wen Yeh ◽  
Jieun Kim ◽  
...  
Keyword(s):  
Guinea Pigs ◽  
Fetal Hypoxia

Characterization of in vitro and in vivo platelet responses to thrombin and thrombin receptor-activating peptides in guinea pigs

1997 ◽  
Vol 321 (1) ◽  
pp. 129-135 ◽  
Author(s):  
Peter J.S. Chiu ◽  
Glen G. Tetzloff ◽  
Carolyn Foster ◽  
Madhu Chintala ◽  
Edmund J. Sybertz
Keyword(s):  
Guinea Pigs ◽  
Thrombin Receptor

In vivo characterization of B2 receptors mediating hypotension in anesthetized rabbits and guinea pigs

1996 ◽  
Vol 33 (1-3) ◽  
pp. 284-286 ◽  
Author(s):  
F. Gobeil ◽  
C. Filteau ◽  
L.H. Pheng ◽  
X.K. Nguyen-Le ◽  
D. Regoli
Keyword(s):  
Guinea Pigs ◽  
B2 Receptors ◽  
In Vivo Characterization

Aluminium uptake from some foods by guinea pigs and the characterization of aluminium in in vivo intestinal digesta by SEC-ICP-MS

1994 ◽  
Vol 32 (8) ◽  
pp. 697-705 ◽  
Author(s):  
L.M.W. Owen ◽  
H.M. Crews ◽  
N.J. Bishop ◽  
R.C. Massey
Keyword(s):  
Guinea Pigs ◽  
Icp Ms

scholarly journals Characterization of the mechanisms underlying the colonic muscle relaxation induced by lipopolysaccharide in guinea pigs in vivo

2012 ◽  
Vol 23 (8) ◽  
pp. 333-341
Author(s):  
Norifumi Ninomiya ◽  
Kayo Nemoto ◽  
Masamune Kuno
Keyword(s):  
Guinea Pigs ◽  
Muscle Relaxation

Functional characterization of human brown adipose tissue metabolism

2020 ◽  
Vol 477 (7) ◽  
pp. 1261-1286 ◽  
Author(s):  
Marie Anne Richard ◽  
Hannah Pallubinsky ◽  
Denis P. Blondin
Keyword(s):  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Functional Characterization ◽  
Human Infants ◽  
Positron Emission ◽  
Brown Adipose ◽  
Treatment Of Obesity ◽  
And Function

Brown adipose tissue (BAT) has long been described according to its histological features as a multilocular, lipid-containing tissue, light brown in color, that is also responsive to the cold and found especially in hibernating mammals and human infants. Its presence in both hibernators and human infants, combined with its function as a heat-generating organ, raised many questions about its role in humans. Early characterizations of the tissue in humans focused on its progressive atrophy with age and its apparent importance for cold-exposed workers. However, the use of positron emission tomography (PET) with the glucose tracer [18F]fluorodeoxyglucose ([18F]FDG) made it possible to begin characterizing the possible function of BAT in adult humans, and whether it could play a role in the prevention or treatment of obesity and type 2 diabetes (T2D). This review focuses on the in vivo functional characterization of human BAT, the methodological approaches applied to examine these features and addresses critical gaps that remain in moving the field forward. Specifically, we describe the anatomical and biomolecular features of human BAT, the modalities and applications of non-invasive tools such as PET and magnetic resonance imaging coupled with spectroscopy (MRI/MRS) to study BAT morphology and function in vivo, and finally describe the functional characteristics of human BAT that have only been possible through the development and application of such tools.

In vivo characterization of plaque composition in late Cardiac Allograft Vasculopathy

2008 ◽  
Vol 7 ◽  
pp. 196-196
Author(s):  
T OBERNDORFER ◽  
M FRICK ◽  
J DOERLER ◽  
C MUSSNER ◽  
D HOEFER ◽  
...  
Keyword(s):  
Cardiac Allograft Vasculopathy ◽  
Cardiac Allograft ◽  
Plaque Composition ◽  
Allograft Vasculopathy ◽  
In Vivo Characterization

Involvement of 5-Hydroxytryptamine in Platelet Aggregation In Vivo in Rats and Guinea Pigs

1989 ◽  
Vol 61 (03) ◽  
pp. 463-467 ◽  
Author(s):  
G M Smith
Keyword(s):  
Platelet Count ◽  
Guinea Pigs ◽  
Platelet Adhesion ◽  
Adenosine Diphosphate ◽  
Rate Of Return ◽  
Low Doses ◽  
Dose Dependent ◽  
Higher Doses ◽  
Rat Platelets

SummaryIn this study, 5-hydroxytryptamine (5-HT) caused a dose- dependent fall in the circulating platelet count suggesting that 5-HT receptors are activated in rat platelets to cause platelet adhesion and aggregation. When low doses of adenosine diphosphate (ADP) were simultaneously injected with 5-HT, there was a significant potentiation of the responses to ADR Ketanserin significantly reduced the potentiated responses. When higher doses of ADP were infused with bolus injections of 5-HT there was no potentiation and ketanserin did not reduce these responses. Ketanserin did not inhibit the collagen-induced fall in circulating platelet count, but did significantly increase the rate of return to the basal platelet count compared with control. 5-HT did not cause a fall in platelet count in guinea-pigs

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