Abstract
IntroductionHealth system planning requires careful assessment of accidental carbon monoxide poisoning (ACOP) epidemiology, but data of this disease are scarce or non-existent in many countries. This article investigates the global burden of ACOP based on the Global Burden of Disease Study 2019 (GBD 2019) and the World Bank database.Materials and MethodsNumbers and age-standardized rates (ASR) of ACOP incidence, prevalence, deaths, Disability-Adjusted Life Years (DALYs), Years Lived with Disability (YLDs), and Years of Life Lost (YLLs) were analysed at global, regional, and national level. The estimated annual percentage change (EAPC) of age-standardized rates (ASR) was calculated by generalizing the linear model with a Gaussian distribution. Age, sex, and economics parameters are included to access their internal relevance.ResultsGlobally, in 2019, there were approximately 0.97 million ACOP incidence cases (95% CI 0.66 million to 1.4 million), and 41,142 (95%UI 32957 to 45934) people died from it. Compared with 1990, the morbidity and mortality of ACOP in 2019 are on a downward trend. By sexes, from 1990 to 2019, females have a higher morbidity and lower mortality. This article also finds that the relevant parameters of ACOP are closely related to the economic parameters. This correlation enables us to evaluate the level and status of public health services in various countries.DiscussionACOP is the most common toxic disease in the world. In 2019, the number of patients who die from ACOP exceeded that of patients poisoned by all other means. In global health decision-making, especially in regions with high-middle and high SDI, more attention should be paid.ConclusionAs the population ageing in areas with High-middle SDI and High SDI increases, the potential burden of ACOP is increasing, presenting the governments with an increasing demand for acute care, rehabilitation, and support services. The results of this study can be used by the health authorities to consider the burden of ACOP that could be addressed with preventive and therapeutic measures.
Global, Regional, and National Burden of Accidental Carbon Monoxide Poisoning, 1990–2019: A Systematic Analysis for the Global Burden of Disease Study 2019
