scholarly journals Elevated lipoprotein(a) as a new risk factor of cerebral venous sinus thrombosis: association with fibrin clot properties

2018 ◽  
Vol 47 (1) ◽  
pp. 8-15 ◽  
Author(s):  
Anna Aleksandra Skuza ◽  
Maciej Polak ◽  
Anetta Undas
Keyword(s):  
Risk Factor ◽  
Sinus Thrombosis ◽  
Fibrin Clot ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Venous Sinus Thrombosis ◽  
Lipoprotein A

scholarly journals Cerebral Venous Sinus Thrombosis: Incidence and Hyperhomocysteinemia as a Risk Factor in Japanese Patients

2017 ◽  
Vol 08 (05) ◽  
Author(s):  
Makoto Takemaru ◽  
Masaru Kuriyama ◽  
Takahiro Himeno ◽  
Yuji Shiga ◽  
Yuhei Kanaya ◽  
...  
Keyword(s):  
Risk Factor ◽  
Sinus Thrombosis ◽  
Japanese Patients ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Venous Sinus Thrombosis

scholarly journals Altered Fibrin Clot Properties in Patients With Cerebral Venous Sinus Thrombosis

Stroke ◽  
2015 ◽  
Vol 46 (9) ◽  
pp. 2665-2668 ◽  
Author(s):  
Jakub Siudut ◽  
Maciej Świat ◽  
Anetta Undas
Keyword(s):  
Sinus Thrombosis ◽  
Fibrin Clot ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Venous Sinus Thrombosis

scholarly journals Thyroid Diseases Are an Underestimated Risk Factor for Cerebral Venous Sinus Thrombosis

2020 ◽  
Vol 11 ◽  
Author(s):  
Maren Hieber ◽  
Charlotte von Kageneck ◽  
Cornelius Weiller ◽  
Johann Lambeck
Keyword(s):  
Risk Factor ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Thyroid Diseases ◽  
Venous Sinus ◽  
Venous Sinus Thrombosis

scholarly journals Cerebral Venous Sinus Thrombosis (CVST) in a Middle-Aged Female with Clustering of Risk Factors

2021 ◽  
Vol 10 (34) ◽  
pp. 2960-2963
Author(s):  
Maria Prothasis ◽  
Yash Gupte ◽  
Sourya Acharya ◽  
Samarth Shukla ◽  
Neema Acharya
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Venous Thromboembolism ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Factor V ◽  
Venous Sinus Thrombosis

Thrombosis of cerebral venous channel is a known complication of hypercoagulable states. Hyperhomocysteinaemia is a known hypercoagulable state. Obesity is a modern-day global epidemic. Disorders such as myocardial infarction (MI), stroke, and venous thromboembolism are on the rising trend and its increased morbidity and mortality is being associated with obesity. To date, however, the knowledge about the association between obesity and adult cerebral venous thrombosis (CVT) is sparse. We report a 44-year-old young morbidly obese metabolically unhealthy female who presented with headache, nausea, vomiting and giddiness. On evaluation, magnetic resonance venogram showed cerebral venous sinus thrombosis. On investigations, she had concomitant hyperhomocysteinaemia and metabolic syndrome. Cerebral venous sinus thrombosis causing stroke in young adults is uncommon with various conditions precipitating it.1,2,3 Severe headache (70 - 90 %), focal lateralized signs (25 % - 75 %), seizures (30 – 40 %) as well as behavioural symptoms such as delirium, amnesia, and disturbances in consciousness are the various associated clinical symptoms. The known inherited hypercoagulable risk factors that cause CVST are gain of function mutations in the genes encoding factor V (factor V Leiden) and prothrombin, Protein C, S and antithrombin III deficiency. Hyperhomocysteinaemia, is a known risk factor for causing venous thrombosis of the lower limbs. However, till date there is no data available showing its role in causing cerebral venous thrombosis. The interaction between genetic and acquired determinants result in high plasma levels of total homocysteine (tHcy).4,5,6 Vitamins such as folic acid, pyridoxine, and cobalamin are involved in the metabolic pathways of homocysteine and its deficiencies represent the acquired determinants. Venous thromboembolism (VTE) comprises of deep vein thrombosis of the leg and pulmonary embolism and obesity is now being recognised as one of the risk factors causing it. The risk of VTE is approximately increased to 2-fold in an individual with a body mass index (BMI) (calculated as weight in kilograms divided by height in meters squared) of 30 or more compared with a normal BMI (< 25), and higher BMIs increase more risk with approximately 3 times higher risk in individuals with a BMI greater than 40.7, 8,9 Again obesity as a risk factor for CVST is less known.

scholarly journals CORRELATION BETWEEN CEREBRAL VENOUS SINUS THROMBOSIS AND SERUM HOMOCYSTEINE LEVELS IN A TERTIARY CARE HOSPITAL, INDIA A PROSPECTIVE OBSERVATIONAL STUDY

2021 ◽  
Vol 9 (01) ◽  
pp. 251-274
Author(s):  
Sanskriti Kamran ◽  
◽  
Sanjay Sharma ◽  
Sayani Banerjee ◽  
Sujoy Das Thakur ◽  
...  
Keyword(s):  
Risk Factor ◽  
Sinus Thrombosis ◽  
Tertiary Care ◽  
Clinical History ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Care Hospital ◽  
Fasting Serum ◽  
Venous Sinus Thrombosis ◽  
Serum Homocysteine

Objective: To study correlation between Cerebral Venous Sinus Thrombosis and Serum Homocysteine levels. Patients and Methods: 76 patients having Cerebral Venous Thrombosis were admitted to our hospital from September 2017 to September 2019. In each patient fasting serum homocysteine levels and serum B12 levels were taken and analyzed. Every patient was subjected to a detailed clinical history and neurological examination. In each patient fasting serum homocysteine levels and serum B12 levels were done. The serum homocysteine levels were done by kinetic biochemistry using R1 and R 2 reagents. The serum B12 levels were done by using ELISA Technique. On the basis of serum homocysteine levels, the patients were divided into 4 categories: Normal Level, Mild Hyperhomocysteinrmia, Moderate Hyperhomocysteinemia and Severe Hyperhomocysteinemia. On the basis of serum B12 levels, the patients were again divided into 4 categories: Severe Deficiency, Mild Deficiency, Normal range and High levels. Conclusion: Hyperhomocysteinemia could be a risk factor accounting forCerebral Venous Sinus Thrombosis. The results of this study have shown that homocysteine levels were significantly higher in CVST patients and serum hyperhomocysteinemia is one of the risk factor in the etiology of Cerebral Venous Sinus Thrombosis patients. Though, Serum B12 levels showed no correlation in patients of CVST. Thus, Serum homocysteine estimation needs to be sent from emergency department of all patients with diagnosis of Cerebral Venous Sinus Thrombosis.

Long-term prognosis of cerebral venous sinus thrombosis in childhood

2004 ◽  
Vol 46 (08) ◽  
Author(s):  
Els LLM De Schryver ◽  
Ingrid Blom ◽  
Kees PJ Braun ◽  
L Jaap Kappelle ◽  
Gabriël JE Rinkel ◽  
...  
Keyword(s):  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Venous Sinus Thrombosis ◽  
Long Term Prognosis
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