Antihyperglycemic and Antihyperlipidemic Evaluation of Zingiber officinale, Anethum graveolens and Citrullus colocynthis Extracts with Different Polarities in Streptozotocin-Induced Diabetic Rats

2022 ◽  
Author(s):  
Abbas Ahmadi ◽  
Mehrdad Roghani ◽  
Meysam Parsianfard ◽  
Faeze-sadat Seyedmomeni ◽  
Sahar Gheraati ◽  
...  
Keyword(s):  
Zingiber Officinale ◽  
Diabetic Rats ◽  
Citrullus Colocynthis ◽  
Anethum Graveolens

Investigating the effects of Citrullus colocynthis on cognitive performance and anxiety-like behaviors in STZ-induced diabetic rats

2021 ◽  
pp. 1-18
Author(s):  
Mohammad Amin Rajizadeh ◽  
Amir Hashem Aminizadeh ◽  
Khadijeh Esmaeilpour ◽  
Mohammad Abbas Bejeshk ◽  
Asieh Sadeghi ◽  
...  
Keyword(s):  
Cognitive Performance ◽  
Diabetic Rats ◽  
Citrullus Colocynthis

EFFECT OF DILL (ANETHUM GRAVEOLENS) AND PARSLEY (PETROSELENIUM CRISPUM) ESSENTIAL OILS ON DIABETIC RATS

2012 ◽  
Vol 90 (1) ◽  
pp. 219-235
Author(s):  
ABDEL-MENEM M. EISSA ◽  
SAEB A. HAFEZ ◽  
NAGLAA H. M. HASSANEN ◽  
ESRAA A. M. MOSA
Keyword(s):  
Essential Oils ◽  
Diabetic Rats ◽  
Anethum Graveolens

scholarly journals Effects of the Hydroalcoholic Extract of Zingiber officinale on Arginase I Activity and Expression in the Retina of Streptozotocin-Induced Diabetic Rats

2017 ◽  
Vol In press (In press) ◽  
Author(s):  
Nasrin Lamuchi-Deli ◽  
Mohammad Aberomand ◽  
Hossein Babaahmadi-Rezaei ◽  
Ghorban Mohammadzadeh
Keyword(s):  
Zingiber Officinale ◽  
Diabetic Rats ◽  
Hydroalcoholic Extract ◽  
Arginase I

scholarly journals Short- and long-term effects of various Citrullus colocynthis seed extracts in normal and streptozotocin-induced diabetic rats

2012 ◽  
Vol 30 (6) ◽  
pp. 1528-1536 ◽  
Author(s):  
NABILA BENARIBA ◽  
RABEH DJAZIRI ◽  
BOUCHRA HANANE ZERRIOUH ◽  
WAFAA BELLAKHDAR ◽  
EMELINE HUPKENS ◽  
...  
Keyword(s):  
Diabetic Rats ◽  
Citrullus Colocynthis ◽  
Long Term Effects ◽  
Short And Long Term ◽  
Seed Extracts

Amelioration of pancreatic and renal derangements in streptozotocin-induced diabetic rats by polyphenol extracts of Ginger (Zingiber officinale) rhizome

2015 ◽  
Vol 22 (4) ◽  
pp. 203-209 ◽  
Author(s):  
Mutiu Idowu Kazeem ◽  
Musbau Adewunmi Akanji ◽  
Musa Toyin Yakubu
Keyword(s):  
Zingiber Officinale ◽  
Diabetic Rats

scholarly journals Preventive Role of Zingiber Officinale against Hyperglycemia in Alloxan Induced Diabetic Rats

2019 ◽  
Vol 30 (Number 1) ◽  
pp. 26-29
Author(s):  
S Sultana ◽  
N Y Mili ◽  
R Afroz ◽  
S Parveen
Keyword(s):  
Blood Glucose ◽  
Zingiber Officinale ◽  
Diabetic Control ◽  
Diabetic Rats ◽  
Control Group ◽  
Standard Diet ◽  
Group Iii ◽  
Diabetic Control Group ◽  
Glucose Estimation ◽  
Preventive Role

The experimental animal study was undertaken to investigate the preventive role ginger juice against hyperglycemia in alloxan induced diabetic rats.Male wistar rats,(130-150)gm wt fed on standard diet and water ad libitum, were divided into 3 groups(n=6) in each group: Group-L non-diabetic control group, Group-II, diabetic control & Group-III, normal rats pretreated with ginger before they were made diabetics. Diabetes was induced by inj. alloxan 150mg/kg body wt.,tp (Group-IL on 2nd day & Group-Ill, on the 9th day).Rats having blood glucose level of more than 7mmol/L on day 5(72 hours after alloxan inj) were considered diabetic & selected for experiment. Rats of Group-Ill received Zingiber officinale (ginger juice) (4m1/kg.body,wt orally) for 7 days (day 2-day8) through Pyles tube before alloxan induction & 3days after the induction. On day 12, animals were sacrificed under light ether anaesthesia, blood was collected by cardiac puncture for blood glucose estimation. Pretreatment with Zingiber officinale (ginger) juice significantly (p<0.01) reduced alloxan induced hyperglycemia.Zingiber officinale (ginger) is one of the most widely used spices and is reputed to have medicinal properties against diabetes mellitus. This study suggests that pretreatment with Zingiber officinale(ginger) prevents the development of hyperglycemia in alloxan induced diabetic rats.

scholarly journals Effect of Aqueous Extract of Zingiber officinale (Ginger) on Some Biochemical Parameters in Streptozotocin-induced Diabetes Rats

2019 ◽  
pp. 1-8
Author(s):  
M. K. Jiyil ◽  
C. D. Luka ◽  
C. E. Mafuyai ◽  
N. Pamela
Keyword(s):  
Body Weight ◽  
Biochemical Parameters ◽  
Zingiber Officinale ◽  
Diabetic Control ◽  
Diabetic Rats ◽  
The Body ◽  
Albino Rats ◽  
Ginger Extract ◽  
Hematological Analysis ◽  
Treatment Of Diabetes

Background: Appreciable number of medicinal plants are used for the treatment of diabetes in Nigeria. Aim of the Study: The present study aimed to investigate the antidiabetic activity of Zingiber officinale extracts and its potential mechanisms in streptozotocin-induced diabetic rats. Study Duration: The period of the study was done on 30th September, 2018 at the Department of Biochemistry, Faculty of Basic Medical Sciences, university of Jos, Nigeria. Methodology: Albino rats of Wistar strain weighing between 130 g to 160 g were induced with single freshly prepared streptozotocin (55 mg/kg body weight). Diabetes was confirmed after forty eight hours in streptozotocin -induced rats showing fasting blood glucose levels > 10 mmol/l. The rats were randomly divided into four (4) experimental groups (n = 4). A (Control diabetic group fed with normal feed), Group B (Normal control fed with normal feed), Group Group C (Diabetic rats treated with 400 mg/Kg body weight extract of ginger and Group D, (Diabetic rats are treated with 400 mg/Kg body weight of metformin). After 8 days the animals were sacrificed and blood samples were collected for biochemical and hematological analysis. Changes in the animal body weights were also measured within the period. Results: From the results, it was observed that treatment of rats with extract of ginger compensates for the reduction of body weight, and caused an increase in the body weight of the treated rats (+11.5%) in contrast to 24.8% reduction observed in diabetic control. In the same order, serum glucose significantly decreased (p<0.05) after the 8-day treatment compared to diabetic control. The extent of reversal of hyperglycemia in the ginger extract treated animals compared well with the metformin treated group. The results, therefore, showed that ginger extract has a significant (p<0.05) hypoglycemic effect in diabetic rats and moreover, elevations in the measured biochemical parameters were significantly (p<0.05) attenuated in rats treated with ginger extract. Conclusion: Zingiber officinale extracts has a significant effect on some biochemical parameters and hematological assays. These provide scientific evidence to confirm the traditional use of Z. officinale in the treatment of diabetes mellitus.

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