scholarly journals Genetic association between SNPs in the DGAT1 gene and milk production traits in Murrah buffaloes

2016 ◽  
Vol 48 (7) ◽  
pp. 1421-1426 ◽  
Author(s):  
Ana Cláudia de Freitas ◽  
Gregório Miguel Ferreira de Camargo ◽  
Nedenia Bonvino Stafuzza ◽  
Rusbel Raul Aspilcueta-Borquis ◽  
Guilherme Costa Venturini ◽  
...  
Keyword(s):  
Genetic Association ◽  
Milk Production ◽  
Production Traits ◽  
Milk Production Traits ◽  
Murrah Buffaloes ◽  
Dgat1 Gene

Single nucleotide polymorphism in STAT5A could not endorse variation in milk production traits in Indian bovine population

2021 ◽  
Author(s):  
Sudhakar Krovvidi ◽  
Thiruvenkadan K. Aranganoor ◽  
Saravanan Ramasamy ◽  
Murali Nagarajan
Keyword(s):  
Milk Production ◽  
Milk Fat ◽  
Bovine Milk ◽  
Fat Content ◽  
Production Traits ◽  
Crossbred Cattle ◽  
Milk Production Traits ◽  
Milk Traits ◽  
Murrah Buffaloes ◽  
Genetic Groups

Abstract The Signal Transducer and Activator of Transcription 5A (STAT5A) gene involved in activating the transcription of milk protein genes was predicted to be influencing milk production traits. The present study was undertaken to investigate the suitability of the polymorphism of STAT5A as a marker for milk traits in Ongole, crossbred cattle and Murrah buffaloes from Southern India. Blood samples (n = 502) for DNA isolation and milk samples (n = 222) from different genetic groups were collected from various farms. The gene variants upon polymerase chain reaction–restriction fragment length polymorphism (PCR-RFLP) on the exon 7 region of STAT5A were subjected to GLM analysis to evaluate their association with milk production traits. The frequencies of C and T alleles at the STAT5A/AvaI locus were 0.98 and 0.02 (Jersey crossbred), 0.94 and 0.06 [Holstein-Friesian (HF) crossbred], 0.97 and 0.03 (Ongole). T allele was not observed in Murrah buffaloes. The least squares mean lactation milk yield of CC and CT genotypes of STAT5A were 2,096.90 ± 48.63 and 2,294.41 ± 215.85 kg in Jersey crossbred, 2,312.92 ± 91.01 and 2,392.82 ± 207.66 kg in HF crossbred and 528.40 ± 22.10 and 396.37 ± 76.17 kg in Ongole cattle, respectively. The milk fat content of the CC genotype was higher (P > 0.05) in Jersey crossbred cattle. The CT genotypes of Ongole and HF crossbred cattle recorded a higher fat per cent than the CC genotypes. Significant associations were not observed in support of STAT5A as a marker for milk production traits in either Ongole or crossbred cattle of indicine admixture and no reason could be found to consider this locus as universal markers for milk production traits in indicine cattle and buffaloes. Considering the monomorphic nature of the gene in buffaloes and their higher milk fat content as compared to bovine milk, much remains to be explored regarding the underlying differences across the bovine and the bubaline species.

scholarly journals Polymorphism identification in goat DGAT1 and STAT5A genes and association with milk production traits

2013 ◽  
Vol 58 (No. 7) ◽  
pp. 321-327 ◽  
Author(s):  
X.P. An ◽  
J.X. Hou ◽  
H.B. Zhao ◽  
L. Bai ◽  
J.Y. Peng ◽  
...  
Keyword(s):  
Dna Sequencing ◽  
Milk Production ◽  
Milk Yield ◽  
Milk Fat ◽  
Production Traits ◽  
Milk Production Traits ◽  
Dgat1 Gene ◽  
Pcr Rflp ◽  
Stat5a Gene ◽  
T Locus

Polymorphisms of DGAT1 and STAT5A genes in Xinong Saanen and Guanzhong goat breeds were investigated. PCR-RFLP, SSCP, and DNA sequencing were used to identify three SNPs: DQ380250:g.407_408insC in the DGAT1 gene, AJ237937:g.6798C&gt;T and g.6852C&gt;T in the STAT5A gene. In DGAT1 g.407_408insC locus, the frequencies of C<sup>&ndash;</sup> allele were 0.79&ndash;0.85, and frequencies of C<sup>+</sup> allele were 0.21&ndash;0.15. At STAT5A g.6852C&gt;T locus, frequencies of C allele were 0.70&ndash;0.72, and frequencies of T allele were 0.30&ndash;0.28. Compared with goats with DGAT1 C<sup>&ndash;</sup>C<sup>&ndash;</sup>, those with C<sup>&ndash;</sup>C<sup>+</sup> genotype had greater milk fat (P &lt; 0.05). The goats with STAT5A CT had greater milk yield than those with CC genotype (P &lt; 0.05). The results showed that does with C<sup>&ndash;</sup>C<sup>&ndash;</sup>CT and C<sup>&ndash;</sup>C<sup>+</sup>CT yielded more milk than those with C<sup>&ndash;</sup>C<sup>&ndash;</sup>CC(P &lt; 0.05). In addition, does with C<sup>&ndash;</sup>C<sup>+</sup>CT had the highest milk fat in comparison with other combination genotypes (P &lt; 0.05). &nbsp;

scholarly journals Evaluation of DGAT1-exon 8 K232A substitution in Gir and Kankrej (Bos indicus), Indian origin cattle and its association with milk production traits

Genetika ◽  
2017 ◽  
Vol 49 (2) ◽  
pp. 627-634
Author(s):  
Jainikkumar Patel ◽  
Jenabhai Chauhan
Keyword(s):  
Allele Frequency ◽  
Milk Production ◽  
Bos Indicus ◽  
Cattle Breed ◽  
Production Traits ◽  
Milk Production Traits ◽  
Fat Percentage ◽  
Indian Origin ◽  
Dgat1 Gene ◽  
Total Milk

The aim of the present study was to screen the genotype profile of bovine DGAT1 gene among Gir and Kankrej cattle in Gujarat, India. Total number of 200 Gir cattle and 100 Kankrej cattle were evaluated for CfrI-RFLP based genotyping of DGAT1 gene. We observed that only two genotypes (KK and KA) exist among the studied population with the alleles frequency of 0.925 (n=170) and 0.075 (n=30), respectively for K and A in Gir cattle as well as 0.895 (n=79) and 0.105 (n=21) respectively in Kankrej cattle. The overall calculated allele frequency for K and A was 0.915 and 0.085, respectively in both zebu (Bos indicus) cattle. Association of genotypes with milk production traits revealed that KA had significant (P<0.05) effect on total milk yield, as compared to KK in Gir and Kankrej cattle breed. Similarly, KK genotype had significant (P<0.05) effect on fat percentage, as compared to KA in Gir and Kankrej.

Effect of Breed and Some Non - Genetic Factors on Milk Production and Some Proportions of Its Chemical Components in Two Breeds of Local Sheep

2020 ◽  
Vol 10 (1) ◽  
pp. 227-231
Author(s):  
Rahman Hussein AL-Qasimi ◽  
Shatha Mohammed Abbas ◽  
Allawi L.D. AL-Khauzai
Keyword(s):  
Milk Production ◽  
Genetic Factors ◽  
Chemical Components ◽  
Lactation Period ◽  
Production Traits ◽  
Milk Production Traits ◽  
Fat Percentage ◽  
Awassi Sheep ◽  
Total Milk ◽  
Milk Components

The study was carried out on 19 ewes of local Awassi sheep and 12ewes local Arabi sheep in the Al-kafeel sheep station Karbala, to determine the effect of breed and some non-genetic factors such as (sex of the lamb, type of birth, age and weight of ewes at birth) on daily and total milk production and lactation period and some of milk components (fat, protein and lactose). The results showed that a significant effect (P <0.05) of the breed on milk production traits where Awassi sheep recorded the highest mean (0.91 kg , 101.63 kg , 104.86 day) compared to the Arabi sheep she was means (0.77 kg , 88.15 kg , 99.15 day) respectively. As well as in proportions of milk components with mean( 5.1 , 4.90 , 5.51) % respectively compared to the Arabi sheep (4.70 . 4.20 . 4.89) ewes with male lambs also exceeded superior ewes with female lambs in daily and total milk production and the lactation period the sex of the lamb did not affect the proportions of milk components the weight of the ewes had a significant effect (P <0.05) in milk production attributes with superior weight of ewes on lower ewes and did not affect the proportions of milk ingredients except for lactose. The type of birth and the age of the ewes did not have a significant effect in all the studied traits except for the superiority (P<0.05) of young ewes on age ewes in the fat percentage of milk.

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