Modified Thrombolysis in Myocardial Infarction (TIMI) risk score to risk stratify patients in the emergency department with possible acute coronary syndrome

2007 ◽  
Vol 24 (2) ◽  
pp. 137-144 ◽  
Author(s):  
Zehra Jaffery ◽  
Michael P. Hudson ◽  
Gordon Jacobsen ◽  
Richard Nowak ◽  
James McCord
Keyword(s):  
Myocardial Infarction ◽  
Emergency Department ◽  
Acute Coronary Syndrome ◽  
Risk Score ◽  
Coronary Syndrome ◽  
Timi Risk Score

Predictive Value of Endocan Based on TIMI Risk Score on Major Adverse Cardiovascular Events After Acute Coronary Syndrome

Angiology ◽  
2018 ◽  
Vol 70 (10) ◽  
pp. 952-959 ◽  
Author(s):  
Mojtaba Ziaee ◽  
Sina Mashayekhi ◽  
Samad Ghaffari ◽  
Javad Mahmoudi ◽  
Parvin Sarbakhsh ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Coronary Syndrome ◽  
Risk Score ◽  
Troponin I ◽  
Multivariate Logistic Regression Analysis ◽  
Major Adverse Cardiovascular Events ◽  
Hospital Death ◽  
Coronary Syndrome ◽  
Creatine Kinase Mb ◽  
Timi Risk Score

We assessed the prognostic value of serum levels of endocan in patients with the acute coronary syndrome (ACS) through its correlation with the Thrombolysis in Myocardial Infarction (TIMI) risk score and compared the possible association with clinical outcomes. In this prospective cross-sectional study, we enrolled 320 patients with documented ST-segment elevation myocardial infarction (STEMI), non-STEMI (NSTEMI), or unstable angina (UA) who underwent diagnostic coronary angiography. Endocan was measured soon after admission in the emergency department. In-hospital death, heart failure, and recurrent infarction were considered major adverse cardiac events (MACEs). There was a significant positive correlation between endocan level and TIMI risk score and MACE. The optimal cutoff values of endocan to predict clinical end points were 3.45 ng/mL in patients with STEMI and 2.85 ng/mL in patients with UA/NSTEMI. Multivariate logistic regression analysis indicated that endocan independently correlated with MACE. Moreover, cardiac troponin I, creatine kinase-MB, and circulating endocan were found to be independently associated with MACE in patients with ACS. In conclusion, a high endocan level on hospital admission is an independent predictor of worse cardiovascular outcomes and higher TIMI risk score in patients with ACS.

Relation Between Thrombolysis in Myocardial Infarction Risk Score and One-Year Outcomes for Patients Presenting at the Emergency Department With Potential Acute Coronary Syndrome

2010 ◽  
Vol 105 (4) ◽  
pp. 441-444 ◽  
Author(s):  
Benjamin M. Weisenthal ◽  
Anna Marie Chang ◽  
Kristy M. Walsh ◽  
Mark J. Collin ◽  
Frances S. Shofer ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Emergency Department ◽  
Acute Coronary Syndrome ◽  
Risk Score ◽  
Coronary Syndrome ◽  
One Year

scholarly journals Application of the TIMI Risk Score for Unstable Angina and Non-ST Elevation Acute Coronary Syndrome to an Unselected Emergency Department Chest Pain Population

2006 ◽  
Vol 13 (1) ◽  
pp. 13-18 ◽  
Author(s):  
Charles V. Pollack ◽  
Frank D. Sites ◽  
Frances S. Shofer ◽  
Keara L. Sease ◽  
Judd E. Hollander
Keyword(s):  
Emergency Department ◽  
Acute Coronary Syndrome ◽  
Chest Pain ◽  
Unstable Angina ◽  
Risk Score ◽  
Coronary Syndrome ◽  
St Elevation ◽  
Elevation Acute Coronary Syndrome ◽  
Timi Risk Score

Modified TIMI risk score cannot be used to identify low-risk chest pain in the emergency department: a multicentre validation study

2013 ◽  
Vol 31 (4) ◽  
pp. 281-285 ◽  
Author(s):  
Stephen P J Macdonald ◽  
Yusuf Nagree ◽  
Daniel M Fatovich ◽  
Simon G A Brown
Keyword(s):  
Myocardial Infarction ◽  
Emergency Department ◽  
Chest Pain ◽  
Risk Stratification ◽  
Sensitivity And Specificity ◽  
Risk Score ◽  
Composite Outcome ◽  
Coronary Syndrome ◽  
Timi Score ◽  
Timi Risk Score

AimThe Thrombolysis in Myocardial Infarction (TIMI) risk score (range 0–7), used for emergency department (ED) risk stratification of patients with suspected acute coronary syndrome (ACS), underestimates risk associated with ECG changes or cardiac troponin elevation. A modified TIMI score (mTIMI, range 0–10), which gives increased weighting to these variables, has been proposed. We aimed to evaluate the performance of the mTIMI score in ED patients with suspected ACS.MethodsA multicentre prospective observational study enrolled patients undergoing assessment for possible ACS. TIMI and mTIMI scores were calculated. The study outcome was a composite of all-cause death, myocardial infarction or coronary revascularisation within 30 days.ResultsOf the 1666 patients, 219 (13%) reached the study outcome. Area under the receiver operating characteristic curve for the composite outcome was 0.80 (0.76 to 0.83) for the mTIMI score compared with 0.71 (0.67 to 0.74) for the standard TIMI score, p<0.001, but there was no significant difference for death or revascularisation outcomes. Sensitivity and specificity for the composite outcome were 0.96 (0.92 to 0.98) and 0.23 (0.20 to 0.26), respectively, at score 0 for TIMI and mTIMI. At score <2, sensitivity and specificity were 0.82 (0.77 to 0.87) and 0.53 (0.51 to 0.56) for mTIMI, and 0.74 (0.68 to 0.79) and 0.54 (0.51 to 0.56) for standard TIMI, respectively.ConclusionsmTIMI score performs better than standard TIMI score for ED risk stratification of chest pain, but neither is sufficiently sensitive at scores >0 to allow safe and early discharge without further investigation or follow-up. Observed differences in performance may be due to incorporation bias.

scholarly journals Prospective Validation of a Modified Thrombolysis In Myocardial Infarction Risk Score in Emergency Department Patients With Chest Pain and Possible Acute Coronary Syndrome

2010 ◽  
Vol 17 (4) ◽  
pp. 368-375 ◽  
Author(s):  
Erik P. Hess ◽  
Jeffrey J. Perry ◽  
Lisa A. Calder ◽  
Venkatesh Thiruganasambandamoorthy ◽  
Richard Body ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Emergency Department ◽  
Acute Coronary Syndrome ◽  
Chest Pain ◽  
Risk Score ◽  
Coronary Syndrome ◽  
Emergency Department Patients

Prognostic significance of multiple-detector computed tomography in conjunction with TIMI risk score for patients with non-ST elevation acute coronary syndrome

2008 ◽  
Vol 23 (3) ◽  
pp. 161-166 ◽  
Author(s):  
Mayumi Noda ◽  
Atsushi Takagi ◽  
Ryohei Kuwatsuru ◽  
Norio Mitsuhashi ◽  
Hiroshi Kasanuki
Keyword(s):  
Computed Tomography ◽  
Acute Coronary Syndrome ◽  
Risk Score ◽  
Prognostic Significance ◽  
Coronary Syndrome ◽  
St Elevation ◽  
Elevation Acute Coronary Syndrome ◽  
Timi Risk Score

scholarly journals Association of Thrombolysis in Myocardial Infarction (TIMI) Risk Score with Angiographic Severity of Coronary Artery Disease In Patients with Non-ST Elevation Acute Coronary Syndrome

2019 ◽  
Vol 15 (2) ◽  
pp. 68-73
Author(s):  
ABK Bashiruddin ◽  
Mohammad Ibrahim Chowdhury ◽  
Biplob Bhattacharjee ◽  
Abul Hossen Shahin ◽  
Syed Ali Ahsan ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
High Risk ◽  
Risk Score ◽  
Gensini Score ◽  
Coronary Syndrome ◽  
Timi Score ◽  
Artery Disease ◽  
Timi Risk Score

Background: Clinical guidelines recommend that optimal management of acute coronary syndrome (ACS) should include patient risk stratification. Predicting the anatomical extension of coronary artery disease (CAD) is also potentially useful for clinical decision. Objective: The objective of our study was to determine whether the TIMI risk score correlates with the angiographic extent and severity of CAD in patients with NSTE- ACS. Materials and Methods: This was a cross-sectional observational study carried out in the Department of Cardiology, Chattogram Medical College Hospital (CMCH) from September 2017 to May 2018. A total of 200 patients diagnosed with NSTE- Acute Coronary Syndrome were included as sample by purposive sampling method. TIMI risk score for each patient was calculated and the patients were stratified into 3 groups according to the TIMI risk score: low risk (0-2); intermediate risk (3-4); high risk (5-7). The severity of the CAD was assessed by Vessel score and Gensini score. Result: The mean ± SD of the age of study population was 53.7 ±10.8 years (range 37–77) and 142 (71%) were male. Regarding cardiovascular risk factors, 137 (68.5%) patients had diabetes mellitus, 83 (41.5%) had dyslipidaemia, 155 (77.5%) had hypertension, 136 (68%) were current smoker and 70 (35%) had a family history of CAD. The Gensini score was higher in patients at high risk TIMI group (p<0.001). Moreover, there was a signiûcant positive correlation between the TIMI and Gensini score (r=0.446,p<0.001). TIMI score can predict significant CAD moderately well (area under the curve 0.661, p=0.001). Patients with TIMI score > 4 were more likely to have significant three vessel CAD (65.9%) versus those with TIMI risk score 3-4 (17.9%) and TIMI risk score < 3 (2%) (p< 0.001). Conclusion: Study showed the TIMI score is significantly correlated with the extent of CAD as assessed by the Gensini score. It is accurate for predicting severe CAD among NSTE-ACS patients. University Heart Journal Vol. 15, No. 2, Jul 2019; 68-73

Predictive value of the Canada Acute Coronary Syndrome risk score for post-acute myocardial infarction infection

2020 ◽  
Vol 71 ◽  
pp. 57-61 ◽  
Author(s):  
YuanHui Liu ◽  
YiNing Dai ◽  
JiaYing Chen ◽  
Cheng Huang ◽  
ChongYang Duan ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Acute Coronary Syndrome ◽  
Risk Score ◽  
Predictive Value ◽  
Coronary Syndrome

Novel Emergency Department Risk Score Discriminates Acute Coronary Syndrome Among Chest Pain Patients With Known Coronary Artery Disease

2016 ◽  
Vol 15 (4) ◽  
pp. 138-144 ◽  
Author(s):  
Matthew T. Crim ◽  
Scott A. Berkowitz ◽  
Mustapha Saheed ◽  
Jason Miller ◽  
Amy Deutschendorf ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Emergency Department ◽  
Acute Coronary Syndrome ◽  
Chest Pain ◽  
Coronary Artery ◽  
Risk Score ◽  
Coronary Syndrome ◽  
Artery Disease ◽  
Pain Patients
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