Marked Differences in the Effect of Antiepileptic and Cytostatic Drugs on the Functionality of P-Glycoprotein in Human and Rat Brain Capillary Endothelial Cell Lines

Dana Alms; Maren Fedrowitz; Kerstin Römermann; Andreas Noack; Wolfgang Löscher

doi:10.1007/s11095-013-1264-4

Marked Differences in the Effect of Antiepileptic and Cytostatic Drugs on the Functionality of P-Glycoprotein in Human and Rat Brain Capillary Endothelial Cell Lines

Pharmaceutical Research ◽

10.1007/s11095-013-1264-4 ◽

2014 ◽

Vol 31 (6) ◽

pp. 1588-1604 ◽

Cited By ~ 15

Author(s):

Dana Alms ◽

Maren Fedrowitz ◽

Kerstin Römermann ◽

Andreas Noack ◽

Wolfgang Löscher

Keyword(s):

Endothelial Cell ◽

Rat Brain ◽

Cell Lines ◽

Cytostatic Drugs ◽

Capillary Endothelial Cell ◽

Brain Capillary Endothelial Cell ◽

Brain Capillary ◽

P Glycoprotein

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Donepezil, tacrine and α-phenyl-n-tert-butyl nitrone (PBN) inhibit choline transport by conditionally immortalized rat brain capillary endothelial cell lines (TR-BBB)

Archives of Pharmacal Research ◽

10.1007/bf02977674 ◽

2005 ◽

Vol 28 (4) ◽

pp. 443-450 ◽

Cited By ~ 21

Author(s):

Young-Sook Kang ◽

Kyeong-Eun Lee ◽

Na-Young Lee ◽

Tetsuya Terasaki

Keyword(s):

Endothelial Cell ◽

Rat Brain ◽

Cell Lines ◽

Capillary Endothelial Cell ◽

Brain Capillary Endothelial Cell ◽

Choline Transport ◽

Brain Capillary ◽

Tert Butyl

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mRNA Expression and Transport Characterization of Conditionally Immortalized Rat Brain Capillary Endothelial Cell Lines; a Newin vitroBBB Model for Drug Targeting

Journal of Drug Targeting ◽

10.3109/10611860008997912 ◽

2000 ◽

Vol 8 (6) ◽

pp. 357-370 ◽

Cited By ~ 75

Author(s):

Ken-Ichi Hosoya ◽

Tadayuki Takashima ◽

Kazuhiro Tetsuka ◽

Tatsuya Nagura ◽

Sumio Ohtsuki ◽

...

Keyword(s):

Endothelial Cell ◽

Mrna Expression ◽

Rat Brain ◽

Cell Lines ◽

Drug Targeting ◽

Capillary Endothelial Cell ◽

Brain Capillary Endothelial Cell ◽

Brain Capillary

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Interactions of racemic mefloquine and its enantiomers with P-glycoprotein in an immortalised rat brain capillary endothelial cell line, GPNT

Biochimica et Biophysica Acta (BBA) - General Subjects ◽

10.1016/s0304-4165(00)00160-4 ◽

2000 ◽

Vol 1524 (2-3) ◽

pp. 212-219 ◽

Cited By ~ 52

Author(s):

Yen-Thu Pham ◽

Anthony Régina ◽

Robert Farinotti ◽

Pierre-Olivier Couraud ◽

Irving W Wainer ◽

...

Keyword(s):

Endothelial Cell ◽

Rat Brain ◽

Cell Line ◽

Capillary Endothelial Cell ◽

Brain Capillary Endothelial Cell ◽

Brain Capillary ◽

Endothelial Cell Line ◽

P Glycoprotein

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Culture of mouse brain capillary endothelial cell lines that express factor VIII, γ-glutamyl transpeptidase, and form junctional complexes in vitro

In Vitro Cellular & Developmental Biology ◽

10.1007/bf02623679 ◽

1987 ◽

Vol 23 (11) ◽

pp. 775-781 ◽

Cited By ~ 18

Author(s):

Boro Dropulić ◽

Colin L. Masters

Keyword(s):

Endothelial Cell ◽

Factor Viii ◽

Cell Lines ◽

Mouse Brain ◽

Capillary Endothelial Cell ◽

Brain Capillary Endothelial Cell ◽

Brain Capillary ◽

Junctional Complexes ◽

Glutamyl Transpeptidase

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Glycerophospholipids and Acyl Group Changes in Rat Brain Capillary Endothelial Cell Fraction and the Liver during Development

Developmental Neuroscience ◽

10.1159/000112757 ◽

1981 ◽

Vol 4 (3) ◽

pp. 201-210 ◽

Cited By ~ 2

Author(s):

D.F. Matheson ◽

R. Oei ◽

Betty I. Roots

Keyword(s):

Endothelial Cell ◽

Rat Brain ◽

Cell Fraction ◽

Capillary Endothelial Cell ◽

Brain Capillary Endothelial Cell ◽

Brain Capillary

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Influence of tumor necrosis factor-α on the expression and function of P-glycoprotein in an immortalised rat brain capillary endothelial cell line, GPNT

Biochemical Pharmacology ◽

10.1016/s0006-2952(03)00340-x ◽

2003 ◽

Vol 66 (4) ◽

pp. 579-587 ◽

Cited By ~ 41

Author(s):

David Théron ◽

Sylvie Barraud de Lagerie ◽

Sylviane Tardivel ◽

Hélène Pélerin ◽

Philippe Demeuse ◽

...

Keyword(s):

Endothelial Cell ◽

Tumor Necrosis ◽

Tumor Necrosis Factor Α ◽

Capillary Endothelial Cell ◽

Brain Capillary Endothelial Cell ◽

Brain Capillary ◽

P Glycoprotein ◽

Factor Α ◽

And Function ◽

Necrosis Factor

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Transport of cyclosporin A across the brain capillary endothelial cell monolayer by P-glycoprotein

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ◽

10.1016/0167-4889(94)90047-7 ◽

1994 ◽

Vol 1222 (3) ◽

pp. 400-404 ◽

Cited By ~ 56

Author(s):

Akio Shirai ◽

Mikihiko Naito ◽

Tohru Tatsuta ◽

Jian Dong ◽

Kenji Hanaoka ◽

...

Keyword(s):

Endothelial Cell ◽

Cyclosporin A ◽

Cell Monolayer ◽

Endothelial Cell Monolayer ◽

Capillary Endothelial Cell ◽

Brain Capillary Endothelial Cell ◽

Brain Capillary ◽

P Glycoprotein ◽

The Brain

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Puromycin-based purification of rat brain capillary endothelial cell cultures. Effect on the expression of blood-brain barrier-specific properties

Journal of Neurochemistry ◽

10.1111/j.1471-4159.2004.03020.x ◽

2005 ◽

Vol 93 (2) ◽

pp. 279-289 ◽

Cited By ~ 209

Author(s):

N. Perrière ◽

PH. Demeuse ◽

E. Garcia ◽

A. Regina ◽

M. Debray ◽

...

Keyword(s):

Endothelial Cell ◽

Rat Brain ◽

Blood Brain Barrier ◽

Cell Cultures ◽

Brain Barrier ◽

Capillary Endothelial Cell ◽

Brain Capillary Endothelial Cell ◽

Brain Capillary ◽

Blood Brain ◽

Endothelial Cell Cultures

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Bilirubin Efflux By Brain Capillary Endothelial Cell Monolayers in Vitro: Role of P-Glycoprotein.

Pediatric Research ◽

10.1203/00006450-200410000-00063 ◽

2004 ◽

Vol 56 (4) ◽

pp. 673-673

Author(s):

Deryk Sequeira ◽

Monica J Daood ◽

Jon F Watchko ◽

Burhan Mahmood

Keyword(s):

Endothelial Cell ◽

Capillary Endothelial Cell ◽

Brain Capillary Endothelial Cell ◽

Brain Capillary ◽

Cell Monolayers ◽

P Glycoprotein

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Characteristics of L-citrulline transport through blood-brain barrier in the brain capillary endothelial cell line (TR-BBB cells)

Journal of Biomedical Science ◽

10.1186/s12929-017-0336-x ◽

2017 ◽

Vol 24 (1) ◽

Cited By ~ 7

Author(s):

Kyeong-Eun Lee ◽

Young-Sook Kang

Keyword(s):

Endothelial Cell ◽

Cell Line ◽

Blood Brain Barrier ◽

Brain Barrier ◽

Capillary Endothelial Cell ◽

Brain Capillary Endothelial Cell ◽

Brain Capillary ◽

Endothelial Cell Line ◽

Blood Brain ◽

The Brain

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